(Q29040265)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12102558%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

review article

1 reference

title

A growing family of guanine nucleotide exchange factors is responsible for activation of Ras-family GTPases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12102558%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12102558%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

Lawrence A Quilliam

series ordinal

1

2 references

https://doi.org/10.1016%2FS0079-6603%2802%2971047-7

27 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12102558%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Ariel F Castro

series ordinal

3

2 references

https://doi.org/10.1016%2FS0079-6603%2802%2971047-7

27 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12102558%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

publication date

1 January 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12102558%20AND%20SRC:MED&resulttype=core&format=json

Progress in Molecular Biology and Translational Science

10 November 2019

published in

2 references

https://doi.org/10.1016%2FS0079-6603%2802%2971047-7

27 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12102558%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

71

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12102558%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

page(s)

391-444

2 references

https://doi.org/10.1016%2FS0079-6603%2802%2971047-7

27 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12102558%20AND%20SRC:MED&resulttype=core&format=json

The ras protein family: evolutionary tree and role of conserved amino acids

10 November 2019

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Rho GTPases and the actin cytoskeleton

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Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

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7 January 2021

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7 January 2021

Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle?

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7 January 2021

Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins

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7 January 2021

Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3

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7 January 2021

Proteins regulating Ras and its relatives

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7 January 2021

Rap1 signalling: adhering to new models

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7 January 2021

Ral GTPases contribute to regulation of cyclin D1 through activation of NF-kappaB.

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7 January 2021

The Ras branch of small GTPases: Ras family members don't fall far from the tree

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7 January 2021

RERG is a novel ras-related, estrogen-regulated and growth-inhibitory gene in breast cancer

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7 January 2021

Rem2, a new member of the Rem/Rad/Gem/Kir family of Ras-related GTPases

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7 January 2021

A subclass of Ras proteins that regulate the degradation of IkappaB

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7 January 2021

Chemotactic peptide-induced activation of Ras in human neutrophils is associated with inhibition of p120-GAP activity

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7 January 2021

A permissive function of phosphoinositide 3-kinase in Ras activation mediated by inhibition of GTPase-activating proteins

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7 January 2021

Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)

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7 January 2021

Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein.

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7 January 2021

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

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7 January 2021

CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The CDC25 protein of Saccharomyces cerevisiae promotes exchange of guanine nucleotides bound to ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

SmgGDS stabilizes nucleotide-bound and -free forms of the Rac1 GTP-binding protein and stimulates GTP/GDP exchange through a substituted enzyme mechanism

1 reference

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7 January 2021

Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein

1 reference

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7 January 2021

The Son of sevenless Gene Product: a Putative Activator of Ras

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7 January 2021

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

1 reference

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7 January 2021

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The Dbl family of oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral

1 reference

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7 January 2021

The structural basis of the activation of Ras by Sos

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7 January 2021

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

1 reference

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7 January 2021

Structure-based mutagenesis reveals distinct functions for Ras switch 1 and switch 2 in Sos-catalyzed guanine nucleotide exchange

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7 January 2021

GEF-mediated GDP/GTP exchange by monomeric GTPases: a regulatory role for Mg2+?

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7 January 2021

Kinetic analysis by fluorescence of the interaction between Ras and the catalytic domain of the guanine nucleotide exchange factor Cdc25Mm

1 reference

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7 January 2021

Distinct subclasses of small GTPases interact with guanine nucleotide exchange factors in a similar manner

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7 January 2021

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

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7 January 2021

Structural Basis for Activation of ARF GTPase

1 reference

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7 January 2021

Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

1 reference

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7 January 2021

Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction

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7 January 2021

Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

1 reference

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7 January 2021

Two types of RAS mutants that dominantly interfere with activators of RAS.

1 reference

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7 January 2021

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

1 reference

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7 January 2021

The GTPase Rap1 controls functional activation of macrophage integrin alphaMbeta2 by LPS and other inflammatory mediators

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Dominant inhibitory Ras mutants selectively inhibit the activity of either cellular or oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Two distinct Raf domains mediate interaction with Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Determination of guanine nucleotides bound to Ras in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Cell cycle-dependent activation of Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Measurement of GTP-bound Ras-like GTPases by activation-specific probes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Nonradioactive determination of Ras-GTP levels using activated ras interaction assay

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Structure determination of the Ras-binding domain of the Ral-specific guanine nucleotide exchange factor Rlf

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Point mutants of c-raf-1 RBD with elevated binding to v-Ha-Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

c-Raf-1 RBD associates with a subset of active v-H-Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Localized Rac activation dynamics visualized in living cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Spatio-temporal images of growth-factor-induced activation of Ras and Rap1.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties

1 reference

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7 January 2021

Ras-guanine nucleotide exchange factor sos2 is dispensable for mouse growth and development

1 reference

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7 January 2021

The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The pathway to signal achievement

1 reference

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7 January 2021

Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2

1 reference

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7 January 2021

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

1 reference

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7 January 2021

How receptor tyrosine kinases activate Ras.

