(Q38357532)

English

Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12592335%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12592335%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

apoptotic process

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1 reference

based on heuristic

inferred from title

histone acetylation

1 reference

based on heuristic

inferred from title

Kellie J Archer

10

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31 October 2019

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Klisovic MI

1

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31 October 2019

Maghraby EA

2

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31 October 2019

Parthun MR

3

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31 October 2019

Guimond M

4

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31 October 2019

Sklenar AR

5

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31 October 2019

Whitman SP

6

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31 October 2019

Chan KK

7

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31 October 2019

Murphy T

8

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31 October 2019

Anon J

9

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31 October 2019

Rush LJ

11

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31 October 2019

Plass C

12

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31 October 2019

Grever MR

13

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31 October 2019

Byrd JC

14

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31 October 2019

Marcucci G

15

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31 October 2019

publication date

1 February 2003

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31 October 2019

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31 October 2019

17

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31 October 2019

2

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31 October 2019

350-358

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31 October 2019

https://scigraph.springernature.com/pub.10.1038/sj.leu.2402776

0 references

Molecular and clinical advances in core binding factor primary acute myeloid leukemia: a paradigm for translational research in malignant hematology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

Histone deacetylases and transcriptional therapy with their inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

Action of FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum no. 968, on Ha-ras transformed NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

Quantification of CBFbeta/MYH11 fusion transcript by real time RT-PCR in patients with INV(16) acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

Gene silencing. Methylation meets acetylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

DNA methylation and chromatin modification.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

The drosophila MSL complex acetylates histone H4 at lysine 16, a chromatin modification linked to dosage compensation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

21 January 2018

FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

7 January 2021

based on heuristic

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Gene expression of interleukin-3 and granulocyte macrophage colony-stimulating factor in circulating CD4+ T cells in acute severe asthma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402776

7 January 2021

based on heuristic

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Identifiers

10.1038/SJ.LEU.2402776

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31 October 2019

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31 October 2019

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