(Q38358598)

2 September 2017

title

Repair of the mutagenic DNA oxidation product, 5-formyluracil (English)

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2 September 2017

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ChEBI release 2020-05-28

Pingfang Liu

1

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2 September 2017

Artur Burdzy

series ordinal

2

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2 September 2017

Lawrence C Sowers

series ordinal

3

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2 September 2017

publication date

1 February 2003

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2 September 2017

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2 September 2017

volume

2

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2 September 2017

issue

2

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2 September 2017

page(s)

199-210

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Oxidants, antioxidants, and the degenerative diseases of aging

2 September 2017

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DNA damage metabolism and aging

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Ionizing radiation and tritium transmutation both cause formation of 5-hydroxymethyl-2'-deoxyuridine in cellular DNA.

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7 January 2021

5-Formyldeoxyuridine: a new type of DNA damage induced by ionizing radiation and its mutagenicity to salmonella strain TA102.

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7 January 2021

Measurement of Oxidative Damage at Pyrimidine Bases in γ-Irradiated DNA

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7 January 2021

Site directed substitution of 5-hydroxymethyluracil for thymine in replicating phi X-174am3 DNA via synthesis of 5-hydroxymethyl-2'-deoxyuridine-5'-triphosphate

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7 January 2021

Replication of DNA templates containing 5-formyluracil, a major oxidative lesion of thymine in DNA

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7 January 2021

Replication in vitro and cleavage by restriction endonuclease of 5-formyluracil- and 5-hydroxymethyluracil-containing oligonucleotides

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7 January 2021

Mutagenic effects of 5-formyluracil on a plasmid vector during replication in Escherichia coli

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7 January 2021

Mutations induced by 5-formyl-2'-deoxyuridine in Escherichia coli include base substitutions that can arise from mispairs of 5-formyluracil with guanine, cytosine and thymine

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7 January 2021

Induction of T --> G and T --> A transversions by 5-formyluracil in mammalian cells

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7 January 2021

Cellular effects of 5-formyluracil in DNA.

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7 January 2021

The mutations induced by oxidatively damaged nucleotides, 5-formyl-dUTP and 5-hydroxy-dCTP,in Escherichia coli

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7 January 2021

5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism

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7 January 2021

A proposed mechanism for the mutagenicity of 5-formyluracil

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7 January 2021

Substrate and mispairing properties of 5-formyl-2'-deoxyuridine 5'-triphosphate assessed by in vitro DNA polymerase reactions

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7 January 2021

Oxidation of thymine to 5-formyluracil in DNA promotes misincorporation of dGMP and subsequent elongation of a mismatched primer terminus by DNA polymerase

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7 January 2021

Oxidation of thymine to 5-formyluracil in DNA: mechanisms of formation, structural implications, and base excision by human cell free extracts

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7 January 2021

Synthesis of oligonucleotides containing the oxidatively modified kappaB site: unique binding affinity to the NFkappaB p50 homodimer

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7 January 2021

Nucleosides and nucleotides. 131. Synthesis and properties of oligonucleotides containing 5-formyl-2'-deoxyuridine

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7 January 2021

Approaches to the affinity labelling ofE. coliDNA-dependent RNA polymerase

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7 January 2021

Novel modification of 5-formyluracil by cysteine derivatives in aqueous solution

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7 January 2021

Excision of DNA adducts of nitrogen mustards by bacterial and mammalian 3-methyladenine-DNA glycosylases.

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7 January 2021

Identification of repair enzymes for 5-formyluracil in DNA. Nth, Nei, and MutM proteins of Escherichia coli

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7 January 2021

Role of the Escherichia coli and human DNA glycosylases that remove 5-formyluracil from DNA in the prevention of mutations

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7 January 2021

Enzymatic repair of 5-formyluracil. I. Excision of 5-formyluracil site-specifically incorporated into oligonucleotide substrates by alka protein (Escherichia coli 3-methyladenine DNA glycosylase II)

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7 January 2021

Enzymatic repair of 5-formyluracil. II. Mismatch formation between 5-formyluracil and guanine during dna replication and its recognition by two proteins involved in base excision repair (AlkA) and mismatch repair (MutS).

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7 January 2021

Enzymatic release of 5-formyluracil by mammalian liver extracts from DNA irradiated with ionizing radiation

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7 January 2021

An N -Glycosidase from Escherichia coli That Releases Free Uracil from DNA Containing Deaminated Cytosine Residues

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7 January 2021

A new class of uracil-DNA glycosylases related to human thymine-DNA glycosylase

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7 January 2021

3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase

1 reference

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7 January 2021

The role of the Escherichia coli mug protein in the removal of uracil and 3,N(4)-ethenocytosine from DNA.

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7 January 2021

Escherichia coli double-strand uracil-DNA glycosylase: involvement in uracil-mediated DNA base excision repair and stimulation of activity by endonuclease IV.

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7 January 2021

Two amino acid replacements change the substrate preference of DNA mismatch glycosylase Mig.MthI from T/G to A/G.

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7 January 2021

Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase

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7 January 2021

Kinetics of the action of thymine DNA glycosylase

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7 January 2021

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

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7 January 2021

MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

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7 January 2021

Solid phase synthesis and restriction endonuclease cleavage of oligodeoxynucleotides containing 5-(hydroxymethyl)-cytosine

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7 January 2021

Quantification of 5-(hydroxymethyl)uracil in DNA by gas chromatography/mass spectrometry: problems and solutions.

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7 January 2021

Correlation between sequence-dependent glycosylase repair and the thermal stability of oligonucleotide duplexes containing 1, N6-ethenoadenine

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7 January 2021

Conformation and proton configuration of pyrimidine deoxynucleoside oxidation damage products in water

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7 January 2021

Substrate recognition by a family of uracil-DNA glycosylases: UNG, MUG, and TDG.

1 reference

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7 January 2021

Identification of 5-formyluracil DNA glycosylase activity of human hNTH1 protein

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7 January 2021

The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900198-2

7 January 2021

Repair of DNA containing the oxidatively-damaged base, 8-oxoguanine

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900198-2

7 January 2021

Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in vivo functions

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https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900198-2

7 January 2021

10.1016/S1568-7864(02)00198-2

Identifiers

DOI

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2 September 2017

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