(Q27618579)

1

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A Arndt

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U Kutay

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A Wittinghofer

Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope

5

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language of work or name

English

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publication date

28 May 1999

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published in

Cell

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volume

97

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page(s)

635-46

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issue

5

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cites work

1 reference

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7 January 2021

HEAT repeats in the Huntington's disease protein

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7 January 2021

RanBP1 is crucial for the release of RanGTP from importin β-related nuclear transport factors

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7 January 2021

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

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7 January 2021

Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide

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7 January 2021

RanGAP1 induces GTPase activity of nuclear Ras-related Ran

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7 January 2021

Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1

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7 January 2021

Sequence and characterization of cytoplasmic nuclear protein import factor p97

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import

1 reference

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7 January 2021

Different binding domains for Ran-GTP and Ran-GDP/RanBP1 on nuclear import factor p97

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7 January 2021

The CCP4 suite: programs for protein crystallography

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7 January 2021

Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha

1 reference

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7 January 2021

Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line

1 reference

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7 January 2021

The nuclear transport factor karyopherin beta binds stoichiometrically to Ran-GTP and inhibits the Ran GTPase activating protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Disassembly of RanGTP-karyopherin beta complex, an intermediate in nuclear protein import.

1 reference

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7 January 2021

CRM1 is an export receptor for leucine-rich nuclear export signals

1 reference

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7 January 2021

The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88

1 reference

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7 January 2021

Isolation of a protein that is essential for the first step of nuclear protein import

1 reference

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7 January 2021

Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope

1 reference

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7 January 2021

A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus

1 reference

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7 January 2021

Importin provides a link between nuclear protein import and U snRNA export.

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7 January 2021

A novel class of RanGTP binding proteins

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7 January 2021

The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs

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7 January 2021

Interactions between HIV Rev and nuclear import and export factors: the Rev nuclear localisation signal mediates specific binding to human importin-beta

1 reference

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7 January 2021

A monoclonal antibody to the COOH-terminal acidic portion of Ran inhibits both the recycling of Ran and nuclear protein import in living cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Structural basis for the interaction of Ras with RalGDS

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

The nuclear pore-targeting complex binds to nuclear pores after association with a karyophile.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus

1 reference

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7 January 2021

Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Electron-density map interpretation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Ran-unassisted nuclear migration of a 97-kD component of nuclear pore-targeting complex

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Dynamic and equilibrium studies on the interaction of Ran with its effector, RanBP1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Ran-binding protein 1 (RanBP1) forms a ternary complex with Ran and karyopherin beta and reduces Ran GTPase-activating protein (RanGAP) inhibition by karyopherin beta

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Nucleocytoplasmic transport: the soluble phase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Raster3D Version 2.0. A program for photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Ras/Rap effector specificity determined by charge reversal

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

A repeating amino acid motif shared by proteins with diverse cellular roles

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

The C terminus of the nuclear RAN/TC4 GTPase stabilizes the GDP-bound state and mediates interactions with RCC1, RAN-GAP, and HTF9A/RANBP1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Major binding sites for the nuclear import receptor are the internal nucleoporin Nup153 and the adjacent nuclear filament protein Tpr

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Structural basis for molecular recognition between nuclear transport factor 2 (NTF2) and the GDP-bound form of the Ras-family GTPase Ran

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin beta-dependent nuclear localization signals

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

Crystal structure of RhoA-GDP and its functional implications

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021

The conserved amino-terminal domain of hSRP1 alpha is essential for nuclear protein import

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980774-6

7 January 2021