(Q38354788)

English

Mechanistic Understanding of an Altered Fidelity Simian Immunodeficiency Virus Reverse Transcriptase Mutation, V148I, Identified in a Pig-tailed Macaque

scientific article published on May 8, 2003

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scholarly article

1 reference

Europe PubMed Central

2 September 2017

Mechanistic understanding of an altered fidelity simian immunodeficiency virus reverse transcriptase mutation, V148I, identified in a pig-tailed macaque (English)

1 reference

Europe PubMed Central

2 September 2017

Mechanistic Understanding of an Altered Fidelity Simian Immunodeficiency Virus Reverse Transcriptase Mutation, V148I, Identified in a Pig-tailed Macaque (English)

1 reference

10.1074/JBC.M211754200

https://api.crossref.org/works/10.1074/JBC.M211754200

1 January 2024

Simian immunodeficiency virus

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1 reference

10.1074/JBC.M211754200

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1 January 2024

1 reference

10.1074/JBC.M211754200

https://api.crossref.org/works/10.1074/JBC.M211754200

1 January 2024

Stephen Dewhurst

6

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Stephen Dewhurst

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1 January 2024

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George Souroullas

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2 September 2017

Baek Kim

7

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Tracy L. Diamond

1

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Kellie K. Weiss

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1 January 2024

Kwi Y. Lee

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1 January 2024

Robert A. Bambara

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publication date

8 May 2003

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2 September 2017

full work available at URL

http://www.jbc.org/article/S0021925820842598/pdf

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online access status

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https://api.elsevier.com/content/article/PII:S0021925820842598?httpAccept=text/xml

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10.1074/JBC.M211754200

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1 January 2024

https://api.elsevier.com/content/article/PII:S0021925820842598?httpAccept=text/plain

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10.1074/JBC.M211754200

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1 January 2024

https://syndication.highwire.org/content/doi/10.1074/jbc.M211754200

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10.1074/JBC.M211754200

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Journal of Biological Chemistry

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2 September 2017

278

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2 September 2017

32

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2 September 2017

29913-29924

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Europe PubMed Central

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HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

1 reference

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Transition between stochastic evolution and deterministic evolution in the presence of selection: general theory and application to virology.

1 reference

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Mutational analysis of HIV-1 long terminal repeats to explore the relative contribution of reverse transcriptase and RNA polymerase II to viral mutagenesis

1 reference

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Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro

1 reference

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21 January 2018

Conformational coupling in DNA polymerase fidelity

1 reference

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Kinetic mechanism of DNA polymerase I (Klenow).

1 reference

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21 January 2018

A mutant of DNA polymerase I (Klenow fragment) with reduced fidelity

1 reference

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Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

1 reference

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Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation

1 reference

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Low fidelity mutants in the O-helix of Thermus aquaticus DNA polymerase I.

1 reference

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Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase

1 reference

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21 January 2018

Mispair extension fidelity of human immunodeficiency virus type 1 reverse transcriptases with amino acid substitutions affecting Tyr115.

1 reference

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21 January 2018

Coupling ribose selection to fidelity of DNA synthesis. The role of Tyr-115 of human immunodeficiency virus type 1 reverse transcriptase.

1 reference

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21 January 2018

Mechanistic role of residue Gln151 in error prone DNA synthesis by human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). Pre-steady state kinetic study of the Q151N HIV-1 RT mutant with increased fidelity

1 reference

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21 January 2018

The influence of 3TC resistance mutation M184I on the fidelity and error specificity of human immunodeficiency virus type 1 reverse transcriptase

1 reference

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Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase

1 reference

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Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids

1 reference

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Progression to AIDS in macaques is associated with changes in the replication, tropism, and cytopathic properties of the simian immunodeficiency virus variant population.

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Identification of a simian immunodeficiency virus reverse transcriptase variant with enhanced replicational fidelity in the late stage of viral infection.

1 reference

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Genetic selection in Escherichia coli for active human immunodeficiency virus reverse transcriptase mutants

1 reference

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Analyzing fidelity of DNA polymerases.

1 reference

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Rapid quench kinetic analysis of polymerases, adenosinetriphosphatases, and enzyme intermediates

1 reference

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Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S. Template interactions influence substrate recognition at the polymerase active site

1 reference

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21 January 2018

Analysis of nucleotide insertion and extension at 8-oxo-7,8-dihydroguanine by replicative T7 polymerase exo- and human immunodeficiency virus-1 reverse transcriptase using steady-state and pre-steady-state kinetics

1 reference

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21 January 2018

An induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kinetics

1 reference

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21 January 2018

Role of glutamine 151 of human immunodeficiency virus type-1 reverse transcriptase in substrate selection as assessed by site-directed mutagenesis

1 reference

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21 January 2018

Molecular architecture of the mutagenic active site of human immunodeficiency virus type 1 reverse transcriptase: roles of the beta 8-alpha E loop in fidelity, processivity, and substrate interactions

1 reference

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21 January 2018

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

1 reference

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21 January 2018

Physiological concentrations of purines and pyrimidines

1 reference

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21 January 2018

Thermus aquaticus DNA polymerase I mutants with altered fidelity. Interacting mutations in the O-helix

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M211754200

1 reference

Europe PubMed Central

2 September 2017

1 reference

Europe PubMed Central

2 September 2017

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