(Q36819372)

16 August 2017

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title

G protein regulation of MAPK networks (English)

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16 August 2017

Goldsmith ZG

1

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16 August 2017

Dhanasekaran DN

series ordinal

2

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16 August 2017

language of work or name

English

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publication date

1 May 2007

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16 August 2017

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16 August 2017

26

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16 August 2017

22

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16 August 2017

3122-3142

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210407

16 August 2017

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cites work

Rap1 and p38 MAPK mediate 8-chloro-cAMP-induced growth inhibition in mouse fibroblast DT cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

8-Chloro-cyclic AMP-induced growth inhibition and apoptosis is mediated by p38 mitogen-activated protein kinase activation in HL60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Constitutively active Galphaq and Galpha13 trigger apoptosis through different pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

The guanine nucleotide exchange factor CNrasGEF regulates melanogenesis and cell survival in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

G12 requirement for thrombin-stimulated gene expression and DNA synthesis in 1321N1 astrocytoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Regulation of Apoptosis by α-Subunits of G12 and G13 Proteins via Apoptosis Signal-regulating Kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

G protein-coupled receptor-mediated mitogen-activated protein kinase activation through cooperation of Galpha(q) and Galpha(i) signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Adaptor proteins Grb2 and Crk couple Pyk2 with activation of specific mitogen-activated protein kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Epac proteins: multi-purpose cAMP targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Mammalian MAP kinase signalling cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Galpha13 mediates a signal that is essential for proliferation and survival of thymocyte progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Galpha12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

The G12 coupled thrombin receptor stimulates mitogenesis through the Shc SH2 domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Structural elements of G alpha subunits that interact with G beta gamma, receptors, and effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Platelet-derived-growth-factor stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle: role of pertussis-toxin-sensitive G-proteins, c-Src tyrosine kinases and phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Inhibition by cAMP of Ras-dependent activation of Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Signaling from G protein-coupled receptors to c-Jun kinase involves beta gamma subunits of heterotrimeric G proteins acting on a Ras and Rac1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Signal characteristics of G protein-transactivated EGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Signal transduction by the JNK group of MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Involvement of Ras in Bruton's tyrosine kinase-mediated JNK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Mutant alpha-subunit of the G protein G12 activates proliferation and inhibits differentiation of 3T3-F442A preadipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Differential regulation of Jun N-terminal kinase and p38MAP kinase by Galpha12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Signaling by the G12 class of G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

G protein-coupled receptor systems involved in cell growth and oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

G protein subunits and cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Signaling by dual specificity kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Integrating signals between cAMP and the RAS/RAF/MEK/ERK signalling pathways. Based on the anniversary prize of the Gesellschaft für Biochemie und Molekularbiologie Lecture delivered on 5 July 2003 at the Special FEBS Meeting in Brussels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Expression of an oncogenic mutant G alpha i2 activates Ras in Rat-1 fibroblast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Signaling from G protein-coupled receptors to ERK5/Big MAPK 1 involves Galpha q and Galpha 12/13 families of heterotrimeric G proteins. Evidence for the existence of a novel Ras AND Rho-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Organization and regulation of mitogen-activated protein kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Extracellular ATP is an autocrine/paracrine regulator of hypoxia-induced adventitial fibroblast growth. Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

ATF-1 mediates protease-activated receptor-1 but not receptor tyrosine kinase-induced DNA synthesis in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

A direct interaction between JNK1 and CrkII is critical for Rac1-induced JNK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Protein kinase C phosphorylates pp60src at a novel site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

MRK, a mixed lineage kinase-related molecule that plays a role in gamma-radiation-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Analysis of the fibroblast transformation potential of GTPase-deficient gip2 oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Mechanism of inhibition of Raf-1 by protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Effect of cellular expression of pleckstrin homology domains on Gi-coupled receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

MAP kinase pathways in yeast: for mating and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

A RSK(y) relationship with promiscuous PKA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Rap1-induced p38 mitogen-activated protein kinase activation facilitates AMPA receptor trafficking via the GDI.Rab5 complex. Potential role in (S)-3,5-dihydroxyphenylglycene-induced long term depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Cell signalling diversity of the Gqalpha family of heterotrimeric G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

The transforming activity of activated G alpha 12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

