(Q36352540)

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Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22955917%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition (English)

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12 February 2020

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multiple myeloma

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1

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12 February 2020

7

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12 February 2020

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12 February 2020

Teresa Calimeri

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12 February 2020

Paul G. Richardson

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Paul Richardson

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12 February 2020

Kenneth C. Anderson

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Kenneth C Anderson

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12 February 2020

Nikhil V Munshi

17

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Nikhil Munshi

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12 February 2020

5

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Teru Hideshima

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12 February 2020

Mariateresa Fulciniti

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Mariateresa Fulciniti

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12 February 2020

Dharminder Chauhan

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12 February 2020

12

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Sun-Young Kong

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12 February 2020

Antonia Cagnetta

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Antonia Cagnetta

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12 February 2020

Jana Jakubikova

11

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Jana Jakubikova

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12 February 2020

Francesca Cottini

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Francesca Cottini

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12 February 2020

13

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Franco Patrone

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12 February 2020

Alessio Nencioni

14

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Alessio Nencioni

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12 February 2020

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Yu-Tzu Tai

4

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12 February 2020

Marco Gobbi

15

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12 February 2020

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5 September 2012

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12 February 2020

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Europe PubMed Central

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12 February 2020

120

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12 February 2020

17

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Europe PubMed Central

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12 February 2020

3519-3529

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Europe PubMed Central

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12 February 2020

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11 June 2022

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Compromising the unfolded protein response induces autophagy-mediated cell death in multiple myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482862

30 September 2017

Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells

1 reference

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30 September 2017

TFEB links autophagy to lysosomal biogenesis

1 reference

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30 September 2017

Principles and current strategies for targeting autophagy for cancer treatment

1 reference

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30 September 2017

Targeting autophagy augments in vitro and in vivo antimyeloma activity of DNA-damaging chemotherapy

1 reference

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30 September 2017

Autophagy and metabolism

1 reference

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1 reference

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30 September 2017

Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.

1 reference

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Methods in mammalian autophagy research

1 reference

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30 September 2017

mTOR regulation of autophagy

1 reference

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mTOR and cancer: many loops in one pathway.

1 reference

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Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.

1 reference

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Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

1 reference

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30 September 2017

NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway

1 reference

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30 September 2017

Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner

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Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

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Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt

1 reference

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Nicotinamide adenine dinucleotide based therapeutics

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NAD depletion by FK866 induces autophagy

1 reference

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Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets

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Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade.

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1 reference

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12 December 2020

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10.1182/BLOOD-2012-03-416776

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12 February 2020

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12 February 2020

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12 February 2020

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