(Q41175767)

English

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

scientific article published on August 1996

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scholarly article

1 reference

Europe PubMed Central

27 September 2017

Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases (English)

1 reference

Europe PubMed Central

27 September 2017

G protein-coupled receptor

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Robert Lefkowitz

6

object named as

Lefkowitz RJ

1 reference

Europe PubMed Central

27 September 2017

author name string

Luttrell LM

1

1 reference

Europe PubMed Central

27 September 2017

Hawes BE

2

1 reference

Europe PubMed Central

27 September 2017

van Biesen T

3

1 reference

Europe PubMed Central

27 September 2017

Luttrell DK

4

1 reference

Europe PubMed Central

27 September 2017

Lansing TJ

5

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Europe PubMed Central

27 September 2017

language of work or name

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publication date

1 August 1996

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Europe PubMed Central

27 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

27 September 2017

271

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Europe PubMed Central

27 September 2017

19443-19450

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Europe PubMed Central

27 September 2017

32

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Europe PubMed Central

27 September 2017

Lysophosphatidic acid, a multifunctional phospholipid messenger

1 reference

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21 January 2018

Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins.

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Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts

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Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway

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G protein beta gamma subunit activates Ras, Raf, and MAP kinase in HEK 293 cells

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G protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase.Shc adapter protein signaling complexes

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21 January 2018

G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein

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Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase

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21 January 2018

cDNA-derived amino acid sequence of the gamma subunit of GTPase from bovine rod outer segments

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Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src

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Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain

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Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

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Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

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A mutation at the ATP-binding site of pp60v-src abolishes kinase activity, transformation, and tumorigenicity

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Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

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Functional expression and growth factor activation of an epitope-tagged p44 mitogen-activated protein kinase, p44mapk

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Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

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Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases

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A dominant-negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and -independent insulin signaling pathways

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Constitutive activation of Src family kinases in mouse embryos that lack Csk.

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21 January 2018

Csk suppression of Src involves movement of Csk to sites of Src activity

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21 January 2018

Overexpression of csk inhibits acid-induced activation of NHE-3.

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Shc isoform-specific tyrosine phosphorylation by the insulin and epidermal growth factor receptors

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Involvement of pp60c-src with two major signaling pathways in human breast cancer

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Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha

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Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

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A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

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21 January 2018

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

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Association of type I phosphatidylinositol kinase activity with mutationally activated forms of human pp60c-src

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Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction

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21 January 2018

Src family protein tyrosine kinases induce autoactivation of Bruton's tyrosine kinase

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21 January 2018

Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors

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21 January 2018

Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits

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21 January 2018

Angiotensin II Activates pp60 c- src in Vascular Smooth Muscle Cells

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Thrombin Stimulates Phosphorylation of Insulin-like Growth Factor-1 Receptor, Insulin Receptor Substrate-1, and Phospholipase C-γ1 in Rat Aortic Smooth Muscle Cells

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Malignant transformation of early passage rodent cells by a single mutated human oncogene

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Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses

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Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid

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Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells

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Integrins and signal transduction pathways: the road taken

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Isolation and structural mapping of a human c-src gene homologous to the transforming gene (v-src) of Rous sarcoma virus

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Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation

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Identifiers

10.1074/JBC.271.32.19443

1 reference

Europe PubMed Central

27 September 2017

1 reference

Europe PubMed Central

27 September 2017

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