1 reference

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7 January 2021

Signal transduction from the extracellular matrix--a role for the focal adhesion protein-tyrosine kinase FAK.

1 reference

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7 January 2021

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The Grb2 binding domain of mSos1 is not required for downstream signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Regulation of Sos activity by intramolecular interactions

1 reference

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7 January 2021

N terminus of Sos1 Ras exchange factor: critical roles for the Dbl and pleckstrin homology domains

1 reference

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7 January 2021

The role of the PH domain in the signal-dependent membrane targeting of Sos.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Inhibition of mSOS-activity by binding of phosphatidylinositol 4,5-P2 to the mSOS pleckstrin homology domain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

EPS8 and E3B1 transduce signals from Ras to Rac

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

A murine CDC25/ras-GRF-related protein implicated in Ras regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Sensitivity of wild type and mutant ras alleles to Ras specific exchange factors: Identification of factor specific requirements

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Activation of R-Ras by Ras-guanine nucleotide-releasing factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Ras binding triggers ubiquitination of the Ras exchange factor Ras-GRF2.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Activation of the exchange factor Ras-GRF by calcium requires an intact Dbl homology domain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Oligomerization of DH domain is essential for Dbl-induced transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Dimerization of Cdc25p, the guanine-nucleotide exchange factor for Ras from Saccharomyces cerevisiae, and its interaction with Sdc25p.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Activation of the Ras-GRF/CDC25Mm exchange factor by lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Phosphorylation of serine 916 of Ras-GRF1 contributes to the activation of exchange factor activity by muscarinic receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Sites of phosphorylation by protein kinase A in CDC25Mm/GRF1, a guanine nucleotide exchange factor for Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The guanine nucleotide exchange factor CNrasGEF activates ras in response to cAMP and cGMP

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Ras-GRF, the activator of Ras, is expressed preferentially in mature neurons of the central nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The Ras Guanine nucleotide Exchange Factor CDC25Mm is present at the synaptic junction.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

A role for the Ras signalling pathway in synaptic transmission and long-term memory

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

CalDAG-GEFIII activation of Ras, R-ras, and Rap1.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The germinal center kinase gene and a novel CDC25-like gene are located in the vicinity of the PYGM gene on 11q13

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Distribution of ras guanyl releasing protein (RasGRP) mRNA in the adult rat central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Diacylglycerol kinase zeta regulates Ras activation by a novel mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Cytokines, virokines and the evolution of immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Guanine nucleotide exchange factors CalDAG-GEFI and CalDAG-GEFII are colocalized in striatal projection neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

HUGE: a database for human large proteins identified by Kazusa cDNA sequencing project

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification of a novel splice variant of C3G which shows tissue-specific expression

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Direct binding of p130(Cas) to the guanine nucleotide exchange factor C3G

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Fibroblast growth factor receptor-1-mediated endothelial cell proliferation is dependent on the Src homology (SH) 2/SH3 domain-containing adaptor protein Crk

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

IFN-gamma activates the C3G/Rap1 signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Engagement of the CrkL adapter in interleukin-5 signaling in eosinophils

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The Crk signaling pathway contributes to the bombesin-induced activation of the small GTPase Rap1 in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

CrkL mediates Ras-dependent activation of the Raf/ERK pathway through the guanine nucleotide exchange factor C3G in hematopoietic cells stimulated with erythropoietin or interleukin-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

C3G is tyrosine-phosphorylated after integrin-mediated cell adhesion in normal but not in Bcr/Abl expressing cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The adapter protein Crkl links Cbl to C3G after integrin ligation and enhances cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The association of CRKII with C3G can be regulated by integrins and defines a novel means to regulate the mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

