(Q38411818)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

title

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

0 references

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Jerome Mertens

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Emily Hatch

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

José Tiago Gonçalves

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

17

Fred H Gage

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

2

Apuã C M Paquola

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

14

Jürgen Winkler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

author name string

Manching Ku

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Lena Böhnke

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Shauheen Ladjevardi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Sean McGrath

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Benjamin Campbell

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Hyungjun Lee

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Joseph R Herdy

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Tomohisa Toda

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Yongsung Kim

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Martin W Hetzer

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

language of work or name

English

0 references

publication date

8 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

page(s)

705-718

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

Epigenetic rejuvenation of mesenchymal stromal cells derived from induced pluripotent stem cells

26 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Epigenome rejuvenation: HP1β mobility as a measure of pluripotent and senescent chromatin ground states

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

HIV-1 Vpr-a still "enigmatic multitasker".

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

REST and stress resistance in ageing and Alzheimer's disease

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Human iPSC-based modeling of late-onset disease via progerin-induced aging

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Injury-induced HDAC5 nuclear export is essential for axon regeneration.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Identification of long-lived proteins reveals exceptional stability of essential cellular structures

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

The origin of aging: imperfectness-driven non-random damage defines the aging process and control of lifespan

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Age-specific signatures of glioblastoma at the genomic, genetic, and epigenetic levels

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Protein homeostasis: live long, won't prosper

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Small molecules enable highly efficient neuronal conversion of human fibroblasts

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Extremely long-lived nuclear pore proteins in the rat brain

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Induction of human neuronal cells by defined transcription factors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Mitochondrial rejuvenation after induced pluripotency

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Identification of RANBP16 and RANBP17 as novel interaction partners for the bHLH transcription factor E12.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Direct conversion of fibroblasts to functional neurons by defined factors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

The role of nuclear pores in gene regulation, development and disease

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Association of FOXO3A variation with human longevity confirmed in German centenarians

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

FOXO3A genotype is strongly associated with human longevity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Genome-scale DNA methylation maps of pluripotent and differentiated cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Motif module map reveals enforcement of aging by continual NF-kappaB activity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Lamin A-dependent nuclear defects in human aging

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Neural plasticity in the ageing brain

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Aging and gene expression in the primate brain

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Gene regulation and DNA damage in the ageing human brain

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Identification of a novel putative Ran-binding protein and its close homologue

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Progeria: a paradigm for translational medicine.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Embryonic stem cell-based modeling of tau pathology in human neurons.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Hutchinson-Gilford progeria syndrome: review of the phenotype.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

Axoplasmic importins enable retrograde injury signaling in lesioned nerve.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5929130

31 August 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/26456686

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Altered calcium uptake in cultured skin fibroblasts from patients with Alzheimer's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26456686

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STEM.2015.09.001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PubMed publication ID

26456686

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26456686%20AND%20SRC:MED&resulttype=core&format=json