(Q38413705)

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ELYPSE-7: a randomized placebo-controlled phase IIa trial with CYT107 exploring the restoration of CD4+ lymphocyte count in lymphopenic metastatic breast cancer patients.

scientific article published on 07 April 2015

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25851629%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

ELYPSE-7: a randomized placebo-controlled phase IIa trial with CYT107 exploring the restoration of CD4+ lymphocyte count in lymphopenic metastatic breast cancer patients (English)

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4 March 2020

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metastatic breast cancer

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based on heuristic

inferred from title

23

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4 March 2020

Olivier Trédan

1

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4 March 2020

Christine Ménétrier-Caux

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4 March 2020

Christophe Caux

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4 March 2020

Isabelle Ray-Coquard

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I Ray-Coquard

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4 March 2020

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G Garin

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4 March 2020

C Cropet

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4 March 2020

E Verronèse

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4 March 2020

T Bachelot

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P Rebattu

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P E Heudel

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4 March 2020

P Cassier

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4 March 2020

S Chabaud

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4 March 2020

T Croughs

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4 March 2020

P Dupont

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4 March 2020

A C Cadore

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4 March 2020

G Clapisson

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4 March 2020

A Delgado

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4 March 2020

C Bardin-dit-Courageot

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4 March 2020

C Rigal

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4 March 2020

A N'Kodia

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4 March 2020

L Gilles-Afchain

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4 March 2020

M Morre

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4 March 2020

D Pérol

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4 March 2020

publication date

7 April 2015

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4 March 2020

Annals of Oncology

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4 March 2020

26

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4 March 2020

7

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4 March 2020

1353-1362

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4 March 2020

Early lymphopenia after cytotoxic chemotherapy as a risk factor for febrile neutropenia

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Pre-treatment lymphopenia as a prognostic biomarker in colorectal cancer patients receiving chemotherapy

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Lymphopenia is an independent predictor of inferior outcome in clear cell renal carcinoma

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

CD4 lymphopenia as a risk factor for febrile neutropenia and early death after cytotoxic chemotherapy in adult patients with cancer.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Baseline and early lymphopenia predict for the risk of febrile neutropenia after chemotherapy

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Lymphopenia combined with low TCR diversity (divpenia) predicts poor overall survival in metastatic breast cancer patients.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

CD4 lymphopenia to identify end-of-life metastatic cancer patients

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Identification of patients at risk for early death after conventional chemotherapy in solid tumours and lymphomas

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

A potential role for interleukin-7 in T-cell homeostasis

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Recombinant IL-7 enhances the potency of GM-CSF-secreting tumor cell immunotherapy

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Interleukin-7 and immune reconstitution in cancer patients: a new paradigm for dramatically increasing overall survival

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Chemo-immunotherapy with oxaliplatin and interleukin-7 inhibits colon cancer metastasis in mice

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Interleukin-7 Gene-Modified Dendritic Cells Reduce Pulmonary Tumor Burden in Spontaneous Murine Bronchoalveolar Cell Carcinoma

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Injection of glycosylated recombinant simian IL-7 provokes rapid and massive T-cell homing in rhesus macaques.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Effects of recombinant human interleukin 7 on T-cell recovery and thymic output in HIV-infected patients receiving antiretroviral therapy: results of a phase I/IIa randomized, placebo-controlled, multicenter study

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Phase I study of recombinant human interleukin-7 administration in subjects with refractory malignancy

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Factorial design considerations.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Recombinant human interleukin-7 (CYT107) promotes T-cell recovery after allogeneic stem cell transplantation

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Harnessing the biology of IL-7 for therapeutic application

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Interleukin 7 induces cytokine secretion and tumoricidal activity by human peripheral blood monocytes

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Targeting regulatory T cells

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

ICOS-ligand expression on plasmacytoid dendritic cells supports breast cancer progression by promoting the accumulation of immunosuppressive CD4+ T cells.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

IL-7 modulates in vitro and in vivo human memory T regulatory cell functions through the CD39/ATP axis.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Quantifying and predicting the effect of exogenous interleukin-7 on CD4+ T cells in HIV-1 infection

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Endothelial nitric oxide synthase is a key mediator of interleukin-2-induced hypotension and vascular leak syndrome.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Patients with metastatic breast cancer leading to CD4+ T cell lymphopaenia have poor outcome

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Impaired IFN- Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDV173

21 January 2018

Identifiers

10.1093/ANNONC/MDV173

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25851629%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25851629%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

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