(Q38339361)

2 September 2017

title

Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa (English)

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2 September 2017

1

Akira Sassa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078407

27 August 2024

author name string

Naoko Niimi

2

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2 September 2017

Hirofumi Fujimoto

3

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2 September 2017

Atsushi Katafuchi

4

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2 September 2017

Petr Grúz

5

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2 September 2017

Manabu Yasui

6

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2 September 2017

Francis Johnson

8

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2 September 2017

Toshihiro Ohta

9

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2 September 2017

Takehiko Nohmi

10

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2 September 2017

Ramesh C. Gupta

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078407

27 August 2024

language of work or name

English

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publication date

13 November 2010

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full work available at URL

2 September 2017

https://api.elsevier.com/content/article/PII:S1383571810003852?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.MRGENTOX.2010.11.002

https://api.elsevier.com/content/article/PII:S1383571810003852?httpAccept=text/plain

27 August 2024

1 reference

https://api.crossref.org/works/10.1016/J.MRGENTOX.2010.11.002

27 August 2024

1 reference

2 September 2017

volume

718

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2 September 2017

issue

1-2

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2 September 2017

page(s)

10-17

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Environmental stress and lesion-bypass DNA polymerases

2 September 2017

cites work

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Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function

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Translesion synthesis in mammalian cells

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Fidelity of human DNA polymerase eta

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The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

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Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta selectively produces a two-base deletion in copying the N2-guanyl adduct of 2-amino-3-methylimidazo[4,5-f]quinoline but not the C8 adduct at the NarI

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Polycyclic hydrocarbon activation: bay regions and beyond

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The steric gate amino acid tyrosine 112 is required for efficient mismatched-primer extension by human DNA polymerase kappa

27 August 2024

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Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).

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Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro

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trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases

27 August 2024

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Translesion synthesis across bulky N2-alkyl guanine DNA adducts by human DNA polymerase kappa

27 August 2024

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Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa.

27 August 2024

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Quantitative analysis of translesion DNA synthesis across a benzo[a]pyrene-guanine adduct in mammalian cells: the role of DNA polymerase kappa

27 August 2024

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Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene

27 August 2024

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Polk mutant mice have a spontaneous mutator phenotype

27 August 2024

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Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass

27 August 2024

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The N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions

27 August 2024

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Efficient synthesis of the benzo[a]pyrene metabolic adducts of 2'-deoxyguanosine and 2'-deoxyadenosine and their direct incorporation into DNA.

27 August 2024

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Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases

27 August 2024

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Quantitation of base substitutions and deletions induced by chemical mutagens during DNA synthesis in vitro.

27 August 2024

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Miscoding properties of 3,N4-etheno-2'-deoxycytidine in reactions catalyzed by mammalian DNA polymerases

27 August 2024

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27 August 2024

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Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove

27 August 2024

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Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction

27 August 2024

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DNA polymerase action on benzo[a]pyrene-DNA adducts

27 August 2024

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Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells

27 August 2024

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Efficient and accurate bypass of N2-(1-carboxyethyl)-2'-deoxyguanosine by DinB DNA polymerase in vitro and in vivo.

27 August 2024

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Extensive chromosomal breaks are induced by tamoxifen and estrogen in DNA repair-deficient cells

27 August 2024

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Error-free replicative bypass of thymine glycol by the combined action of DNA polymerases kappa and zeta in human cells

27 August 2024

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27 August 2024

Identifiers

1 reference

2 September 2017

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