(Q38400509)

2 September 2017

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title

Effects of ketone bodies in Alzheimer's disease in relation to neural hypometabolism, β-amyloid toxicity, and astrocyte function (English)

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2 September 2017

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Helle S. Waagepetersen

series ordinal

3

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2 September 2017

1

Leif Hertz

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2 September 2017

Ye Chen

2

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2 September 2017

language of work or name

English

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publication date

23 April 2015

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Journal of Neurochemistry

2 September 2017

published in

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2 September 2017

volume

134

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2 September 2017

issue

1

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2 September 2017

page(s)

7-20

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Activation of PARP by oxidative stress induced by β-amyloid: implications for Alzheimer's disease

2 September 2017

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Astrocytic glycogenolysis: mechanisms and functions

21 January 2018

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The alternatively spliced Kunitz protease inhibitor domain alters amyloid beta protein precursor processing and amyloid beta protein production in cultured cells

21 January 2018

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First clinical data of the neuroprotective effects of nasal insulin application in patients with Alzheimer's disease

21 January 2018

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Abnormalities of Glucose Metabolism in Alzheimer's Disease

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A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease

21 January 2018

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21 January 2018

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21 January 2018

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Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

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Glucose deprivation-induced cytotoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells.

21 January 2018

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Greater medial temporal hypometabolism and lower cortical amyloid burden in ApoE4-positive AD patients

21 January 2018

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21 January 2018

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21 January 2018

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Medium-chain triglyceride ketogenic diet, an effective treatment for drug-resistant epilepsy and a comparison with other ketogenic diets

21 January 2018

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Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons.

21 January 2018

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Vasoactive intestinal polypeptide induces glycogenolysis in mouse cortical slices: a possible regulatory mechanism for the local control of energy metabolism

21 January 2018

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Noradrenergic mechanisms in neurodegenerative diseases: a theory

21 January 2018

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Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

21 January 2018

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Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism

21 January 2018

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21 January 2018

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21 January 2018

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A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer's disease

21 January 2018

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Neuronal and astrocytic metabolism in a transgenic rat model of Alzheimer's disease

21 January 2018

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Norepinephrine: a neuromodulator that boosts the function of multiple cell types to optimize CNS performance

21 January 2018

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Brain Metabolism during Fasting*

21 January 2018

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Regulation of hexokinase binding to VDAC

21 January 2018

1 reference

Effects of γ-Aminobutyric acid transporter 1 inhibition by tiagabine on brain glutamate and γ-Aminobutyric acid metabolism in the anesthetized rat In vivo

21 January 2018

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21 January 2018

1 reference

An intact hydrophobic N-terminal sequence is critical for binding of rat brain hexokinase to mitochondria

21 January 2018

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Neurofibrillary degeneration of cholinergic and noncholinergic neurons of the basal forebrain in Alzheimer's disease

21 January 2018

1 reference

Effects of beta-hydroxybutyrate on cognition in memory-impaired adults

21 January 2018

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21 January 2018

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21 January 2018

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Minimally invasive biomarker confirms glial activation present in Alzheimer's disease: a preliminary study

21 January 2018

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Functional MRI and neural responses in a rat model of Alzheimer's disease.

21 January 2018

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21 January 2018

1 reference

Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA.

21 January 2018

1 reference

Ciliary neurotrophic factor (CNTF) activation of astrocytes decreases spreading depolarization susceptibility and increases potassium clearance

21 January 2018

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Broiler chickens (Ross strain) lack insulin-responsive glucose transporter GLUT4 and have GLUT8 cDNA.

21 January 2018

1 reference

An immunochemical study of the pyruvate dehydrogenase deficit in Alzheimer's disease brain

21 January 2018

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Antimicrobial effects of virgin coconut oil and its medium-chain fatty acids on Clostridium difficile

21 January 2018

1 reference

The mitochondrial voltage-dependent anion channel 1 in tumor cells.

21 January 2018

1 reference

Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity

21 January 2018

1 reference

Does Alzheimer's disease begin in the brainstem?

21 January 2018

1 reference

Seizures and epileptiform activity in early Alzheimer disease: how hard should we be looking?

21 January 2018

1 reference

Noradrenaline induced stimulation of oxidative metabolism in astrocytes but not in neurons in primary cultures

21 January 2018

1 reference

Stimulation of energy metabolism by alpha-adrenergic agonists in primary cultures of astrocytes

21 January 2018

1 reference

Autopsy samples of Alzheimer's cortex show increased peroxidation in vitro

21 January 2018

1 reference

Glucose phosphorylation and mitochondrial binding are required for the protective effects of hexokinases I and II.

21 January 2018

1 reference

Detection of changes in the locus coeruleus in patients with mild cognitive impairment and Alzheimer's disease: high-resolution fast spin-echo T1-weighted imaging.

21 January 2018

1 reference

Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo.

21 January 2018

1 reference

Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

21 January 2018

1 reference

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21 January 2018

1 reference

Treatment of Parkinson disease with diet-induced hyperketonemia: a feasibility study.

21 January 2018

1 reference

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21 January 2018

1 reference

Regulated Exocytosis in Astrocytes is as Slow as the Metabolic Availability of Gliotransmitters: Focus on Glutamate and ATP.

21 January 2018

1 reference

Ketone bodies, potential therapeutic uses

21 January 2018

1 reference

Why are astrocytes important?

21 January 2018

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On the role of calcium ions in the regulation of glycogenolysis in mouse brain cortical slices

21 January 2018

1 reference

A multicenter study of the efficacy of the ketogenic diet.

21 January 2018

1 reference

Metabolic distinction between vesicular and cytosolic GABA in cultured GABAergic neurons using 13C magnetic resonance spectroscopy

21 January 2018

1 reference

GAD65 is essential for synthesis of GABA destined for tonic inhibition regulating epileptiform activity

21 January 2018

1 reference

Knockout of GAD65 has major impact on synaptic GABA synthesized from astrocyte-derived glutamine

21 January 2018

1 reference

Modulation of memory by insulin and glucose: neuropsychological observations in Alzheimer's disease

21 January 2018

1 reference

Functional consequences of locus coeruleus degeneration in Alzheimer's disease

21 January 2018

1 reference

Induction of serine racemase expression and D-serine release from microglia by amyloid beta-peptide

21 January 2018

1 reference

β-amyloid peptide binds and regulates ectopic ATP synthase α-chain on neural surface

21 January 2018

1 reference

Molecular and cellular mechanisms for Alzheimer's disease: understanding APP metabolism

21 January 2018

1 reference

GABA and Glutamate Transporters in Brain

21 January 2018

1 reference

Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease

21 January 2018

1 reference

The neuropathology of aminergic nuclei in Alzheimer's disease.

21 January 2018

1 reference

Amyloid precursor protein and amyloid β-peptide bind to ATP synthase and regulate its activity at the surface of neural cells

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/JNC.13107

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2 September 2017

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