(Q38331755)

2 September 2017

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title

Cell death by autophagy: emerging molecular mechanisms and implications for cancer therapy (English)

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2 September 2017

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1

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2 September 2017

D Kögel

2

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2 September 2017

language of work or name

English

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publication date

26 January 2015

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2 September 2017

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2 September 2017

volume

34

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2 September 2017

issue

40

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2 September 2017

page(s)

5105-5113

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https://scigraph.springernature.com/pub.10.1038/onc.2014.458

2 September 2017

exact match

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cites work

The biochemistry of apoptosis

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Caspase-independent cell death

21 January 2018

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Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

21 January 2018

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Crosstalk between apoptosis, necrosis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Self-consumption: the interplay of autophagy and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Apoptosis meets autophagy-like cell death in the ischemic penumbra: Two sides of the same coin?

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Autophagy and signaling: their role in cell survival and cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Regulation mechanisms and signaling pathways of autophagy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

microRNA-101 is a potent inhibitor of autophagy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

The autophagy effector Beclin 1: a novel BH3-only protein

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Autophagy as a cell death and tumor suppressor mechanism

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Autosis: a new addition to the cell death Tower of Babel

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Autophagic programmed cell death by selective catalase degradation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

An inhibition of p62/SQSTM1 caused autophagic cell death of several human carcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3.

21 January 2018

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Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Autophagic cell death: Loch Ness monster or endangered species?

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Autophagy in Dictyostelium: genes and pathways, cell death and infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Autophagy is required for necrotic cell death in Caenorhabditis elegans.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

ApoL1, a BH3-only lipid-binding protein, induces autophagic cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Control of autophagic cell death by caspase-10 in multiple myeloma

21 January 2018

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Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway

21 January 2018

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Association and dissociation of autophagy, apoptosis and necrosis by systematic chemical study.

21 January 2018

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Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

21 January 2018

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Bcl-2 inhibition of autophagy: a new route to cancer?

21 January 2018

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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

21 January 2018

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BH3 mimetics reactivate autophagic cell death in anoxia-resistant malignant glioma cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Breaking Chemoresistance and Radioresistance with [213Bi]anti-CD45 Antibodies in Leukemia Cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

(-)-gossypol inhibits growth and promotes apoptosis of human head and neck squamous cell carcinoma in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

BNIP3 regulates AT101 [(-)-gossypol] induced death in malignant peripheral nerve sheath tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Gossypol and an HMT G9a inhibitor act in synergy to induce cell death in pancreatic cancer cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.458

Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

The novel BH-3 mimetic apogossypolone induces Beclin-1- and ROS-mediated autophagy in human hepatocellular carcinoma [corrected] cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

The Bcl-2 homology domain 3 mimetic gossypol induces both Beclin 1-dependent and Beclin 1-independent cytoprotective autophagy in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Inhibition of MCL-1 enhances lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Lapatinib induces autophagic cell death and inhibits growth of human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Poly(ADP-ribose) polymerase 1 modulates the lethality of CHK1 inhibitors in mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

The combination of a histone deacetylase inhibitor with the Bcl-2 homology domain-3 mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Distinct cellular and therapeutic effects of obatoclax in rituximab-sensitive and -resistant lymphomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

The BH3-mimetic GX15-070 induces autophagy, potentiates the cytotoxicity of carboplatin and 5-fluorouracil in esophageal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

GX15-070 (obatoclax) induces apoptosis and inhibits cathepsin D- and L-mediated autophagosomal lysis in antiestrogen-resistant breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Targeting mitochondrial apoptosis by betulinic acid in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Betulinic acid-induced mitochondria-dependent cell death is counterbalanced by an autophagic salvage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Survival and death strategies in glioma cells: autophagy, senescence and apoptosis triggered by a single type of temozolomide-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Ambra1 regulates autophagy and development of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Autophagy induced by suberoylanilide hydroxamic acid in Hela S3 cells involves inhibition of protein kinase B and up-regulation of Beclin 1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

The Bcl-2-Beclin 1 interaction in (-)-gossypol-induced autophagy versus apoptosis in prostate cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.458

Suberoylanilide hydroxamic acid (SAHA) induces apoptosis or autophagy-associated cell death in chondrosarcoma cell lines.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25619832

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2014.458

1 reference

Dimensions Publication ID

2 September 2017

1048518485

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1 reference