(Q39642626)

13 September 2017

NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response (English)

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13 September 2017

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B Wang

1

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13 September 2017

M K Hasan

2

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13 September 2017

E Alvarado

3

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13 September 2017

H Yuan

4

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13 September 2017

H Wu

5

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13 September 2017

W Y Chen

6

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13 September 2017

language of work or name

English

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publication date

18 October 2010

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13 September 2017

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13 September 2017

30

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13 September 2017

907-921

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13 September 2017

8

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https://scigraph.springernature.com/pub.10.1038/onc.2010.468

13 September 2017

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cites work

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1038%2FONC.2010.468

Mitochondria, oxidants, and aging

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.468

Adult-onset calorie restriction and fasting delay spontaneous tumorigenesis in p53-deficient mice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.468

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

SirT1 regulates energy metabolism and response to caloric restriction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Proteolytic regulation of Forkhead transcription factor FOXO3a by caspase-3-like proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Control of multidrug resistance gene mdr1 and cancer resistance to chemotherapy by the longevity gene sirt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Sirtuin 1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Inflammation in prostate carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Hormonal control of androgen receptor function through SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

RETRACTED: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Nampt: linking NAD biology, metabolism and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Poly(adp-ribose) polymerase inhibitors: a novel drug class with a promising future

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

SIRT1 is significantly elevated in mouse and human prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

N-terminal acetylation of cellular proteins creates specific degradation signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

SIRT1 expression is associated with poor prognosis of diffuse large B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Expression and prognostic significance of SIRT1 in ovarian epithelial tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

FOXO3a: a novel player in thyroid carcinogenesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Negative control of p53 by Sir2alpha promotes cell survival under stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Mammalian SIRT1 represses forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Genomic organization of the gene coding for human pre-B-cell colony enhancing factor and expression in human fetal membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Akt activation promotes degradation of tuberin and FOXO3a via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Sirtuins: critical regulators at the crossroads between cancer and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Poly(ADP-ribose): novel functions for an old molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Imaging techniques for prostate cancer: implications for focal therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Target validation for genomics using peptide-specific phage antibodies: a study of five gene products overexpressed in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Autotoxicity, methylation and a road to the prevention of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

Extension of human cell lifespan by nicotinamide phosphoribosyltransferase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.468

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.468

1 reference

13 September 2017

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