(Q46709814)

24 December 2017

title

Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells (English)

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24 December 2017

author name string

Ota H

1

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24 December 2017

Tokunaga E

2

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24 December 2017

Chang K

3

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24 December 2017

Hikasa M

4

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24 December 2017

Iijima K

5

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24 December 2017

Eto M

6

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24 December 2017

Kozaki K

7

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24 December 2017

Akishita M

8

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24 December 2017

Ouchi Y

9

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24 December 2017

Kaneki M

10

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24 December 2017

language of work or name

English

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publication date

1 January 2006

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24 December 2017

published in

Oncogene

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24 December 2017

volume

25

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24 December 2017

page(s)

176-185

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24 December 2017

issue

2

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24 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209049

exact match

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SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

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Induction of apoptosis and inhibition of papilloma formation may signal a new role for okadaic acid

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Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction

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Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin

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Identification of a quinoxaline derivative that is a potent telomerase inhibitor leading to cellular senescence of human cancer cells

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Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.

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The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

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Ras-dependent growth factor regulation of MEK kinase in PC12 cells

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7 January 2021

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

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7 January 2021

Negative control of p53 by Sir2alpha promotes cell survival under stress

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Human fibroblasts require the Rb family of tumor suppressors, but not p53, for PML-induced senescence.

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Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock

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7 January 2021

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

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7 January 2021

A review of depsipeptide and other histone deacetylase inhibitors in clinical trials

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7 January 2021

Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report

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7 January 2021

Tumor senescence as a determinant of drug response in vivo

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7 January 2021

Histone deacetylase inhibitors in clinical development

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7 January 2021

Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells

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7 January 2021

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

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7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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7 January 2021

Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209049

7 January 2021

Telomeres, stem cells, senescence, and cancer

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7 January 2021

Hallmarks of senescence in carcinogenesis and cancer therapy

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7 January 2021

Inducible nitric-oxide synthase and NO donor induce insulin receptor substrate-1 degradation in skeletal muscle cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209049

7 January 2021

BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone.

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7 January 2021

Metabolic stabilization of MAP kinase phosphatase-2 in senescence of human fibroblasts.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209049

7 January 2021

Lack of Elk-1 phosphorylation and dysregulation of the extracellular regulated kinase signaling pathway in senescent human fibroblast.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209049

7 January 2021

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7 January 2021

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209049

7 January 2021

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209049

7 January 2021

Targeted histone deacetylase inhibition for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209049

7 January 2021

Replicative senescence of human endothelial cells in vitro involves G1 arrest, polyploidization and senescence-associated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209049

7 January 2021

Distinct mechanisms of cell cycle arrest control the decision between differentiation and senescence in human neuroblastoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209049

7 January 2021

Induction of senescent-like growth arrest as a new target in anticancer treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209049

7 January 2021

Cellular senescence as a tumor-protection mechanism: the essential role of counting

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209049

7 January 2021

S-nitrosylation-dependent inactivation of Akt/protein kinase B in insulin resistance.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209049

7 January 2021

Retinoic acid inhibition of cell cycle progression in MCF-7 human breast cancer cells

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209049

1 reference

24 December 2017

Dimensions Publication ID

0 references

1 reference

24 December 2017