(Q38349558)

2 September 2017

RNA cleaving '10-23' DNAzymes with enhanced stability and activity (English)

1 reference

https://api.crossref.org/works/10.1093/NAR/GKG791

2 September 2017

1 reference

18 March 2024

author name string

Steffen Schubert

1

1 reference

2 September 2017

Hans-Peter Grunert

3

1 reference

2 September 2017

Heinz Zeichhardt

4

1 reference

2 September 2017

Jens Kurreck

6

1 reference

2 September 2017

Deniz C. Gül

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14530446

18 March 2024

Volker A. Erdmann

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14530446

18 March 2024

language of work or name

English

0 references

publication date

1 October 2003

1 reference

2 September 2017

15 October 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14530446

full work available at URL

18 March 2024

https://academic.oup.com/nar/article-pdf/31/20/5982/6257273/gkg791.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14530446

https://europepmc.org/articles/PMC219472

18 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14530446

https://europepmc.org/articles/PMC219472?pdf=render

18 March 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14530446

https://doi.org/10.1093/nar/gkg791

18 March 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14530446

http://academic.oup.com/nar/article-pdf/31/20/5982/6257273/gkg791.pdf

18 March 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1093/NAR/GKG791

18 March 2024

published in

Nucleic Acids Research

1 reference

2 September 2017

31

1 reference

2 September 2017

20

1 reference

2 September 2017

5982-5992

1 reference

Antisense technologies. Improvement through novel chemical modifications

2 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

LNA: a versatile tool for therapeutics and genomics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

DNAzymes: cutting a path to a new class of therapeutics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Comparative study of DNA enzymes and ribozymes against the same full-length messenger RNA of the vanilloid receptor subtype I.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

DNAzymes to beta 1 and beta 3 mRNA down-regulate expression of the targeted integrins and inhibit endothelial cell capillary tube formation in fibrin and matrigel

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

The influence of arm length asymmetry and base substitution on the activity of the 10-23 DNA enzyme.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Structural studies of LNA:RNA duplexes by NMR: conformations and implications for RNase H activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Potent and nontoxic antisense oligonucleotides containing locked nucleic acids

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Nucleic acid mutation analysis using catalytic DNA.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Progress in antisense technology: the end of the beginning

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Mechanism and utility of an RNA-cleaving DNA enzyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Effects of helical structures formed by the binding arms of DNAzymes and their substrates on catalytic activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

The capsaicin receptor: a heat-activated ion channel in the pain pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

A general purpose RNA-cleaving DNA enzyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Design of antisense oligonucleotides stabilized by locked nucleic acids

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Optimisation of the 10-23 DNAzyme-substrate pairing interactions enhanced RNA cleavage activity at purine-cytosine target sites

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

LNAzymes: incorporation of LNA-type monomers into DNAzymes markedly increases RNA cleavage.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Angiogenic inhibition mediated by a DNAzyme that targets vascular endothelial growth factor receptor 2.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Sequence requirements in the catalytic core of the "10-23" DNA enzyme

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

DNA enzyme targeting TNF-alpha mRNA improves hemodynamic performance in rats with postinfarction heart failure.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

RNA cleavage by the 10-23 DNA enzyme.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Design of nuclease resistant protein kinase calpha DNA enzymes with potential therapeutic application.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Inhibition of bcr-abl oncogene expression by novel deoxyribozymes (DNAzymes).

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

Sequence-specific cleavage of Huntingtin mRNA by catalytic DNA.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=219472

New DNA enzyme targeting Egr-1 mRNA inhibits vascular smooth muscle proliferation and regrowth after injury

31 August 2018

1 reference

12 December 2020

Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance

1 reference

12 December 2020

Extremely high and specific activity of DNA enzymes in cells with a Philadelphia chromosome

1 reference

12 December 2020

Suppression of smooth muscle cell proliferation by a c-myc RNA-cleaving deoxyribozyme

1 reference

12 December 2020

Targeting Raf-1 gene expression by a DNA enzyme inhibits juvenile myelomonocytic leukemia cell growth

1 reference

12 December 2020

Cellular uptake, distribution, and stability of 10-23 deoxyribozymes

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKG791

1 reference

2 September 2017

1 reference

2 September 2017

1 reference