(Q22254750)

Rap guanine nucleotide exchange factor 2

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Muscle RAS oncogene homolog

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Rap guanine nucleotide exchange factor 5

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diacylglycerol binding

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Journal of Biological Chemistry

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J F Rebhun

1

J F

Rebhun

1 reference

28 March 2023

A F Castro

series ordinal

2

author given names

A F

author last names

Castro

1 reference

28 March 2023

L A Quilliam

series ordinal

3

author given names

L A

author last names

Quilliam

1 reference

28 March 2023

language of work or name

English

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publication date

10 November 2000

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published in

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volume

275

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issue

45

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page(s)

34901-8

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cites work

Increasing complexity of Ras signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Mutations in the gene encoding KRIT1, a Krev-1/rap1a binding protein, cause cerebral cavernous malformations (CCM1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Truncating mutations in CCM1, encoding KRIT1, cause hereditary cavernous angiomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Identification and characterization of R-ras3: a novel member of the RAS gene family with a non-ubiquitous pattern of tissue distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Novel small GTPase M-Ras participates in reorganization of actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

SmgGDS stabilizes nucleotide-bound and -free forms of the Rac1 GTP-binding protein and stimulates GTP/GDP exchange through a substituted enzyme mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

A repeating amino acid motif shared by proteins with diverse cellular roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Proteins regulating Ras and its relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

The structural basis of the activation of Ras by Sos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

The role of the PH domain in the signal-dependent membrane targeting of Sos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

A family of cAMP-binding proteins that directly activate Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

A novel family of Ras-binding domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Identification of residues of the H-ras protein critical for functional interaction with guanine nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Plasma membrane recruitment of RalGDS is critical for Ras-dependent Ral activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Characterization of GFR, a novel guanine nucleotide exchange factor for Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding molecule (S-SCAM)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

The guanine nucleotide exchange factor CNrasGEF activates ras in response to cAMP and cGMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Identification and characterization in Xenopus of XsmgGDS, a RalB binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Emerging components of the Crk oncogene product: the first identified adaptor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Activity of Rap1 is regulated by bombesin, cell adhesion, and cell density in NIH3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Sequence analysis identifies a ras-associating (RA)-like domain in the N-termini of band 4.1/JEF domains and in the Grb7/10/14 adapter family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Raf-like Ras/Rap-binding domains in RGS12- and still-life-like signalling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

Calcitonin stimulates growth of human prostate cancer cells through receptor-mediated increase in cyclic adenosine 3',5'-monophosphates and cytoplasmic Ca2+ transients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

7 January 2021

Structural and biochemical analysis of Ras-effector signaling via RalGDS

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

7 January 2021

The Ras superfamily of GTPases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

7 January 2021

Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005327200

7 January 2021