(Q38350251)

2 September 2017

title

Leptin regulates leukocyte recruitment into the brain following systemic LPS-induced inflammation (English)

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2 September 2017

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C Rummel

1

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2 September 2017

W Inoue

series ordinal

2

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2 September 2017

S Poole

series ordinal

3

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2 September 2017

G N Luheshi

series ordinal

4

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2 September 2017

language of work or name

English

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publication date

22 September 2009

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2 September 2017

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2 September 2017

volume

15

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2 September 2017

issue

5

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2 September 2017

page(s)

523-534

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https://scigraph.springernature.com/pub.10.1038/mp.2009.98

2 September 2017

exact match

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cites work

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Impairment of host resistance to Listeria monocytogenes infection in liver of db/db and ob/ob mice

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Leptin-deficient mice exhibit impaired host defense in Gram-negative pneumonia

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Requirement for leptin in the induction and progression of autoimmune encephalomyelitis.

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Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis

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Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

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Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice

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Leptin actions on food intake and body temperature are mediated by IL-1

21 January 2018

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Circulating leptin mediates lipopolysaccharide-induced anorexia and fever in rats

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Leptin regulates interleukin-1beta expression in the brain via the STAT3-independent mechanisms

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Interleukin-6 and leptin mediate lipopolysaccharide-induced fever and sickness behavior.

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Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia

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Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters

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Physiological regulation of hypothalamic IL-1beta gene expression by leptin and glucocorticoids: implications for energy homeostasis

21 January 2018

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Leptin induces cyclooxygenase-2 via an interaction with interleukin-1beta in the rat brain.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Selective contribution of interleukin-6 and leptin to brain inflammatory signals induced by systemic LPS injection in mice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Immunohistochemical evidence of functional leptin receptor expression in neuronal and endothelial cells of the rat brain.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

21 January 2018

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Appearance of interleukin-1 in macrophages and in ramified microglia in the brain of endotoxin-treated rats: a pathway for the induction of non-specific symptoms of sickness?

21 January 2018

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Time course and localization patterns of interleukin-1beta messenger RNA expression in brain and pituitary after peripheral administration of lipopolysaccharide

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Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1 expression in the brain.

21 January 2018

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Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration.

21 January 2018

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Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism

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High serum levels of leptin are associated with post-stroke depression.

21 January 2018

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Inflammatory and injury responses to ischemic stroke in obese mice

21 January 2018

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Systemic LPS injection leads to granulocyte influx into normal and injured brain: effects of ICAM-1 deficiency

21 January 2018

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The unique characteristics of inflammatory responses in mouse brain are acquired during postnatal development.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

21 January 2018

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Persistent macrophage/microglial activation and myelin disruption after experimental autoimmune encephalomyelitis in tissue inhibitor of metalloproteinase-1-deficient mice

21 January 2018

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Apoptotic pathways are inhibited by leptin receptor activation in neutrophils.

21 January 2018

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Interleukin-1 and neuronal injury

21 January 2018

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CXC chemokines generate age-related increases in neutrophil-mediated brain inflammation and blood-brain barrier breakdown

21 January 2018

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Intracerebroventricular but not intravenous interleukin-1beta induces widespread vascular-mediated leukocyte infiltration and immune signal mRNA expression followed by brain-wide glial activation

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IL-1 type I receptor plays a key role in mediating the recruitment of leukocytes into the central nervous system

21 January 2018

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Central origin of IL-1beta produced during peripheral inflammation: role of meninges.

21 January 2018

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Rat brain vascular distribution of interleukin-1 type-1 receptor immunoreactivity: relationship to patterns of inducible cyclooxygenase expression by peripheral inflammatory stimuli

21 January 2018

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Type 1 interleukin-1 receptor in the rat brain: distribution, regulation, and relationship to sites of IL-1-induced cellular activation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Systemic inflammatory stimulus potentiates the acute phase and CXC chemokine responses to experimental stroke and exacerbates brain damage via interleukin-1- and neutrophil-dependent mechanisms

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Peripheral inflammation exacerbates damage after global ischemia independently of temperature and acute brain inflammation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

CXC chemokine receptor-2 ligands are required for neutrophil-mediated host defense in experimental brain abscesses.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Leptin induces an Apc genotype-associated colon epithelial cell chemokine production pattern associated with macrophage chemotaxis and activation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Leptin corrects host defense defects after acute starvation in murine pneumococcal pneumonia.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Reduced leptin levels in starvation increase susceptibility to endotoxic shock

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Influence of feeding status on neuronal activity in the hypothalamus during lipopolysaccharide-induced anorexia in rats.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Neonatal immune challenge does not affect body weight regulation in rats.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Fever response in lean (Fa/-) and obese (fa/fa) Zucker rats and its lack to repeated injections of LPS.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

CCK(2) receptor nullification attenuates lipopolysaccharide-induced sickness behavior.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Permeability of the blood-brain barrier depends on brain temperature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.98

Systemic infections and inflammation affect chronic neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Cerebral microglia recruit monocytes into the brain in response to tumor necrosis factoralpha signaling during peripheral organ inflammation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Induction of Neutrophil Chemotaxis by Leptin: Crucial Role for p38 and Src Kinases

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

Cell-mediated immunity in genetically obese C57BL/6J ob/ob) mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2009.98

7 January 2021

Expression of leptin receptor isoforms in rat brain microvessels

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.98

7 January 2021

Chronic interleukin-1beta expression in mouse brain leads to leukocyte infiltration and neutrophil-independent blood brain barrier permeability without overt neurodegeneration

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.98

7 January 2021

The role of leptin in regulating neuroendocrine function in humans

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.98

7 January 2021

The bacterial endotoxin lipopolysaccharide has the ability to target the brain in upregulating its membrane CD14 receptor within specific cellular populations

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.98

7 January 2021

A new function of the leptin receptor: mediation of the recovery from lipopolysaccharide-induced hypothermia

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.98

7 January 2021

Expression of interleukin 1 alpha and beta, and interleukin 1 receptor antagonist mRNA in the rat central nervous system after peripheral administration of lipopolysaccharides

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.98

7 January 2021

IL-6 and IL-1 beta in fever. Studies using cytokine-deficient (knockout) mice

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.98

7 January 2021

Identifiers

DOI

10.1038/MP.2009.98

1 reference

2 September 2017

1 reference