(Q42798510)

7 November 2017

title

SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol (English)

1 reference

7 November 2017

G Boily

1

1 reference

7 November 2017

X H He

2

1 reference

7 November 2017

B Pearce

3

1 reference

7 November 2017

K Jardine

4

1 reference

7 November 2017

M W McBurney

5

1 reference

7 November 2017

language of work or name

English

0 references

publication date

8 June 2009

1 reference

7 November 2017

1 reference

7 November 2017

volume

28

1 reference

7 November 2017

issue

32

1 reference

7 November 2017

page(s)

2882-2893

1 reference

https://scigraph.springernature.com/pub.10.1038/onc.2009.147

7 November 2017

exact match

0 references

cites work

Phosphorylation of HuR by Chk2 regulates SIRT1 expression

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

SirT1 regulates energy metabolism and response to caloric restriction in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Mechanism of human SIRT1 activation by resveratrol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Resveratrol: from basic science to the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Roles of insulin-like growth factor (IGF) binding proteins in regulating IGF actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Hormonal control of androgen receptor function through SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Strong expression of a longevity-related protein, SIRT1, in Bowen's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

SIRT1 is significantly elevated in mouse and human prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

SIRT1 expression is associated with poor prognosis of diffuse large B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Substrate-specific activation of sirtuins by resveratrol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kappaB and AP-1 as prime targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Negative control of p53 by Sir2alpha promotes cell survival under stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

SIRT1 controls endothelial angiogenic functions during vascular growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Function of the SIRT1 protein deacetylase in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

The Sirt1 deacetylase modulates the insulin-like growth factor signaling pathway in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

Extension of human cell lifespan by nicotinamide phosphoribosyltransferase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.147

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.147

1 reference

Dimensions Publication ID

7 November 2017

1023025239

0 references

1 reference