(Q38351980)

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Complementary functions of the Saccharomyces cerevisiae Rad2 family nucleases in Okazaki fragment maturation, mutation avoidance, and chromosome stability

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scholarly article

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Europe PubMed Central

2 September 2017

Complementary functions of the Saccharomyces cerevisiae Rad2 family nucleases in Okazaki fragment maturation, mutation avoidance, and chromosome stability (English)

1 reference

Europe PubMed Central

2 September 2017

Saccharomyces cerevisiae

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author name string

Xuemin Sun

1

1 reference

Europe PubMed Central

2 September 2017

Douglas Thrower

2

1 reference

Europe PubMed Central

2 September 2017

Junzhuan Qiu

3

1 reference

Europe PubMed Central

2 September 2017

Phillis Wu

4

1 reference

Europe PubMed Central

2 September 2017

Li Zheng

5

1 reference

Europe PubMed Central

2 September 2017

Mian Zhou

6

1 reference

Europe PubMed Central

2 September 2017

Jeff Bachant

7

1 reference

Europe PubMed Central

2 September 2017

David M Wilson

8

1 reference

Europe PubMed Central

2 September 2017

Binghui Shen

9

1 reference

Europe PubMed Central

2 September 2017

publication date

1 August 2003

1 reference

Europe PubMed Central

2 September 2017

1 reference

Europe PubMed Central

2 September 2017

2

1 reference

Europe PubMed Central

2 September 2017

8

1 reference

Europe PubMed Central

2 September 2017

925-940

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Europe PubMed Central

2 September 2017

The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair

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A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction.

1 reference

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7 January 2021

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Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1

1 reference

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XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair

1 reference

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7 January 2021

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Human xeroderma pigmentosum group G gene encodes a DNA endonuclease

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How nucleotide excision repair protects against cancer

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Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome

1 reference

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Enzymes and reactions at the eukaryotic DNA replication fork

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Flap endonuclease homologs in archaebacteria exist as independent proteins.

1 reference

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Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro

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Enzymatic completion of mammalian lagging-strand DNA replication

1 reference

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7 January 2021

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The characterization of a mammalian DNA structure-specific endonuclease

1 reference

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Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair

1 reference

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Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen

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7 January 2021

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Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA.

1 reference

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The Werner syndrome protein is a DNA helicase

1 reference

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7 January 2021

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Stimulation of eukaryotic flap endonuclease-1 activities by proliferating cell nuclear antigen (PCNA) is independent of its in vitro interaction via a consensus PCNA binding region

1 reference

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7 January 2021

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Cell cycle-dependent and DNA damage-inducible nuclear localization of FEN-1 nuclease is consistent with its dual functions in DNA replication and repair

1 reference

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7 January 2021

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Defective flap endonuclease 1 activity in mammalian cells is associated with impaired DNA repair and prolonged S phase delay

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

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Human RAD2 homolog 1 5'- to 3'-exo/endonuclease can efficiently excise a displaced DNA fragment containing a 5'-terminal abasic lesion by endonuclease activity

1 reference

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7 January 2021

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Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

1 reference

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7 January 2021

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A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

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Involvement of flap endonuclease 1 in base excision DNA repair.

1 reference

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7 January 2021

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A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair

1 reference

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7 January 2021

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Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA.

1 reference

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7 January 2021

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Expansion and length-dependent fragility of CTG repeats in yeast

1 reference

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7 January 2021

based on heuristic

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The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities

1 reference

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7 January 2021

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Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae

1 reference

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7 January 2021

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Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro

1 reference

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7 January 2021

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Homologous recombination is required for the viability of rad27 mutants

1 reference

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7 January 2021

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Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae

1 reference

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7 January 2021

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The interaction of DNA mismatch repair proteins with human exonuclease I

1 reference

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Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2

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Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis

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exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair

1 reference

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7 January 2021

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inferred from DOI database lookup

Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Human exonuclease I is required for 5' and 3' mismatch repair

1 reference

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Germline mutations of EXO1 gene in patients with hereditary nonpolyposis colorectal cancer (HNPCC) and atypical HNPCC forms

1 reference

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7 January 2021

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inferred from DOI database lookup

XPG protein has a structure-specific endonuclease activity

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidance

1 reference

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7 January 2021

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Conditional lethality of null mutations in RTH1 that encodes the yeast counterpart of a mammalian 5'- to 3'-exonuclease required for lagging strand DNA synthesis in reconstituted systems

1 reference

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7 January 2021

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inferred from DOI database lookup

Characterization of a mutant strain of Saccharomyces cerevisiae with a deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in RAD27 define a potential link between G1 cyclins and DNA replication

1 reference

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Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization

1 reference

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7 January 2021

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Multifunctional yeast high-copy-number shuttle vectors

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

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Suppression of Saccharomyces cerevisiae rad27 null mutant phenotypes by the 5' nuclease domain of Escherichia coli DNA polymerase I.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

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inferred from DOI database lookup

Genetic analysis of the in vivo role of DNA polymerases in Saccharomyces cerevisiae

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Semi-conservative replication in yeast nuclear extracts requires Dna2 helicase and supercoiled template.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The distribution of the numbers of mutants in bacterial populations

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

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Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

DNA polymerases delta and epsilon are required for chromosomal replication in Saccharomyces cerevisiae

1 reference

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7 January 2021

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Visual assay for chromosome ploidy

1 reference

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7 January 2021

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inferred from DOI database lookup

Mutator specificity and disease: looking over the FENce

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Dna2 of Saccharomyces cerevisiae possesses a single-stranded DNA-specific endonuclease activity that is able to act on double-stranded DNA in the presence of ATP.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the Enzymatic Properties of the Yeast Dna2 Helicase/Endonuclease Suggests a New Model for Okazaki Fragment Processing

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The nuclease activity of the yeast DNA2 protein, which is related to the RecB-like nucleases, is essential in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The pattern of sensitivity of yeast dna2 mutants to DNA damaging agents suggests a role in DSB and postreplication repair pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

The endonuclease activity of the yeast Dna2 enzyme is essential in vivo

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of yeast Rth1 nuclease and its homologs in mutation avoidance, DNA repair, and DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Saccharomyces cerevisiae exonuclease-1 plays a role in UV resistance that is distinct from nucleotide excision repair

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Proliferating Cell Nuclear Antigen Facilitates Excision in Long-patch Base Excision Repair

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t).

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Double-strand break repair can lead to high frequencies of deletions within short CAG/CTG trinucleotide repeats

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Relationships between yeast Rad27 and Apn1 in response to apurinic/apyrimidinic (AP) sites in DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2803%2900093-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1568-7864(03)00093-4

1 reference

Europe PubMed Central

2 September 2017

1 reference

Europe PubMed Central

2 September 2017

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