(Q38340001)

2 September 2017

title

Altered insulin signaling in retinal tissue in diabetic states (English)

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2 September 2017

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2

C Ronald Kahn

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2 September 2017

1

Tatsuya Kondo

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2 September 2017

language of work or name

English

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publication date

16 June 2004

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

279

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2 September 2017

issue

36

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2 September 2017

page(s)

37997-38006

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UKPDS 59: hyperglycemia and other potentially modifiable risk factors for peripheral vascular disease in type 2 diabetes.

2 September 2017

cites work

1 reference

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Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin.

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Insulin stimulates both endothelin and nitric oxide activity in the human forearm.

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Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization

21 January 2018

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Markers of insulin resistance are strong risk factors for retinopathy incidence in type 1 diabetes

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Insulin signalling and the regulation of glucose and lipid metabolism

21 January 2018

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Functions of insulin and insulin receptor signaling in retina: possible implications for diabetic retinopathy

21 January 2018

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Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus

21 January 2018

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Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: potential role of p38 in the downregulation of GLUT4 expression.

21 January 2018

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Insulin resistance in diabetic microangiopathies.

21 January 2018

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Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance

21 January 2018

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Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats

21 January 2018

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Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

21 January 2018

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Effects of STZ-Induced Diabetes and Fasting on Insulin Receptor mRNA Expression and Insulin Receptor Gene Transcription in Rat Liver

21 January 2018

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Regulation of IRS-2 tyrosine phosphorylation in fasting and diabetes

21 January 2018

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Differential Expression of Retinal Insulin Receptors in STZ-Induced Diabetic Rats

21 January 2018

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Insulin resistance is mediated by a proteolytic fragment of the insulin receptor

21 January 2018

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Control of insulin receptor level in 3T3 cells: effect of insulin-induced down-regulation and dexamethasone-induced up-regulation on rate of receptor inactivation

21 January 2018

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A monoclonal antibody to visualize PtdIns(3,4,5)P(3) in cells

21 January 2018

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Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia

21 January 2018

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Immunocytochemical detection of phosphatidylinositol 3-kinase activation by insulin and leptin

21 January 2018

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A new molecular target of insulin action: regulating the pivotal PDK1.

21 January 2018

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MKK6/3 and p38 MAPK pathway activation is not necessary for insulin-induced glucose uptake but regulates glucose transporter expression

21 January 2018

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Insulin signals to prenyltransferases via the Shc branch of intracellular signaling

21 January 2018

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Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells

21 January 2018

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Endothelial response to hypoxia: physiologic adaptation and pathologic dysfunction

21 January 2018

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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

21 January 2018

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Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

21 January 2018

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The Akt kinase signals directly to endothelial nitric oxide synthase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M401339200

1 reference

2 September 2017

1 reference