(Q38352238)

19605626

2 September 2017

title

BMI1 sustains human glioblastoma multiforme stem cell renewal (English)

1 reference

2 September 2017

1 reference

6

Gilbert Bernier

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665439&resulttype=core&format=json

15 May 2020

author name string

Mohamed Abdouh

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665439&resulttype=core&format=json

15 May 2020

Sabrina Facchino

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665439&resulttype=core&format=json

15 May 2020

Wassim Chatoo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665439&resulttype=core&format=json

15 May 2020

Vijayabalan Balasingam

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665439&resulttype=core&format=json

15 May 2020

José Ferreira

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665439&resulttype=core&format=json

15 May 2020

language of work or name

English

0 references

publication date

1 July 2009

1 reference

19605626

2 September 2017

number of pages

13

1 reference

inferred from page(s)

published in

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665439&resulttype=core&format=json

15 May 2020

volume

29

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665439&resulttype=core&format=json

15 May 2020

issue

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665439&resulttype=core&format=json

15 May 2020

page(s)

8884-8896

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665439&resulttype=core&format=json

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

15 May 2020

cites work

1 reference

12 December 2020

Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development

1 reference

12 December 2020

Gliomagenesis: genetic alterations and mouse models

1 reference

12 December 2020

BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas

1 reference

12 December 2020

The Polycomb group protein EZH2 is upregulated in proliferating, cultured human mantle cell lymphoma

1 reference

12 December 2020

The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression

1 reference

12 December 2020

Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma.

1 reference

12 December 2020

Malignant glioma: genetics and biology of a grave matter.

1 reference

12 December 2020

The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans

1 reference

12 December 2020

The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells

1 reference

12 December 2020

The polycomb group protein EZH2 is involved in progression of prostate cancer

1 reference

12 December 2020

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

1 reference

12 December 2020

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

1 reference

12 December 2020

Neural progenitor cells lack immunogenicity and resist destruction as allografts.

1 reference

12 December 2020

Overexpression of multiple oncogenes related to histological grade of astrocytic glioma

1 reference

12 December 2020

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

1 reference

12 December 2020

Identification of a cancer stem cell in human brain tumors

1 reference

12 December 2020

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

1 reference

12 December 2020

Cancerous stem cells can arise from pediatric brain tumors

1 reference

12 December 2020

Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas

1 reference

12 December 2020

Polycomb silencing blocks transcription initiation.

1 reference

12 December 2020

Hierarchical recruitment of polycomb group silencing complexes

1 reference

12 December 2020

Stem cells and cancer; the polycomb connection

1 reference

12 December 2020

Overexpression of Bmi-1 oncoprotein correlates with axillary lymph node metastases in invasive ductal breast cancer

1 reference

12 December 2020

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

1 reference

12 December 2020

Absence of major histocompatibility complex class I on neural stem cells does not permit natural killer cell killing and prevents recognition by alloreactive cytotoxic T lymphocytes in vitro

1 reference

12 December 2020

Identification of human brain tumour initiating cells

1 reference

12 December 2020

Isolation of cancer stem cells from adult glioblastoma multiforme

1 reference

12 December 2020

Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain

1 reference

12 December 2020

Bmi1 loss produces an increase in astroglial cells and a decrease in neural stem cell population and proliferation.

1 reference

12 December 2020

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways

1 reference

12 December 2020

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice

1 reference

12 December 2020

FOXO transcription factors at the interface between longevity and tumor suppression

1 reference

12 December 2020

Human leukocyte antigen and antigen processing machinery component defects in astrocytic tumors.

1 reference

12 December 2020

Control of developmental regulators by Polycomb in human embryonic stem cells

1 reference

12 December 2020

Dissecting self-renewal in stem cells with RNA interference

1 reference

12 December 2020

Overexpression of c-MYC promotes an undifferentiated phenotype in cultured astrocytes and allows elevated Ras and Akt signaling to induce gliomas from GFAP-expressing cells in mice

1 reference

12 December 2020

Polycomb silencers control cell fate, development and cancer

1 reference

12 December 2020

A perivascular niche for brain tumor stem cells

1 reference

12 December 2020

Cell survival, cell death and cell cycle pathways are interconnected: implications for cancer therapy

1 reference

12 December 2020

Genetic pathways to primary and secondary glioblastoma

1 reference

12 December 2020

Expression of p16Ink4a compensates for p18Ink4c loss in cyclin-dependent kinase 4/6-dependent tumors and tissues.

1 reference

12 December 2020

The 2007 WHO classification of tumours of the central nervous system

1 reference

12 December 2020

INK4 proteins, a family of mammalian CDK inhibitors with novel biological functions.

1 reference

12 December 2020

Allorecognition of human neural stem cells by peripheral blood lymphocytes despite low expression of MHC molecules: role of TGF-beta in modulating proliferation.

1 reference

12 December 2020

Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma

1 reference

12 December 2020

FoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis

1 reference

12 December 2020

BMI1 as oncogenic candidate in a novel TCRB-associated chromosomal aberration in a patient with TCRgammadelta+ T-cell acute lymphoblastic leukemia

1 reference

12 December 2020

shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development

1 reference

12 December 2020

Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development

1 reference

12 December 2020

FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression.

1 reference

12 December 2020

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

1 reference

12 December 2020

p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

1 reference

12 December 2020

Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging

1 reference

12 December 2020

Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice.

1 reference

12 December 2020

The polycomb group gene Bmi1 regulates antioxidant defenses in neurons by repressing p53 pro-oxidant activity

1 reference

12 December 2020

Enhanced radiosensitivity and radiation-induced apoptosis in glioma CD133-positive cells by knockdown of SirT1 expression

1 reference

12 December 2020

Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice

1 reference

12 December 2020

Monoclonal antibodies specific for endothelial cells of mouse blood vessels. Their application in the identification of adult and embryonic endothelium

1 reference

12 December 2020

Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression

1 reference

12 December 2020

Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice

1 reference

12 December 2020

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

1 reference

12 December 2020

10.1523/JNEUROSCI.0968-09.2009

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665439&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665439&resulttype=core&format=json

15 May 2020

19605626

1 reference