(Q38359904)

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Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma ) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its anti-tumorigenic activity.

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12475986%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma ) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its anti-tumorigenic activity (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12475986%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

Seung Joon Baek

1

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15 December 2019

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Leigh C Wilson

2

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15 December 2019

Linda C Hsi

3

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15 December 2019

Thomas E Eling

4

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15 December 2019

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9 December 2002

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15 December 2019

Journal of Biological Chemistry

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15 December 2019

278

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15 December 2019

8

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15 December 2019

5845-5853

1 reference

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15 December 2019

Peroxisome proliterator-activated receptors, orphans with ligands and functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

The organization, promoter analysis, and expression of the human PPARgamma gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

PPARgamma3 mRNA: a distinct PPARgamma mRNA subtype transcribed from an independent promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Activation of the PPAR pathway induces apoptosis and COX-2 inhibition in HT-29 human colon cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Troglitazone inhibits growth of MCF-7 breast carcinoma cells by targeting G1 cell cycle regulators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Ligands of peroxisome proliferator-activated receptor-gamma induce apoptosis in AR42J cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Peroxisome proliferator-activated receptor gamma ligands inhibit mitogenic induction of p21(Cip1) by modulating the protein kinase Cdelta pathway in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Troglitazone upregulates nitric oxide synthesis in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Troglitazone induces apoptosis via the p53 and Gadd45 pathway in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Troglitazone, an antidiabetic agent, inhibits cholesterol biosynthesis through a mechanism independent of peroxisome proliferator-activated receptor-gamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Troglitazone suppresses cell growth of myeloid leukemia cell lines by induction of p21WAF1/CIP1 cyclin-dependent kinase inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Inhibition of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by troglitazone: a peroxisome proliferator-activated receptor-gamma (PPARgamma)-independent, antioxidant-related mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

The transcription factor EGR-1 directly transactivates the fibronectin gene and enhances attachment of human glioblastoma cell line U251.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Role of EGR-1 in thapsigargin-inducible apoptosis in the melanoma cell line A375-C6.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Role of Egr-1 gene expression in B cell receptor-induced apoptosis in an immature B cell lymphoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Early growth response-1-dependent apoptosis is mediated by p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

EGR-1, a UV-inducible gene in p53(-/-) mouse cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Molecular cloning and characterization of human nonsteroidal anti-inflammatory drug-activated gene promoter. Basal transcription is mediated by Sp1 and Sp3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Peroxisome proliferator-activated receptor gamma induces growth arrest and differentiation markers of human colon cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Induction of Egr-1 expression by the retinoid AHPN in human lung carcinoma cells is dependent on activated ERK1/2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Prostaglandins promote and block adipogenesis through opposing effects on peroxisome proliferator-activated receptor gamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

15-lipoxygenase-1 metabolites down-regulate peroxisome proliferator-activated receptor gamma via the MAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Activation of peroxisome proliferator-activated receptor-gamma stimulates the growth arrest and DNA-damage inducible 153 gene in non-small cell lung carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Troglitazone activates p21Cip/WAF1 through the ERK pathway in HCT15 human colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Bisphenol A diglycidyl ether induces apoptosis in tumour cells independently of peroxisome proliferator-activated receptor-gamma, in caspase-dependent and -independent manners

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Functional characterization of a non-AUUUA AU-rich element from the c-jun proto-oncogene mRNA: evidence for a novel class of AU-rich elements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Adhesion-dependent regulation of an A+U-rich element-binding activity associated with AUF1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Combinations of ERK and p38 MAPK inhibitors ablate tumor necrosis factor-alpha (TNF-alpha ) mRNA induction. Evidence for selective destabilization of TNF-alpha transcripts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Transcription factor EGR-1 suppresses the growth and transformation of human HT-1080 fibrosarcoma cells by induction of transforming growth factor beta 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Activators of the nuclear receptor PPARgamma enhance colon polyp formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Troglitazone and rosiglitazone induce apoptosis of vascular smooth muscle cells through an extracellular signal-regulated kinase-independent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Effects of troglitazone on cellular differentiation, insulin signaling, and glucose metabolism in cultured human skeletal muscle cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208394200

21 January 2018

Identifiers

10.1074/JBC.M208394200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12475986%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12475986%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

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