(Q38346151)

2 September 2017

title

Deficiency of the splicing factor Sfrs10 results in early embryonic lethality in mice and has no impact on full-length SMN/Smn splicing (English)

1 reference

2 September 2017

Markus Riessland

3

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Thorsten Buch

object named as

Thorsten Buch

8

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André Kleinridders

object named as

André Kleinridders

6

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author name string

Ylva Mende

1

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2 September 2017

Miriam Jakubik

2

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2 September 2017

Frank Schoenen

4

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2 September 2017

Kristina Rossbach

5

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2 September 2017

Christoph Köhler

7

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2 September 2017

Brunhilde Wirth

9

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2 September 2017

language of work or name

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27 February 2010

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2 September 2017

published in

Human Molecular Genetics

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2 September 2017

volume

19

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2 September 2017

issue

11

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2 September 2017

page(s)

2154-2167

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Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing

2 September 2017

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A sequence-specific splicing activator, tra2beta, is up-regulated in response to nerve injury

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Expression of a novel RNA-splicing factor, RA301/Tra2beta, in vascular lesions and its role in smooth muscle cell proliferation

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Function of alternative splicing

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Human tra2-beta1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA.

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Tra2betal regulates P19 neuronal differentiation and the splicing of FGF-2R and GluR-B minigenes

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Regulation of the neuron-specific exon of clathrin light chain B.

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Tra2beta as a novel mediator of vascular smooth muscle diversification

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Up-regulation of the ubiquitous alternative splicing factor Tra2beta causes inclusion of a germ cell-specific exon

21 January 2018

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RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing

21 January 2018

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Mutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 beta

21 January 2018

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Tra2 beta, SF2/ASF and SRp30c modulate the function of an exonic splicing enhancer in exon 10 of tau pre-mRNA

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Restoration of the cystic fibrosis transmembrane conductance regulator function by splicing modulation

21 January 2018

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Alternative splicing of fibroblast growth factor receptors in human prostate cancer

21 January 2018

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Htra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2)

21 January 2018

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hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1

21 January 2018

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Identification and characterization of a spinal muscular atrophy-determining gene

21 January 2018

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Structure and organization of the human survival motor neurone (SMN) gene

21 January 2018

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Quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy

21 January 2018

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When is a deletion not a deletion? When it is converted

21 January 2018

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Mildly affected patients with spinal muscular atrophy are partially protected by an increased SMN2 copy number

21 January 2018

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A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

21 January 2018

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Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1.

21 January 2018

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SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1

21 January 2018

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TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing

21 January 2018

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Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy

21 January 2018

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The benzamide M344, a novel histone deacetylase inhibitor, significantly increases SMN2 RNA/protein levels in spinal muscular atrophy cells

21 January 2018

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Spinal muscular atrophy: from gene to therapy

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Valproic acid increases SMN levels in spinal muscular atrophy patient cells.

21 January 2018

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SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy

21 January 2018

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Sex in flies: the splice of life

21 January 2018

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High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

21 January 2018

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A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

21 January 2018

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Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes

21 January 2018

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Complete nucleotide sequence, genomic organization, and promoter analysis of the murine survival motor neuron gene (Smn).

21 January 2018

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Cloning, characterization, and copy number of the murine survival motor neuron gene: homolog of the spinal muscular atrophy-determining gene

21 January 2018

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Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity

21 January 2018

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A mouse model for spinal muscular atrophy

21 January 2018

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Animal models of spinal muscular atrophy

21 January 2018

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LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate

21 January 2018

1 reference

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Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20.

21 January 2018

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ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle

21 January 2018

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SC35 plays a role in T cell development and alternative splicing of CD45.

21 January 2018

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hnRNP C is required for postimplantation mouse development but Is dispensable for cell viability

21 January 2018

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Dephosphorylation-dependent sorting of SR splicing factors during mRNP maturation.

21 January 2018

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Regulation of murine survival motor neuron (Smn) protein levels by modifying Smn exon 7 splicing

21 January 2018

1 reference

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Bifunctional antisense oligonucleotides provide a trans-acting splicing enhancer that stimulates SMN2 gene expression in patient fibroblasts

21 January 2018

1 reference

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Correction of disease-associated exon skipping by synthetic exon-specific activators

21 January 2018

1 reference

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Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation

21 January 2018

1 reference

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The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria

21 January 2018

1 reference

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Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation

21 January 2018

1 reference

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Simplified mammalian DNA isolation procedure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ094

21 January 2018

Identifiers

DOI

10.1093/HMG/DDQ094

1 reference

2 September 2017

1 reference