(Q38467344)

3 September 2017

Discovery of Potent and Selective Urea-Based ROCK Inhibitors and Their Effects on Intraocular Pressure in Rats (English)

1 reference

3 September 2017

9

Stephan Schürer

1 reference

3 September 2017

Yan Yin

1

1 reference

3 September 2017

Michael D Cameron

2

1 reference

3 September 2017

Li Lin

3

1 reference

3 September 2017

Susan Khan

4

1 reference

3 September 2017

Thomas Schröter

5

1 reference

3 September 2017

Wayne Grant

6

1 reference

3 September 2017

Jennifer Pocas

7

1 reference

3 September 2017

Yen Ting Chen

8

1 reference

3 September 2017

Alok Pachori

10

1 reference

3 September 2017

Philip LoGrasso

11

1 reference

3 September 2017

Yangbo Feng

12

1 reference

3 September 2017

5 April 2010

1 reference

ACS Medicinal Chemistry Letters

3 September 2017

1 reference

3 September 2017

1

1 reference

3 September 2017

4

1 reference

3 September 2017

175-179

1 reference

Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors.

3 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

Detection of myosin light chain phosphorylation--a cell-based assay for screening Rho-kinase inhibitors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

Comparison of miniaturized time-resolved fluorescence resonance energy transfer and enzyme-coupled luciferase high-throughput screening assays to discover inhibitors of Rho-kinase II (ROCK-II).

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

Molecular design for enhancement of ocular penetration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

Rodent models for glaucoma retinopathy and optic neuropathy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

The number of people with glaucoma worldwide in 2010 and 2020

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

Dose response and duration of action of dorzolamide, a topical carbonic anhydrase inhibitor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

The mechanism of timolol in lowering intraocular pressure. In the normal eye.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

The effect of the H-1152P, a potent Rho-associated coiled coil-formed protein kinase inhibitor, in rabbit normal and ocular hypertensive eyes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

Contribution of ROCK in contraction of trabecular meshwork: proposed mechanism for regulating aqueous outflow in monkey and human eyes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

Acute effects of glaucoma medications on rat intraocular pressure

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007833

Effects of brimonidine on aqueous humor dynamics in human eyes

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900192

12 December 2020

inferred from PubMed ID database lookup

Effects of topical administration of y-39983, a selective rho-associated protein kinase inhibitor, on ocular tissues in rabbits and monkeys

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900192

12 December 2020

inferred from PubMed ID database lookup

Intraocular pressure-lowering effects and safety of topical administration of a selective ROCK inhibitor, SNJ-1656, in healthy volunteers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900192

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1021/ML1000382

1 reference

release_7wg3nixotbgprpj3uofnjtysya

3 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7wg3nixotbgprpj3uofnjtysya

24 November 2022

mapped directly with Wikidata item

1 reference

3 September 2017

PubMed publication ID

24900192

1 reference