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Identification of a consensus element recognized and cleaved by IRE1 alpha.
scientific article published on 27 May 2010
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scholarly article
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Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
title
Identification of a consensus element recognized and cleaved by IRE1 alpha
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
author
Takao Iwawaki
series ordinal
4
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Europe PubMed Central
PMCID
2952871
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
author name string
Daisuke Oikawa
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1
1 reference
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Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
Mio Tokuda
series ordinal
2
1 reference
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Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
Akira Hosoda
series ordinal
3
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stated in
Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
language of work or name
English
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publication date
27 May 2010
1 reference
stated in
Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
published in
Nucleic Acids Research
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stated in
Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
volume
38
1 reference
stated in
Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
page(s)
6265-6273
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Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
issue
18
1 reference
stated in
Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
copyright license
Creative Commons Attribution-NonCommercial 2.5 Generic
start time
4 October 2016
1 reference
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April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
Site-specific cleavage of CD59 mRNA by endoplasmic reticulum-localized ribonuclease, IRE1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
The mammalian unfolded protein response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
Cloning of mammalian Ire1 reveals diversity in the ER stress responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
6 September 2017
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
14 September 2017
Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
14 September 2017
The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
23 June 2018
Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
31 August 2018
Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
31 August 2018
Analysis of the XBP1 splicing mechanism using endoplasmic reticulum stress-indicators.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952871
retrieved
31 August 2018
Identifiers
DOI
10.1093/NAR/GKQ452
1 reference
stated in
Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
PMCID
2952871
1 reference
stated in
Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
PubMed ID
20507909
1 reference
stated in
Europe PubMed Central
PMCID
2952871
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20507909%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 February 2020
ResearchGate publication ID
44635521
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