(Q38360461)

2 September 2017

title

A dominant negative mutant beta 2-microglobulin blocks the extracellular folding of a major histocompatibility complex class I heavy chain (English)

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2 September 2017

Dawn M Hill

1

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2 September 2017

Tina Kasliwal

2

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2 September 2017

Elie Schwarz

3

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2 September 2017

Andrea M Hebert

4

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2 September 2017

Trina Chen

5

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2 September 2017

Elena Gubina

6

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2 September 2017

Lei Zhang

7

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2 September 2017

Steven Kozlowski

8

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2 September 2017

language of work or name

English

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publication date

25 November 2002

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

278

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2 September 2017

issue

8

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2 September 2017

page(s)

5630-5638

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Antigen recognition by class I-restricted T lymphocytes

2 September 2017

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Mutant HLA-A201 heavy chains with lowered affinity for beta 2m are transported after growth at reduced temperatures

21 January 2018

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Beta 2-microglobulin is not required for cell surface expression of the murine class I histocompatibility antigen H-2Db or of a truncated H-2Db

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Functionally conformed free class I heavy chains exist on the surface of beta 2 microglobulin negative cells

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Beta 2-microglobulin with an endoplasmic reticulum retention signal increases the surface expression of folded class I major histocompatibility complex molecules.

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Low temperature and peptides favor the formation of class I heterodimers on RMA-S cells at the cell surface

21 January 2018

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21 January 2018

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Dissociation and exchange of the beta 2-microglobulin subunit of HLA-A and HLA-B antigens

21 January 2018

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21 January 2018

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Defective assembly of class I major histocompatibility complex molecules in an embryonic cell line

21 January 2018

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Modification of cysteine residues in vitro and in vivo affects the immunogenicity and antigenicity of major histocompatibility complex class I-restricted viral determinants

21 January 2018

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An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes.

21 January 2018

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Serum angiotensin-1 converting enzyme activity processes a human immunodeficiency virus 1 gp160 peptide for presentation by major histocompatibility complex class I molecules

21 January 2018

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21 January 2018

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21 January 2018

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Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand

21 January 2018

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Differential association of beta2-microglobulin mutants with MHC class I heavy chains and structural analysis demonstrate allele-specific interactions.

21 January 2018

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21 January 2018

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Empty MHC class I molecules come out in the cold

21 January 2018

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How do peptides associate with MHC class I molecules?

21 January 2018

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MHC class I recognition by NK receptors in the Ly49 family is strongly influenced by the beta 2-microglobulin subunit.

21 January 2018

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Novel CD8+ T cell antagonists based on beta 2-microglobulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208381200

Dissociation of beta 2-microglobulin leads to the accumulation of a substantial pool of inactive class I MHC heavy chains on the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208381200

Extensive peptide ligand exchange by surface class I major histocompatibility complex molecules independent of exogenous beta 2-microglobulin

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M208381200

The role of beta 2-microglobulin in peptide binding by class I molecules

21 January 2018

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Reassociation with beta 2-microglobulin is necessary for Kb class I major histocompatibility complex binding of exogenous peptides

21 January 2018

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Exogenous beta 2-microglobulin is required for antigenic peptide binding to isolated class I major histocompatibility complex molecules

21 January 2018

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Extracellular processing of peptide antigens that bind class I major histocompatibility molecules

21 January 2018

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Serum proteases alter the antigenicity of peptides presented by class I major histocompatibility complex molecules

21 January 2018

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The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

21 January 2018

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Excess β2 microglobulin promoting functional peptide association with purified soluble class I MHC molecules

21 January 2018

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Structural requirements for the peptide-induced conformational change of free major histocompatibility complex class I heavy chains

21 January 2018

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The isolated major histocompatibility complex class I alpha3 domain binds beta2m and CD8alphaalpha dimers

21 January 2018

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The effect of human beta2-microglobulin on major histocompatibility complex I peptide loading and the engineering of a high affinity variant. Implications for peptide-based vaccines

21 January 2018

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Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors

21 January 2018

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The conformational flexibility of class I H-2 molecules as revealed by anti-peptide antibodies specific for intracytoplasmic determinants: Differential reactivity of β2-microglobulin “bound” and “free” H-2Kb heavy chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208381200

Binding of the natural killer cell inhibitory receptor Ly49A to its major histocompatibility complex class I ligand. Crucial contacts include both H-2Dd AND beta 2-microglobulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208381200

21 January 2018

Identifiers

DOI

10.1074/JBC.M208381200

1 reference

2 September 2017

1 reference