(Q38352205)

2 September 2017

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title

Targeting of tumor-associated gangliosides with antibodies affects signaling pathways and leads to cell death including apoptosis (English)

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2 September 2017

Irena Horwacik

1

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Hanna Rokita

object named as

Hanna Rokita

series ordinal

2

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publication date

1 May 2015

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2 September 2017

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2 September 2017

volume

20

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2 September 2017

issue

5

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2 September 2017

page(s)

679-688

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Structures, biosynthesis, and functions of gangliosides--an overview

2 September 2017

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21 January 2018

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Early stage fetal neocortex exhibits a complex ganglioside profile as revealed by high resolution tandem mass spectrometry

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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GM1 and GM3 gangliosides highlight distinct lipid microdomains within the apical domain of epithelial cells.

21 January 2018

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Ganglioside GM2-tetraspanin CD82 complex inhibits met and its cross-talk with integrins, providing a basis for control of cell motility through glycosynapse

21 January 2018

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Gangliosides in cell recognition and membrane protein regulation

21 January 2018

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Raft component GD3 associates with tubulin following CD95/Fas ligation.

21 January 2018

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Evidence for the involvement of GD3 ganglioside in autophagosome formation and maturation.

21 January 2018

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21 January 2018

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GD3, a prominent ganglioside of human melanoma. Detection and characterisation by mouse monoclonal antibody

21 January 2018

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Disialoganglioside GD2 in human neuroectodermal tumor cell lines and gliomas

21 January 2018

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Selection of GM2, fucosyl GM1, globo H and polysialic acid as targets on small cell lung cancers for antibody mediated immunotherapy

21 January 2018

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The ganglioside antigen G(D2) is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting

21 January 2018

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A monoclonal antibody to O-acetyl-GD2 ganglioside and not to GD2 shows potent anti-tumor activity without peripheral nervous system cross-reactivity

21 January 2018

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21 January 2018

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21 January 2018

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Deacetylated GM3 promotes uPAR-associated membrane molecular complex to activate p38 MAPK in metastatic melanoma

21 January 2018

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Ganglioside inhibition of CD8+ T cell cytotoxicity: interference with lytic granule trafficking and exocytosis

21 January 2018

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Gangliosides drive the tumor infiltration and function of myeloid-derived suppressor cells

21 January 2018

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Tumor gangliosides accelerate murine tumor angiogenesis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The GD2-specific 14G2a monoclonal antibody induces apoptosis and enhances cytotoxicity of chemotherapeutic drugs in IMR-32 human neuroblastoma cells

21 January 2018

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21 January 2018

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Cell cycle arrest and apoptosis induced by O-acetyl-GD2-specific monoclonal antibody 8B6 inhibits tumor growth in vitro and in vivo.

21 January 2018

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Monoclonal anti-GD3 antibodies selectively inhibit the proliferation of human malignant glioma cells in vitro

21 January 2018

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Endothelin A receptor antagonism enhances inhibitory effects of anti-ganglioside GD2 monoclonal antibody on invasiveness and viability of human osteosarcoma cells

21 January 2018

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Characterization of a proapoptotic antiganglioside GM2 monoclonal antibody and evaluation of its therapeutic effect on melanoma and small cell lung carcinoma xenografts.

21 January 2018

1 reference

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Mechanisms for the apoptosis of small cell lung cancer cells induced by anti-GD2 monoclonal antibodies: roles of anoikis

21 January 2018

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GD₃ synthase expression enhances proliferation and tumor growth of MDA-MB-231 breast cancer cells through c-Met activation

21 January 2018

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The ganglioside G(D2) induces the constitutive activation of c-Met in MDA-MB-231 breast cancer cells expressing the G(D3) synthase.

21 January 2018

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A novel HSF1-mediated death pathway that is suppressed by heat shock proteins

21 January 2018

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An anti-GD2 monoclonal antibody enhances apoptotic effects of anti-cancer drugs against small cell lung cancer cells via JNK (c-Jun terminal kinase) activation

21 January 2018

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Mouse monoclonal IgG3 antibody detecting GD3 ganglioside: a phase I trial in patients with malignant melanoma

21 January 2018

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21 January 2018

1 reference

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Phase I study of ch14.18 with granulocyte-macrophage colony-stimulating factor and interleukin-2 in children with neuroblastoma after autologous bone marrow transplantation or stem-cell rescue: a report from the Children's Oncology Group

21 January 2018

1 reference

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Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma

21 January 2018

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Anti-NeuGcGM3 antibodies, actively elicited by idiotypic vaccination in nonsmall cell lung cancer patients, induce tumor cell death by an oncosis-like mechanism

21 January 2018

1 reference

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10.1007/S10495-015-1103-7

21 January 2018

Identifiers

DOI

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release_uzhxt54345fhjkfnldrc5eq434

2 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/uzhxt54345fhjkfnldrc5eq434

mapped directly with Wikidata item

24 November 2022

based on heuristic

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