(Q38357335)

2 September 2017

The gep oncogenes, Galpha(12) and Galpha(13), upregulate the transforming growth factor-beta1 gene (English)

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2 September 2017

S J Lee

1

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2 September 2017

J W Yang

2

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2 September 2017

I J Cho

3

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2 September 2017

W D Kim

4

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2 September 2017

M K Cho

5

1 reference

2 September 2017

C H Lee

6

1 reference

2 September 2017

S G Kim

7

1 reference

2 September 2017

language of work or name

English

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publication date

19 January 2009

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2 September 2017

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2 September 2017

28

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2 September 2017

9

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2 September 2017

1230-1240

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https://scigraph.springernature.com/pub.10.1038/onc.2008.488

2 September 2017

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1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Galpha12 specifically regulates COX-2 induction by sphingosine 1-phosphate. Role for JNK-dependent ubiquitination and degradation of IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Control of the tissue inhibitor of metalloproteinases-1 promoter in culture-activated rat hepatic stellate cells: regulation by activator protein-1 DNA binding proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Angiotensin II induces contraction and proliferation of human hepatic stellate cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

The Rac and Rho hall of fame: a decade of hypertrophic signaling hits

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

A splice variant of CD99 increases motility and MMP-9 expression of human breast cancer cells through the AKT-, ERK-, and JNK-dependent AP-1 activation signaling pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Signaling by the G12 class of G proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

PAR1 antagonism protects against experimental liver fibrosis. Role of proteinase receptors in stellate cell activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Regulation of hepatic stellate cell proliferation and collagen synthesis by proteinase-activated receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Molecular characteristics of dimethylnitrosamine induced fibrotic liver collagen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Dimethylnitrosamine-induced liver injury in rats: the early deposition of collagen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Laminin-5 with transforming growth factor-beta1 induces epithelial to mesenchymal transition in hepatocellular carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

G protein regulation of MAPK networks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Cyclooxygenase-derived products modulate the increased intrahepatic resistance of cirrhotic rat livers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

A dimethylnitrosamine-induced model of cirrhosis and portal hypertension in the rat.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Inhibition of dimethylnitrosamine-induced liver fibrosis by [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] (oltipraz) in rats: suppression of transforming growth factor-beta1 and tumor necrosis factor-alpha expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Thrombin induces nitric-oxide synthase via Galpha12/13-coupled protein kinase C-dependent I-kappaBalpha phosphorylation and JNK-mediated I-kappaBalpha degradation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Oltipraz regenerates cirrhotic liver through CCAAT/enhancer binding protein-mediated stellate cell inactivation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Thrombin-mediated hepatocellular carcinoma cell migration: cooperative action via proteinase-activated receptors 1 and 4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Molecular mechanism for endothelin-1-induced stress-fiber formation: analysis of G proteins using a mutant endothelin(A) receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Biologic functions of the G12 subfamily of heterotrimeric g proteins: growth, migration, and metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Neoplastic transformation by the gep oncogene, Galpha12, involves signaling by STAT3.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Characterization of the expression of PDZ-RhoGEF, LARG and G(alpha)12/G(alpha)13 proteins in the murine nervous system.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Gα12 and Gα13 as key regulatory mediator in signal transduction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Sinusoidal remodeling and angiogenesis: a new function for the liver-specific pericyte?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Activated hepatic stellate cells induce tumor progression of neoplastic hepatocytes in a TGF-beta dependent fashion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Potential deployment of angiotensin I converting enzyme inhibitors and of angiotensin II type 1 and type 2 receptor blockers in cancer chemotherapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

The latent transforming growth factor beta binding protein (LTBP) family

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Tumor-dependent activation of rodent hepatic stellate cells during experimental melanoma metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Mitogenic signaling by lysophosphatidic acid (LPA) involves Galpha12.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Dimethylnitrosamine (DMN)-induced IL-1 beta, TNF-alpha, and IL-6 inflammatory cytokine expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

JunD is a profibrogenic transcription factor regulated by Jun N-terminal kinase-independent phosphorylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

G proteins are involved in the suppression of collagen alpha 1 (I) gene expression in cultured rat hepatic stellate cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Prolonged photoresponses in transgenic mouse rods lacking arrestin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Potent transforming activity of the G13 alpha subunit defines a novel family of oncogenes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

N-terminal short sequences of alpha subunits of the G12 family determine selective coupling to receptors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Renin-angiotensin system inhibitors as therapeutic alternatives in the treatment of chronic liver diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Requirement of Ras/MAPK pathway activation by transforming growth factor beta for transforming growth factor beta 1 production in a Smad-dependent pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.488

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.488

1 reference

Dimensions Publication ID

2 September 2017

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1 reference