The G protein G alpha12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Phosphatidylinositol-3 kinase is distinctively required for mu-, but not kappa-opioid receptor-induced activation of c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

JNK-interacting leucine zipper protein is a novel scaffolding protein in the Galpha13 signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Endodermal differentiation of murine embryonic carcinoma cells by retinoic acid requires JLP, a JNK-scaffolding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Selective Involvement of p130Cas/Crk/Pyk2/c-Src in Endothelin-1-Induced JNK Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Protein kinase C alpha activates RAF-1 by direct phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Ras-MAP kinase signaling by lysophosphatidic acid and other G protein-coupled receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Gi-mediated tyrosine phosphorylation of Grb2 (growth-factor-receptor-bound protein 2)-bound dynamin-II by lysophosphatidic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Gi-mediated activation of the Ras/MAP kinase pathway involves a 100 kDa tyrosine-phosphorylated Grb2 SH3 binding protein, but not Src nor Shc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Transactivation of platelet-derived growth factor receptor alpha by the GTPase-deficient activated mutant of Galpha12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Protein kinase A-independent activation of ERK and H,K-ATPase by cAMP in native kidney cells: role of Epac I

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

G alpha 13 signals via p115RhoGEF cascades regulating JNK1 and primitive endoderm formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Transduction of receptor signals by beta-arrestins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Activation of JNK3 alpha 1 requires both MKK4 and MKK7: kinetic characterization of in vitro phosphorylated JNK3 alpha 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

The constitutively active mutant Galpha13 transforms mouse fibroblast cells deficient in insulin-like growth factor-I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Two G protein oncogenes in human endocrine tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: a role for c-Jun NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Thrombin protease-activated receptor-1 signals through Gq- and G13-initiated MAPK cascades regulating c-Jun expression to induce cell transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

The emerging role of lysophosphatidic acid in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Regulation and function of the JNK subgroup of MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Negative regulation of Raf-1 by phosphorylation of serine 621.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Differential calcium dependence in the activation of c-Jun kinase and mitogen-activated protein kinase by muscarinic acetylcholine receptors in rat 1a cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Dependence of activated Galpha12-induced G1 to S phase cell cycle progression on both Ras/mitogen-activated protein kinase and Ras/Rac1/Jun N-terminal kinase cascades in NIH3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Crk activation of JNK via C3G and R-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

The sites of phosphorylation by protein kinase C and an intact SH2 domain are required for the enhanced response to beta-adrenergic agonists in cells overexpressing c-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Angiotensin II type 1 receptor-induced extracellular signal-regulated protein kinase activation is mediated by Ca2+/calmodulin-dependent transactivation of epidermal growth factor receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

The Src family tyrosine kinase is involved in Rho-dependent activation of c-Jun N-terminal kinase by Galpha12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Epac- and Rap- independent ERK1/2 phosphorylation induced by Gs-coupled receptor stimulation in HEK293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Ras-dependent ERK activation by the human G(s)-coupled serotonin receptors 5-HT4(b) and 5-HT7(a).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Gi2-mediated activation of the MAP kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

A mutant alpha subunit of Gi2 induces neoplastic transformation of Rat-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Cyclic AMP selectively uncouples mitogen-activated protein kinase cascades from activating signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Transmembrane Receptors and Intracellular Pathways that Control Cell Proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

The dynamin superfamily: universal membrane tubulation and fission molecules?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Activation of Jun kinase/stress-activated protein kinase by GTPase-deficient mutants of G alpha 12 and G alpha 13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

21 January 2018

Transforming G proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Galpha13 stimulates cell migration through cortactin-interacting protein Hax-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

The MEKK-JNK pathway is stimulated by alpha1-adrenergic receptor and ras activation and is associated with in vitro and in vivo cardiac hypertrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

beta 2-adrenergic receptor activates extracellular signal-regulated kinases (ERKs) via the small G protein rap1 and the serine/threonine kinase B-Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Activated G protein-coupled receptor induces tyrosine phosphorylation of STAT3 and agonist-selective serine phosphorylation via sustained stimulation of mitogen-activated protein kinase. Resultant effects on cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

The G protein G alpha(13) is required for growth factor-induced cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Diversity of G proteins in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Regulation of a mitogen-activated protein kinase kinase kinase, MLTK by PKN

