(Q27639792)

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Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A

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10 November 2019

Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A (English)

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10 November 2019

crystal structure

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protein structure

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Axel T. Brunger

2

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10 November 2019

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C Ostermeier

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1 February 1999

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10 November 2019

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10 November 2019

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10 November 2019

363-374

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10 November 2019

3

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10 November 2019

Identification of effector-activating residues of Gs alpha

1 reference

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Proteins regulating Ras and its relatives

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The GTPase superfamily: conserved structure and molecular mechanism

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Interactions of three domains distinguishing the Ras-related GTP-binding proteins Ypt1 and Sec4.

1 reference

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Two distinct Raf domains mediate interaction with Ras

1 reference

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1 reference

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The C2 domains of Rabphilin3A specifically bind phosphatidylinositol 4,5-bisphosphate containing vesicles in a Ca2+-dependent manner. In vitro characteristics and possible significance

1 reference

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7 January 2021

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rab3 mediates cortical granule exocytosis in the sea urchin egg.

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Biological and biochemical properties of human rasH genes mutated at codon 61.

1 reference

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An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

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C terminus of the small GTP-binding protein smg p25A contains two geranylgeranylated cysteine residues and a methyl ester

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The role of GTP-binding proteins in transport along the exocytic pathway

1 reference

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7 January 2021

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rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles

1 reference

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7 January 2021

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Rab proteins in regulated exocytosis

1 reference

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Phosphorylation of rabphilin-3A by Ca2+/calmodulin- and cAMP-dependent protein kinases in vitro.

1 reference

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GOR method for predicting protein secondary structure from amino acid sequence.

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7 January 2021

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7 January 2021

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RAB3 and synaptotagmin: the yin and yang of synaptic membrane fusion

1 reference

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7 January 2021

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The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion

1 reference

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The enigma of LIM domains

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Structural Basis for Activation of ARF GTPase

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Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

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Stereochemically restrained refinement of macromolecular structures

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7 January 2021

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Determination of macromolecular structures from anomalous diffraction of synchrotron radiation

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Protein structure comparison by alignment of distance matrices

1 reference

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Structural basis for the interaction of Ras with RalGDS

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Protein hydration observed by X-ray diffraction. Solvation properties of penicillopepsin and neuraminidase crystal structures.

1 reference

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Transcriptional synergy between LIM-homeodomain proteins and basic helix-loop-helix proteins: the LIM2 domain determines specificity

1 reference

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1 reference

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Phosphorylation of Rabphilin-3A by calmodulin-dependent protein kinase II.

1 reference

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Physical and functional interaction of rabphilin-3A with alpha-actinin

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1 reference

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Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C

1 reference

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The effector interactions of p21ras

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Docking of yeast vacuoles is catalyzed by the Ras-like GTPase Ypt7p after symmetric priming by Sec18p (NSF)

1 reference

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1 reference

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1 reference

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1 reference

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The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

1 reference

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1 reference

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1 reference

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The diversity of Rab proteins in vesicle transport

1 reference

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1 reference

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7 January 2021

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Processing of X-ray diffraction data collected in oscillation mode

1 reference

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Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

1 reference

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1 reference

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1 reference

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1 reference

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Rab GTPases: master regulators of membrane trafficking

1 reference

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inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A site on rod G protein alpha subunit that mediates effector activation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The LIM domain is a modular protein-binding interface

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin

1 reference

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7 January 2021

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inferred from DOI database lookup

Rab proteins and the road maps for intracellular transport

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

G protein mechanisms: insights from structural analysis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

G proteins, effectors and GAPs: structure and mechanism

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct structural elements of rab5 define its functional specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980549-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of the adenylyl cyclase activator Gsalpha

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980549-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980549-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of ras proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980549-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Defining the functions of trans-SNARE pairs

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Resolution of phase ambiguity in macromolecular crystallography

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980549-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980549-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Vesicular transport. Sticky fingers grab a lipid.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980549-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The use of anomalous scattering effects to phase diffraction patterns from macromolecules

1 reference

19 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1107/S0567739480001817

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10.1016/S0092-8674(00)80549-8

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Europe PubMed Central

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10 November 2019

OpenCitations bibliographic resource ID

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OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10025402%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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