(Q38380293)

2 September 2017

1 reference

title

The osteochondral interface as a gradient tissue: from development to the fabrication of gradient scaffolds for regenerative medicine (English)

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2 September 2017

main subject

regenerative medicine

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Lorenzo Moroni

3

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Clemens van Blitterswijk

object named as

Clemens Van Blitterswijk

series ordinal

2

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author name string

Andrea Di Luca

series ordinal

1

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2 September 2017

publication date

16 March 2015

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Birth Defects Research Part C: Embryo Today Reviews

2 September 2017

published in

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2 September 2017

volume

105

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2 September 2017

issue

1

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2 September 2017

page(s)

34-52

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Stem cell therapies for knee cartilage repair: the current status of preclinical and clinical studies

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

The Maturation of Synthetic Scaffolds for Osteochondral Donor Sites of the Knee: An MRI and T2-Mapping Analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Articular cartilage evaluation after TruFit plug implantation analyzed by delayed gadolinium-enhanced MRI of cartilage (dGEMRIC).

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.21092

Extracellular matrix scaffolds for cartilage and bone regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Articular cartilage: structure, injuries and review of management

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Bone formation via cartilage models: the "borderline" chondrocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Enhancing bioactivity of chitosan film for osteogenesis and wound healing by covalent immobilization of BMP-2 or FGF-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

TGF-β and BMP signaling in osteoblast differentiation and bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Regulatory mechanisms in the pathways of cartilage and bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

A pilot study of the use of an osteochondral scaffold plug for cartilage repair in the knee and how to deal with early clinical failures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Regeneration of a goat femoral head using a tissue-specific, biphasic scaffold fabricated with CAD/CAM technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Osteochondral interface regeneration of rabbit mandibular condyle with bioactive signal gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Osteochondral interface tissue engineering using macroscopic gradients of bioactive signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Evaluation of a press-fit osteochondral poly(ester-urethane) scaffold in a rabbit defect model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Matrix control of stem cell fate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Volume increase in growth plate chondrocytes during hypertrophy: the contribution of organic osmolytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Smad3 induces chondrogenesis through the activation of SOX9 via CREB-binding protein/p300 recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Expression and function of BMP3 during chick limb development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Appearance and persistence of fibronectin in cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

The control of chondrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Spatial regulation of human mesenchymal stem cell differentiation in engineered osteochondral constructs: effects of pre-differentiation, soluble factors and medium perfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Control of osteoblast function and regulation of bone mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

The development of articular cartilage: evidence for an appositional growth mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Multiphasic collagen fibre-PLA composites seeded with human mesenchymal stem cells for osteochondral defect repair: an in vitro study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Autologous osteochondral mosaicplasty or TruFit plugs for cartilage repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Multiphasic construct studied in an ectopic osteochondral defect model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Bioactive stratified polymer ceramic-hydrogel scaffold for integrative osteochondral repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Synthetic resorbable scaffolds for the treatment of isolated patellofemoral cartilage defects in young patients: magnetic resonance imaging and clinical evaluation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Repair of osteochondral defects with biphasic cartilage-calcium polyphosphate constructs in a sheep model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Secreted antagonists of the Wnt signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Wnt signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Novel nano-composite multilayered biomaterial for osteochondral regeneration: a pilot clinical trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Chronic posttraumatic cartilage lesion of the knee treated with an acellular osteochondral-regenerating implant: case history with rehabilitation guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Clinical results and MRI evolution of a nano-composite multilayered biomaterial for osteochondral regeneration at 5 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Developmental regulation of the growth plate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Treatment with ephrin B2 positively impacts the abnormal metabolism of human osteoarthritic chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

A biomimetic multi-layered collagen-based scaffold for osteochondral repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Epidemiological profile of symptomatic osteoarthritis in older adults: a population based study in Dicomano, Italy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Osteochondral tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

The potential of encapsulating "raw materials" in 3D osteochondral gradient scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

3D fiber-deposited scaffolds for tissue engineering: influence of pores geometry and architecture on dynamic mechanical properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Evaluation of multiphase implants for repair of focal osteochondral defects in goats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Gradients in bone morphogenetic protein-related gene expression across the growth plate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Influence of cyclic loading on the nutrition of articular cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

The interaction of the zone of calcified cartilage and subchondral bone in osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Hypertrophic chondrocytes. The terminal stage of differentiation in the chondrogenic cell lineage?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Osteochondral tissue engineering approaches for articular cartilage and subchondral bone regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

BMP signaling in the cartilage growth plate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Articular cartilage chondrons: form, function and failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Fate of large donor site defects in osteochondral transfer procedures in the knee joint with and without TruFit Plugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Simultaneous regeneration of articular cartilage and subchondral bone induced by spatially presented TGF-beta and BMP-4 in a bilayer affinity binding system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Vulnerability of the superficial zone of immature articular cartilage to compressive injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

In vitro generation of osteochondral composites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Engineered osteochondral grafts using biphasic composite solid free-form fabricated scaffolds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Interplay between cartilage and subchondral bone contributing to pathogenesis of osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

A three-dimensional osteochondral composite scaffold for articular cartilage repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Osteochondral tissue engineering with biphasic scaffold: current strategies and techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Measurement of pH and ionic composition of pericellular sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Strategies and applications for incorporating physical and chemical signal gradients in tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Microsphere-based seamless scaffolds containing macroscopic gradients of encapsulated factors for tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Three-dimensional plotted scaffolds with controlled pore size gradients: Effect of scaffold geometry on mechanical performance and cell seeding efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Repair of osteochondral defects with hyaluronan- and polyester-based scaffolds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Stem cell- and scaffold-based tissue engineering approaches to osteochondral regenerative medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Stiffness gradients mimicking in vivo tissue variation regulate mesenchymal stem cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

IGF-1R signaling in chondrocytes modulates growth plate development by interacting with the PTHrP/Ihh pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Polymer scaffolds fabricated with pore-size gradients as a model for studying the zonal organization within tissue-engineered cartilage constructs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Design of porous scaffolds for cartilage tissue engineering using a three-dimensional fiber-deposition technique.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Wnt influence on chondrocyte differentiation and cartilage function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Analysis of the mineral composition of the human calcified cartilage zone

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Nutrient gradients in engineered cartilage: metabolic kinetics measurement and mass transfer modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Lubricin expression in human osteoarthritic knee meniscus and synovial fluid: A morphological, immunohistochemical and biochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

A novel nano-composite multi-layered biomaterial for treatment of osteochondral lesions: technique note and an early stability pilot clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Osteochondral regeneration using a novel aragonite-hyaluronate bi-phasic scaffold in a goat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

Novel nanostructured scaffold for osteochondral regeneration: pilot study in horses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.21092

21 January 2018

Identifiers

DOI

10.1002/BDRC.21092

1 reference

2 September 2017

1 reference