(Q38449526)

3 September 2017

1 reference

title

Recent advances of microRNA-based molecular diagnostics to reduce false-positive lung cancer imaging (English)

1 reference

3 September 2017

1 reference

1 reference

Carla Verri

4

0 references

Stefano Sestini

Stefano Sestini

2

0 references

Mattia Boeri

Mattia Boeri

1

0 references

Orazio Fortunato

Orazio Fortunato

3

0 references

Gabriella Sozzi

Gabriella Sozzi

7

0 references

Ugo Pastorino

Ugo Pastorino

6

0 references

Paola Suatoni

5

Paola Suatoni

1 reference

3 September 2017

publication date

30 April 2015

1 reference

Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare

3 September 2017

published in

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3 September 2017

volume

15

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3 September 2017

issue

6

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3 September 2017

page(s)

801-813

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Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012

3 September 2017

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21 January 2018

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21 January 2018

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Peripheral lung cancer: screening and detection with low-dose spiral CT versus radiography

21 January 2018

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Mass screening for lung cancer with mobile spiral computed tomography scanner

21 January 2018

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Early Lung Cancer Action Project: overall design and findings from baseline screening

21 January 2018

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Survival of patients with stage I lung cancer detected on CT screening

21 January 2018

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Final results of the Lung Screening Study, a randomized feasibility study of spiral CT versus chest X-ray screening for lung cancer

21 January 2018

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Selection criteria for lung-cancer screening

21 January 2018

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Management of lung nodules detected by volume CT scanning.

21 January 2018

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CT screening for lung cancer brings forward early disease. The randomised Danish Lung Cancer Screening Trial: status after five annual screening rounds with low-dose CT.

21 January 2018

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Annual or biennial CT screening versus observation in heavy smokers: 5-year results of the MILD trial.

21 January 2018

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Randomized study on early detection of lung cancer with MSCT in Germany: study design and results of the first screening round.

21 January 2018

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Four-year results of low-dose CT screening and nodule management in the ITALUNG trial

21 January 2018

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A randomized study of lung cancer screening with spiral computed tomography: three-year results from the DANTE trial.

21 January 2018

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Baseline results of the Depiscan study: a French randomized pilot trial of lung cancer screening comparing low dose CT scan (LDCT) and chest X-ray (CXR).

21 January 2018

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CT screening for lung cancer: five-year prospective experience

21 January 2018

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Early lung-cancer detection with spiral CT and positron emission tomography in heavy smokers: 2-year results

21 January 2018

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Screening for early lung cancer with low-dose spiral CT: prevalence in 817 asymptomatic smokers.

21 January 2018

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Computed tomography screening and lung cancer outcomes

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Overdiagnosis in low-dose computed tomography screening for lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Cost-effectiveness of computed tomography screening for lung cancer in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Lung cancer: CT screening for lung cancer--do we have an answer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Causes and consequences of microRNA dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MiR-155-mediated loss of C/EBPβ shifts the TGF-β response from growth inhibition to epithelial-mesenchymal transition, invasion and metastasis in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

miR-661 downregulates both Mdm2 and Mdm4 to activate p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Role of microRNAs in lung cancer: microRNA signatures in cancer prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MicroRNAs in body fluids--the mix of hormones and biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Clinical relevance of circulating cell-free microRNAs in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Characterization of extracellular circulating microRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Cell-to-cell miRNA transfer: from body homeostasis to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Secretory mechanisms and intercellular transfer of microRNAs in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MicroRNAs and lung cancer: from markers to targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Mir-660 is downregulated in lung cancer patients and its replacement inhibits lung tumorigenesis by targeting MDM2-p53 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

miRNA detection methods and clinical implications in lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Real-time quantification of microRNAs by stem-loop RT-PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Expression profiling of microRNA using real-time quantitative PCR, how to use it and what is available

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Circulating microRNAs as stable blood-based markers for cancer detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Assessing sample and miRNA profile quality in serum and plasma or other biofluids

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Method for microRNA isolation from clinical serum samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Microarray oligonucleotide probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Direct and sensitive miRNA profiling from low-input total RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Robust global microRNA expression profiling using next-generation sequencing technologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Circulating micro-RNA expression profiles in early stage nonsmall cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Plasma microRNAs as potential biomarkers for non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Benefits and harms of CT screening for lung cancer: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

A serum circulating miRNA diagnostic test to identify asymptomatic high-risk individuals with early stage lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Clinical utility of a plasma-based miRNA signature classifier within computed tomography lung cancer screening: a correlative MILD trial study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Lung cancer screening with low-dose computed tomography: a non-invasive diagnostic protocol for baseline lung nodules

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

miR-Test: A Blood Test for Lung Cancer Early Detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Diagnosis of lung cancer in individuals with solitary pulmonary nodules by plasma microRNA biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Analysis of MicroRNAs in sputum to improve computed tomography for lung cancer diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Sputum microRNA biomarkers for identifying lung cancer in indeterminate solitary pulmonary nodules

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

microRNAs derived from circulating exosomes as noninvasive biomarkers for screening and diagnosing lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Assessment of circulating microRNAs in plasma of lung cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Therapeutic use of microRNAs in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Knockdown of microRNA-21 inhibits proliferation and increases cell death by targeting programmed cell death 4 (PDCD4) in pancreatic ductal adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MicroRNA-21 targets tumor suppressor genes in invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MicroRNA-17~92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MiR-155 inhibits the sensitivity of lung cancer cells to cisplatin via negative regulation of Apaf-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Knockdown of ZEB1, a master epithelial-to-mesenchymal transition (EMT) gene, suppresses anchorage-independent cell growth of lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

miR-141 and miR-200c as markers of overall survival in early stage non-small cell lung cancer adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

RAS is regulated by the let-7 microRNA family

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

The tumor suppressor microRNA let-7 represses the HMGA2 oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

let-7 regulates Dicer expression and constitutes a negative feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

The let-7 microRNA represses cell proliferation pathways in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Identification of a tumor-suppressive human-specific microRNA within the FHIT tumor-suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Downregulation of miR-486-5p contributes to tumor progression and metastasis by targeting protumorigenic ARHGAP5 in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

Pim-1 kinase is a target of miR-486-5p and eukaryotic translation initiation factor 4E, and plays a critical role in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

miR-126 enhances the sensitivity of non-small cell lung cancer cells to anticancer agents by targeting vascular endothelial growth factor A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

miR-126 inhibits non-small cell lung cancer cells proliferation by targeting EGFL7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

European randomized lung cancer screening trials: Post NLST

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.2015.1041377

10.1586/14737159.2015.1041377

21 January 2018

Identifiers

DOI

1 reference

3 September 2017

1 reference