(Q38329721)

2 September 2017

title

The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding (English)

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2 September 2017

7

Zeger Debyser

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Yves Engelborghs

5

object named as

Yves Engelborghs

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2 September 2017

6

Frauke Christ

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2 September 2017

Katrien Busschots

1

1 reference

2 September 2017

Jo Vercammen

2

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2 September 2017

Stéphane Emiliani

3

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2 September 2017

Richard Benarous

4

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2 September 2017

language of work or name

English

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publication date

4 March 2005

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

280

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2 September 2017

issue

18

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2 September 2017

page(s)

17841-17847

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HIV integrase, a brief overview from chemistry to therapeutics

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Molecular mechanisms in retrovirus DNA integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

DNA-induced polymerization of HIV-1 integrase analyzed with fluorescence fluctuation spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

High-level expression of active HIV-1 integrase from a synthetic gene in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

HIV Integration: Ini1 for integration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411681200

The Human Polycomb Group EED Protein Interacts with the Integrase of Human Immunodeficiency Virus Type 1

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M411681200

A previously unidentified host protein protects retroviral DNA from autointegration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

LEDGF/p75: a novel nuclear autoantigen at the crossroads of cell survival and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Lens epithelium-derived growth factor: effects on growth and survival of lens epithelial cells, keratinocytes, and fibroblasts

21 January 2018

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Transcriptional regulation of the antioxidant protein 2 gene, a thiol-specific antioxidant, by lens epithelium-derived growth factor to protect cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Lens epithelium-derived growth factor (LEDGF/p75) and p52 are derived from a single gene by alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Molecular and Genetic Determinants of Rous Sarcoma Virus Integrase for Concerted DNA Integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Interactions of the human T-cell leukemia virus type-II integrase with the conserved CA in the retroviral long terminal repeat end.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Differential multimerization of Moloney murine leukemia virus integrase purified under nondenaturing conditions.

21 January 2018

1 reference

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Heuristic statistical analysis of fluorescence fluctuation data with bright spikes: application to ligand binding to the human serotonin receptor expressed in Escherichia coli cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Cellular Distribution and Karyophilic Properties of Matrix, Integrase, and Vpr Proteins from the Human and Simian Immunodeficiency Viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Characterization of the nuclear import pathway for HIV-1 integrase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Intracellular transport of human immunodeficiency virus type 1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Targeting survival: integration site selection by retroviruses and LTR-retrotransposons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Transcription start regions in the human genome are favored targets for MLV integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

Spatial and temporal dynamics of two alternatively spliced regulatory factors, lens epithelium-derived growth factor (ledgf/p75) and p52, in the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

HIV-1 integration in the human genome favors active genes and local hotspots

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411681200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411681200

1 reference

2 September 2017

1 reference