(Q38343221)

English

Humanization of a mouse monoclonal antibody directed against a cell surface-exposed epitope of membrane-associated heat shock protein 70 (Hsp70).

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

2 September 2017

Humanization of a mouse monoclonal antibody directed against a cell surface-exposed epitope of membrane-associated heat shock protein 70 (Hsp70). (English)

1 reference

Europe PubMed Central

2 September 2017

Roland E Kontermann

4

object named as

Roland E Kontermann

1 reference

Europe PubMed Central

2 September 2017

author name string

Kirstin A Zettlitz

1

1 reference

Europe PubMed Central

2 September 2017

Julia Seitter

2

1 reference

Europe PubMed Central

2 September 2017

Dafne Müller

3

1 reference

Europe PubMed Central

2 September 2017

publication date

1 November 2010

1 reference

Europe PubMed Central

2 September 2017

Molecular Biotechnology

1 reference

Europe PubMed Central

2 September 2017

46

1 reference

Europe PubMed Central

2 September 2017

3

1 reference

Europe PubMed Central

2 September 2017

265-278

1 reference

Europe PubMed Central

2 September 2017

https://scigraph.springernature.com/pub.10.1007/s12033-010-9298-x

0 references

Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages.

1 reference

https://api.crossref.org/works/10.1007%2FS12033-010-9298-X

21 January 2018

Heat shock protein 70 (Hsp70) membrane expression on head-and-neck cancer biopsy-a target for natural killer (NK) cells.

1 reference

https://api.crossref.org/works/10.1007%2FS12033-010-9298-X

21 January 2018

The cell surface-localized heat shock protein 70 epitope TKD induces migration and cytolytic activity selectively in human NK cells.

1 reference

https://api.crossref.org/works/10.1007%2FS12033-010-9298-X

21 January 2018

N-glycosylation as novel strategy to improve pharmacokinetic properties of bispecific single-chain diabodies

1 reference

https://api.crossref.org/works/10.1007%2FS12033-010-9298-X

21 January 2018

Engineering antibodies for stability and efficient folding.

1 reference

https://api.crossref.org/works/10.1007%2FS12033-010-9298-X

21 January 2018

Antibody variable region glycosylation: biochemical and clinical effects

1 reference

https://api.crossref.org/works/10.1007%2FS12033-010-9298-X

21 January 2018

Structural families in loops of homologous proteins: automatic classification, modelling and application to antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Framework shuffling of antibodies to reduce immunogenicity and manipulate functional and biophysical properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patient survival by Hsp70 membrane phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analyzing the "degree of humanness" of antibody sequences.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of natural killer cells by heat shock protein 70. 2002.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential up-regulation of cytosolic and membrane-bound heat shock protein 70 in tumor cells by anti-inflammatory drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A stress-inducible 72-kDa heat-shock protein (HSP72) is expressed on the surface of human tumor cells, but not on normal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-expression of Skp and FkpA chaperones improves cell viability and alters the global expression of stress response genes during scFvD1.3 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular engineering and design of therapeutic antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Engineering of therapeutic antibodies to minimize immunogenicity and optimize function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The heat-shock proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved pharmacokinetics of recombinant bispecific antibody molecules by fusion to human serum albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adoptive transfer of human natural killer cells in mice with severe combined immunodeficiency inhibits growth of Hsp70-expressing tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Engineering therapeutic monoclonal antibodies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunogenicity of engineered antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chimeric and humanized antibodies with specificity for the CD33 antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 14-mer Hsp70 peptide stimulates natural killer (NK) cell activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strategies to extend plasma half-lives of recombinant antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane-bound heat shock protein 70 (Hsp70) in acute myeloid leukemia: a tumor specific recognition structure for the cytolytic activity of autologous NK cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent antibody therapeutics by design

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The periplasmic Escherichia coli peptidylprolyl cis,trans-isomerase FkpA. I. Increased functional expression of antibody fragments with and without cis-prolines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzyme immunoassays using bispecific diabodies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock protein 70 (Hsp70): membrane location, export and immunological relevance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Definition of extracellular localized epitopes of Hsp70 involved in an NK immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Message in a bottle: role of the 70-kDa heat shock protein family in anti-tumor immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock protein 70 membrane expression and melanoma-associated marker phenotype in primary and metastatic melanoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock proteins in cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hsp70 plasma membrane expression on primary tumor biopsy material and bone marrow of leukemic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bacterial production and functional characterization of the Fab fragment of the murine IgG1/lambda monoclonal antibody cmHsp70.1, a reagent for tumour diagnostics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of colon and lung cancer patients with ex vivo heat shock protein 70-peptide-activated, autologous natural killer cells: a clinical phase i trial.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock protein 72 on tumor cells: a recognition structure for natural killer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selecting and screening recombinant antibody libraries

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Humanization of an anti-p185HER2 antibody for human cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Humanization of antibodies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetically engineered deglycosylation of the variable domain increases the affinity of an anti-CD33 monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improving effector functions of antibodies for cancer treatment: Enhancing ADCC and CDC

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High HSP70-membrane expression on leukemic cells from patients with acute myeloid leukemia is associated with a worse prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of tumor growth in mice with severe combined immunodeficiency is mediated by heat shock protein 70 (Hsp70)-peptide-activated, CD94 positive natural killer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hsp70 chaperones: cellular functions and molecular mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody engineering for the development of therapeutic antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20556545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12033-010-9298-X

1 reference

Europe PubMed Central

2 September 2017

1 reference

Europe PubMed Central

2 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q38343221&oldid=1598655638"