(Q38335300)

English

Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis

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Europe PubMed Central

PubMed publication ID

2 September 2017

Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

1 reference

based on heuristic

inferred from title

3

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Peter van Sluis

6

object named as

Peter van Sluis

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Rogier Versteeg

object named as

Rogier Versteeg

8

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object named as

Jan Koster

5

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author name string

Derek M Murphy

1

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Patrick G Buckley

2

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Karen M Watters

4

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Jan Molenaar

7

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Raymond L Stallings

9

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

publication date

28 December 2010

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Europe PubMed Central

PubMed publication ID

2 September 2017

Molecular Carcinogenesis

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Europe PubMed Central

PubMed publication ID

2 September 2017

50

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Europe PubMed Central

PubMed publication ID

2 September 2017

6

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Europe PubMed Central

PubMed publication ID

2 September 2017

403-411

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Europe PubMed Central

PubMed publication ID

2 September 2017

Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Targeted expression of MYCN causes neuroblastoma in transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Sequence-specific transcriptional activation by Myc and repression by Max.

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

An alternative pathway for gene regulation by Myc

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

p53 is a direct transcriptional target of MYCN in neuroblastoma

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Global MYCN transcription factor binding analysis in neuroblastoma reveals association with distinct E-box motifs and regions of DNA hypermethylation

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1Bbeta and TSLC1 in neuroblastoma

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Cellular retinoic acid-binding protein II is a direct transcriptional target of MycN in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Widespread dysregulation of MiRNAs by MYCN amplification and chromosomal imbalances in neuroblastoma: association of miRNA expression with survival

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours.

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

MYCN regulates oncogenic MicroRNAs in neuroblastoma

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2.

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Differential patterns of microRNA expression in neuroblastoma are correlated with prognosis, differentiation, and apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors.

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Accurate prediction of neuroblastoma outcome based on miRNA expression profiles

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

MYCN oncoprotein targets and their therapeutic potential

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Altered expression of cell cycle genes distinguishes aggressive neuroblastoma

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

c-myc and N-myc promote active stem cell metabolism and cycling as architects of the developing brain

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Cell cycle regulation targets of MYCN identified by gene expression microarrays

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Cdc25 cell-cycle phosphatase as a target of c-myc

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Role of the Cdc25A phosphatase in human breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Rapid destruction of human Cdc25A in response to DNA damage

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Control of DNA replication: regulation and activation of eukaryotic replicative helicase, MCM

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Cdc6 knockdown inhibits human neuroblastoma cell proliferation

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Regulation of BIRC5 and its isoform BIRC5-2B in neuroblastoma

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state.

1 reference

https://api.crossref.org/works/10.1002%2FMC.20722

21 January 2018

Identifiers

10.1002/MC.20722

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

ResearchGate publication ID

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