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Guanine-nucleotide exchange protein C3G activates JNK1 by a ras-independent mechanism. JNK1 activation inhibited by kinase negative forms of MLK3 and DLK mixed lineage kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Activation of Pyk2 by stress signals and coupling with JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Cyclic AMP activates Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Galpha12 differentially regulates Na+-H+ exchanger isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Analysis of the Gs/mitogen-activated protein kinase pathway in mutant S49 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Expression of Galpha 13 (Q226L) induces P19 stem cells to primitive endoderm via MEKK1, 2, or 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Brain-derived neurotrophic factor activates ERK5 in cortical neurons via a Rap1-MEKK2 signaling cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

c-Src is involved in regulating signal transmission from PDGFbeta receptor-GPCR(s) complexes in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

"Ins and outs" of seven-transmembrane receptor signalling to ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Mutant α subunits of Gi2 inhibit cyclic AMP accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3',5'-monophosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Characterization of interactions of Nck with Sos and dynamin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Potent transforming activity of the G13 alpha subunit defines a novel family of oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Involvement of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase in alpha1B-adrenergic receptor/Galphaq-induced inhibition of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Differential regulation of mitogen-activated protein kinase kinase 4 (MKK4) and 7 (MKK7) by signaling from G protein beta gamma subunit in human embryonal kidney 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Activation of p38 mitogen-activated protein kinase by signaling through G protein-coupled receptors. Involvement of Gbetagamma and Galphaq/11 subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Extracellular signal-regulated kinase 1/2 activation by myometrial oxytocin receptor involves Galpha(q)Gbetagamma and epidermal growth factor receptor tyrosine kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Galpha12 directly interacts with PP2A: evidence FOR Galpha12-stimulated PP2A phosphatase activity and dephosphorylation of microtubule-associated protein, tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

cAMP cascade leads to Ras activation in cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Differential requirement of G alpha12, G alpha13, G alphaq, and G beta gamma for endothelin-1-induced c-Jun NH2-terminal kinase and extracellular signal-regulated kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Endothelin-1 activates c-Jun NH2-terminal kinase in mesangial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Dual effect of beta-adrenergic receptors on mitogen-activated protein kinase. Evidence for a beta gamma-dependent activation and a G alpha s-cAMP-mediated inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Signal transduction. Signaling specificity in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

G proteins: transducers of receptor-generated signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Adenylyl cyclase isoform-selective regulation of vascular smooth muscle proliferation and cytoskeletal reorganization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Cell growth control by G protein-coupled receptors: from signal transduction to signal integration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Endothelin-mediated vascular growth requires p42/p44 mitogen-activated protein kinase and p70 S6 kinase cascades via transactivation of epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

c-Jun amino-terminal kinase is regulated by Galpha12/Galpha13 and obligate for differentiation of P19 embryonal carcinoma cells by retinoic acid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Galpha12 and Galpha13 mediate differentiation of P19 mouse embryonal carcinoma cells in response to retinoic acid

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

The G-protein family and their interaction with receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Thrombin induces activation of p38 MAP kinase in human platelets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Chemotactic peptide N-formyl-met-leu-phe activation of p38 mitogen-activated protein kinase (MAPK) and MAPK-activated protein kinase-2 in human neutrophils

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

p42/mitogen-activated protein kinase as a converging target for different growth factor signaling pathways: use of pertussis toxin as a discrimination factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Involvement of protein kinase C and Src family tyrosine kinase in Galphaq/11-induced activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

G protein-controlled signal transduction pathways and the regulation of cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

The seven-transmembrane-spanning receptors for endothelin and thrombin cause proliferation of airway smooth muscle cells and activation of the extracellular regulated kinase and c-Jun NH2-terminal kinase groups of mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Differential regulation of NF-kappaB, SRE and CRE by dopamine D1 and D2 receptors in transfected NG108-15 cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Galpha12 and Galpha13 regulate extracellular signal-regulated kinase and c-Jun kinase pathways by different mechanisms in COS-7 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

G(i)-dependent activation of c-Jun N-terminal kinase in human embryonal kidney 293 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

beta 2-adrenergic receptor-induced p38 MAPK activation is mediated by protein kinase A rather than by Gi or gbeta gamma in adult mouse cardiomyocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Critical role of calcium- dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210407

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210407

1 reference

Dimensions Publication ID

16 August 2017

0 references

1 reference