(Q38360068)

2 September 2017

title

A small molecule Abl kinase inhibitor induces differentiation of Abelson virus-transformed pre-B cell lines (English)

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2 September 2017

Stefan A Muljo

1

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2 September 2017

Mark S Schlissel

series ordinal

2

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2 September 2017

language of work or name

English

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publication date

2 December 2002

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2 September 2017

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2 September 2017

volume

4

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2 September 2017

issue

1

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2 September 2017

page(s)

31-37

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Down-regulation of RAG1 and RAG2 gene expression in PreB cells after functional immunoglobulin heavy chain rearrangement

2 September 2017

cites work

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7 January 2021

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

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7 January 2021

Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

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7 January 2021

In vitro transformation of lymphoid cells by Abelson murine leukemia virus

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7 January 2021

B-lineage differentiation in normal and transformed cells and the microenvironment that supports it.

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7 January 2021

Autoinhibition of c-Abl

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7 January 2021

Organization and reorganization of immunoglobulin genes in A-MuLV-transformed cells: Rearrangement of heavy but not light chain genes

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7 January 2021

Transcription factor NF-kappa B regulates Ig lambda light chain gene rearrangement

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7 January 2021

Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription

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7 January 2021

The v-abl tyrosine kinase negatively regulates NF-kappa B/Rel factors and blocks kappa gene transcription in pre-B lymphocytes

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7 January 2021

An active v-abl protein tyrosine kinase blocks immunoglobulin light-chain gene rearrangement

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7 January 2021

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

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7 January 2021

Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro

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7 January 2021

Changes in gene expression profiles in developing B cells of murine bone marrow

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7 January 2021

IL-2 receptor alpha chain expression during early B lymphocyte differentiation

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7 January 2021

IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development

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7 January 2021

Interleukin-7 induces N-myc and c-myc expression in normal precursor B lymphocytes

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7 January 2021

Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator

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7 January 2021

In vivo occupancy of the kappa light chain enhancers in primary pro- and pre-B cells: a model for kappa locus activation

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7 January 2021

Overexpression of RelA causes G1 arrest and apoptosis in a pro-B cell line

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7 January 2021

RNA interference: the new somatic cell genetics?

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7 January 2021

Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo

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7 January 2021

Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor

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7 January 2021

Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene loci

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7 January 2021

Sensing of intermediates in V(D)J recombination by ATM.

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7 January 2021

A sense-abl response?

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7 January 2021

p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement.

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7 January 2021

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

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7 January 2021

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

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7 January 2021

Bone Marrow B Lymphocyte Development in c-abl-Deficient Mice

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7 January 2021

A novel human gene closely related to the abl proto-oncogene

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7 January 2021

Essential roles for the Abl and Arg tyrosine kinases in neurulation

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7 January 2021

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

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7 January 2021

SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1

1 reference

7 January 2021

Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B.

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7 January 2021

Spi-B can functionally replace PU.1 in myeloid but not lymphoid development

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7 January 2021

Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

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7 January 2021

PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction

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7 January 2021

Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE).

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7 January 2021

PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity

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7 January 2021

PU.1 is a component of a multiprotein complex which binds an essential site in the murine immunoglobulin lambda 2-4 enhancer

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7 January 2021

Assembly requirements of PU.1-Pip (IRF-4) activator complexes: inhibiting function in vivo using fused dimers

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7 January 2021

Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function

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7 January 2021

Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement

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7 January 2021

The Ig(kappa) enhancer influences the ratio of Ig(kappa) versus Ig(lambda) B lymphocytes

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7 January 2021

Continuing kappa-gene rearrangement in a cell line transformed by Abelson murine leukemia virus

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7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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7 January 2021

Cluster analysis and display of genome-wide expression patterns

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7 January 2021

Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

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7 January 2021

V(D)J recombinase activity in a subset of germinal center B lymphocytes

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7 January 2021

PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors

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7 January 2021

Identifiers

DOI

10.1038/NI870

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Dimensions Publication ID

2 September 2017

1011465199

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