A cell culture model for T lymphocyte clonal anergy

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Guanine-nucleotide exchange protein C3G activates JNK1 by a ras-independent mechanism. JNK1 activation inhibited by kinase negative forms of MLK3 and DLK mixed lineage kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Crk activation of JNK via C3G and R-Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

New exchange, new target

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

A family of cAMP-binding proteins that directly activate Rap1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Inhibition of thyrotropin-stimulated DNA synthesis by microinjection of inhibitors of cellular Ras and cyclic AMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Activation of the small G protein Rap1 in dog thyroid cells by both cAMP-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Expression of cAMP-regulated guanine nucleotide exchange factors in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

cAMP-GEFII is a direct target of cAMP in regulated exocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Cyclic AMP inhibits extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways by inhibiting Rap1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Characterization of GFR, a novel guanine nucleotide exchange factor for Rap1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

RA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding molecule (S-SCAM)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Membrane-associated guanylate kinase with inverted orientation (MAGI)-1/brain angiogenesis inhibitor 1-associated protein (BAP1) as a scaffolding molecule for Rap small G protein GDP/GTP exchange protein at tight junctions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The Rap1 GTPase functions as a regulator of morphogenesis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Sequence analysis identifies a ras-associating (RA)-like domain in the N-termini of band 4.1/JEF domains and in the Grb7/10/14 adapter family

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Transformation of BALB/3T3 cells with EJ/T24/H-ras oncogene inhibits adenylate cyclase response to beta-adrenergic agonist while increases muscarinic receptor dependent hydrolysis of inositol lipids

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification of PLC210, a Caenorhabditis elegans phospholipase C, as a putative effector of Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Role of the CDC25 homology domain of phospholipase Cepsilon in amplification of Rap1-dependent signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Phospholipase C(epsilon): a novel Ras effector

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

A novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Ras effectors: buying shares in Ras plc.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

ralGDS family members interact with the effector loop of ras p21.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

A novel potential effector of M-Ras and p21 Ras negatively regulates p21 Ras-mediated gene induction and cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

rsc: a novel oncogene with structural and functional homology with the gene family of exchange factors for Ral.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Ral-specific guanine nucleotide exchange factor activity opposes other Ras effectors in PC12 cells by inhibiting neurite outgrowth

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The Rgr oncogene (homologous to RalGDS) induces transformation and gene expression by activating Ras, Ral and Rho mediated pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification and characterization of R-ras3: a novel member of the RAS gene family with a non-ubiquitous pattern of tissue distribution

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Plasma membrane recruitment of RalGDS is critical for Ras-dependent Ral activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Stimulation of gene induction and cell growth by the Ras effector Rlf

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Synergistic activation of c-fos promoter activity by Raf and Ral GDP dissociation stimulator

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Ras-independent activation of Ral by a Ca(2+)-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Activation of the small GTPase Ral in platelets.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification and characterization of a calmodulin-binding domain in Ral-A, a Ras-related GTP-binding protein purified from human erythrocyte membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Chat, a Cas/HEF1-associated adaptor protein that integrates multiple signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification and characterization in Xenopus of XsmgGDS, a RalB binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Unique in vivo associations with SmgGDS and RhoGDI and different guanine nucleotide exchange activities exhibited by RhoA, dominant negative RhoA(Asn-19), and activated RhoA(Val-14).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The armadillo family of structural proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Three-dimensional structure of the armadillo repeat region of beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Structural view of the Ran-Importin beta interaction at 2.3 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The smg GDS-induced activation of smg p21 is initiated by cyclic AMP-dependent protein kinase-catalyzed phosphorylation of smg p21.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Cyclic AMP-dependent activation of Rap1b

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

How receptors talk to trimeric G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The Dbl oncogene product as a GDP/GTP exchange protein for the Rho family: its properties in comparison with those of Smg GDS

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

K-ras is essential for the development of the mouse embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Identification of darlin, a Dictyostelium protein with Armadillo-like repeats that binds to small GTPases and is important for the proper aggregation of developing cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Ras activation in human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

HER-2/neu signal transduction in human breast and ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Significance of the Grb2 and son of sevenless (Sos) proteins in human bladder cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

A novel family of Ras-binding domains

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Differential interactions of human Sos1 and Sos2 with Grb2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2802%2971047-7

7 January 2021

10.1016/S0079-6603(02)71047-7

Identifiers

DOI

3 references

https://doi.org/10.1016%2FS0079-6603%2802%2971047-7

27 March 2017

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12102558%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017