(Q38348145)

2 September 2017

title

Evidence for a key role of leptin in osteoarthritis (English)

1 reference

2 September 2017

0 references

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31 March 2024

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31 March 2024

1

Hélène Dumond

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14613274

31 March 2024

author name string

Nathalie Presle

2

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2 September 2017

Bernard Terlain

3

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2 September 2017

Didier Mainard

4

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2 September 2017

Damien Loeuille

5

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2 September 2017

Patrick Netter

6

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2 September 2017

Pascale Pottie

7

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2 September 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14613274

31 March 2024

publication date

1 November 2003

1 reference

full work available at URL

2 September 2017

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/art.11303

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14613274

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fart.11303

31 March 2024

1 reference

https://onlinelibrary.wiley.com/doi/pdf/10.1002/art.11303

31 March 2024

1 reference

31 March 2024

published in

Arthritis & Rheumatology

1 reference

2 September 2017

Arthritis and Rheumatism

48

11

3118–29

November 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14613274

31 March 2024

volume

48

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2 September 2017

issue

11

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2 September 2017

page(s)

3118-3129

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Human obese gene expression. Adipocyte-specific expression and regional differences in the adipose tissue

2 September 2017

cites work

1

1 reference

Positional cloning of the mouse obese gene and its human homologue

31 March 2024

2

1 reference

Effects of the obese gene product on body weight regulation in ob/ob mice

31 March 2024

3

1 reference

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

31 March 2024

4

1 reference

Identification of targets of leptin action in rat hypothalamus

31 March 2024

5

1 reference

Weight-reducing effects of the plasma protein encoded by the obese gene

31 March 2024

6

1 reference

Identification and expression cloning of a leptin receptor, OB-R

31 March 2024

7

1 reference

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

31 March 2024

8

1 reference

Defective STAT signaling by the leptin receptor in diabetic mice

31 March 2024

9

1 reference

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

31 March 2024

10

1 reference

Leptin regulation of the immune response and the immunodeficiency of malnutrition

31 March 2024

11

1 reference

Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization

31 March 2024

12

1 reference

Leptin and its role in lipid metabolism

31 March 2024

13

1 reference

Early onset of reproductive function in normal female mice treated with leptin

31 March 2024

14

1 reference

Leptin actions on food intake and body temperature are mediated by IL-1

31 March 2024

15

1 reference

Biological action of leptin as an angiogenic factor

31 March 2024

16

1 reference

Leptin is an endogenous protective protein against the toxicity exerted by tumor necrosis factor

31 March 2024

19

1 reference

Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

31 March 2024

20

1 reference

Leptin regulates bone formation via the sympathetic nervous system

31 March 2024

21

1 reference

Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic signaling

31 March 2024

22

1 reference

31 March 2024

Leptin: brains and bones

23

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Potential role of leptin in endochondral ossification

31 March 2024

24

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Human articular chondrocytes express functional leptin receptors

31 March 2024

25

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The interleukin-1 receptor in normal and osteoarthritic human articular chondrocytes. Identification as the type I receptor and analysis of binding kinetics and biologic function

31 March 2024

26

1 reference

Cytokines in osteoarthritis: mediators or markers of joint destruction?

31 March 2024

27

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Chondrocyte tumor necrosis factor receptors and focal loss of cartilage in osteoarthritis

31 March 2024

28

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The role of cytokines as inflammatory mediators in osteoarthritis: lessons from animal models

31 March 2024

29

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In vivo and in vitro stimulation of chondrocyte biosynthetic activity in early experimental osteoarthritis

31 March 2024

31

1 reference

Insulin-like growth factors maintain steady-state metabolism of proteoglycans in bovine articular cartilage explants

31 March 2024

32

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Chondrocyte cytokine and growth factor expression in murine osteoarthritis.

31 March 2024

33

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In vivo protection against interleukin-1-induced articular cartilage damage by transforming growth factor-beta 1: age-related differences

31 March 2024

35

1 reference

Body mass indices in patients with disabling hip osteoarthritis

31 March 2024

36

1 reference

Body Weight, Body Mass Index, and Incident Symptomatic Osteoarthritis of the Hand, Hip, and Knee

31 March 2024

38

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Gender differences in serum leptin levels in humans

31 March 2024

41

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Suppression of cartilage matrix gene expression in upper zone chondrocytes of osteoarthritic cartilage

31 March 2024

42

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Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-beta injections

31 March 2024

43

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Leptin is a potent stimulator of bone growth in ob/ob mice

31 March 2024

44

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Leptin acts as a growth factor on the chondrocytes of skeletal growth centers

31 March 2024

45

1 reference

IGF and IGF-binding protein system in the synovial fluid of osteoarthritic and rheumatoid arthritic patients.

31 March 2024

46

1 reference

Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and seronegative spondylarthropathies

31 March 2024

47

1 reference

Insulin-like growth factor (IGF) receptor, IGF-I, interleukin-1 beta (IL-1 beta), and IL-6 mRNA expression in osteoarthritic and normal human cartilage

31 March 2024

48

1 reference

Modulation of collagenase 3 in human osteoarthritic cartilage by activation of extracellular transforming growth factor beta: role of furin convertase

31 March 2024

50

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Inhibition of endogenous TGF-beta during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair

31 March 2024

51

1 reference

Recent advances in TGF-beta effects on chondrocyte metabolism. Potential therapeutic roles of TGF-beta in cartilage disorders.

31 March 2024

53

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Effect of transforming growth factor-beta and platelet-derived growth factor-BB on articular cartilage in rats

31 March 2024

54

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Effects of interleukin-1 beta on insulin-like growth factor-I autocrine/paracrine axis in cultured rat articular chondrocytes

31 March 2024

55

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Prostaglandin E2 stimulates incorporation of proline into collagenase digestible proteins in human articular chondrocytes: identification of an effector autocrine loop involving insulin-like growth factor I

31 March 2024

56

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Osteoblasts and osteoclasts in adult human osteophyte tissue express the mRNAs for insulin-like growth factors I and II and the type 1 IGF receptor

31 March 2024

57

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Expression of insulin-like growth factor I messenger ribonucleic acid in developing osteophytes in murine experimental osteoarthritis and in rats inoculated with growth hormone-secreting tumor

31 March 2024

58

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Growth factor expression in the osteophytes of the human femoral head in osteoarthritis

31 March 2024

59

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Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation

31 March 2024

60

1 reference

Differential expression of collagen types I, II, III, and X in human osteophytes

31 March 2024

61

1 reference

Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta

31 March 2024

62

1 reference

Binding of a pure 125I-monoiodoleptin analog to mouse tissues: a developmental study

31 March 2024

63

1 reference

Osteoarthritis as a systemic disorder including stromal cell differentiation and lipid metabolism

31 March 2024

64

1 reference

31 March 2024

Identifiers

DOI

10.1002/ART.11303

1 reference

2 September 2017

1 reference