(Q34020904)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq (English)

1 reference

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8 December 2019

7

1 reference

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8 December 2019

author name string

Tetsuo Minamino

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Toshiaki Yujiri

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Naohiro Terada

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

George E Taffet

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Lloyd H Michael

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Gary L Johnson

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

language of work or name

English

0 references

publication date

12 March 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

8 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

volume

99

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

page(s)

3866-3871

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

8 December 2019

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC122615/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival

1 reference

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Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

5 July 2018

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Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo

5 July 2018

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Mammalian MAP kinase signalling cascades

5 July 2018

1 reference

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Cytoplasmic signaling pathways that regulate cardiac hypertrophy

5 July 2018

1 reference

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The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

5 July 2018

1 reference

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Decoding calcium signals involved in cardiac growth and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells

5 July 2018

1 reference

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Dominant-negative activity of an alpha(1B)-adrenergic receptor signal-inactivating point mutation

5 July 2018

1 reference

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Angiotensin II initiates tyrosine kinase Pyk2-dependent signalings leading to activation of Rac1-mediated c-Jun NH2-terminal kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

Genetic dissection of cardiac growth control pathways

5 July 2018

1 reference

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Small guanine nucleotide-binding proteins and myocardial hypertrophy

5 July 2018

1 reference

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Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial--the Losartan Heart Failure Survival Study ELITE II.

5 July 2018

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Specific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitro

5 July 2018

1 reference

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Protection of nonobese diabetic mice from diabetes by gene(s) closely linked to IFN-gamma receptor loci.

5 July 2018

1 reference

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Mekk3 is essential for early embryonic cardiovascular development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

Stress pathways and heart failure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

Regulation of cardiac hypertrophy in vivo by the stress-activated protein kinases/c-Jun NH(2)-terminal kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

Gq signaling in cardiac adaptation and maladaptation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

Stem cell factor augments Fc epsilon RI-mediated TNF-alpha production and stimulates MAP kinases via a different pathway in MC/9 mast cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122615

Transgenic Galphaq overexpression induces cardiac contractile failure in mice

5 July 2018

1 reference

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MAP kinase- and Rho-dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells

5 July 2018

1 reference

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NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

5 July 2018

1 reference

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Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion

5 July 2018

1 reference

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A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

5 July 2018

1 reference

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Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

5 July 2018

1 reference

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FVB/N: an inbred mouse strain preferable for transgenic analyses

5 July 2018

1 reference

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MEK kinase 1 (MEKK1) transduces c-Jun NH2-terminal kinase activation in response to changes in the microtubule cytoskeleton.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.062453699

Regulation of Apoptosis by α-Subunits of G12 and G13 Proteins via Apoptosis Signal-regulating Kinase-1

21 January 2018

1 reference

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Inducible gene targeting in postnatal myocardium by cardiac-specific expression of a hormone-activated Cre fusion protein.

21 January 2018

1 reference

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Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.062453699

Inhibition of myocardial endothelin pathway improves long-term survival in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.062453699

TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11891332

12 December 2020

inferred from PubMed ID database lookup

RGS4 reduces contractile dysfunction and hypertrophic gene induction in Galpha q overexpressing mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11891332

12 December 2020

inferred from PubMed ID database lookup

Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11891332

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.062453699

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891332%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

PubMed publication ID

11891332

1 reference