(Q38474958)

English

Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

scientific article published on 03 March 2005

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scholarly article

1 reference

Europe PubMed Central

3 September 2017

Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (English)

1 reference

Europe PubMed Central

3 September 2017

Escherichia coli

1 reference

based on heuristic

inferred from title

Vern L. Schramm

8

object named as

Vern L Schramm

1 reference

Europe PubMed Central

3 September 2017

2

object named as

Vipender Singh

1 reference

Europe PubMed Central

3 September 2017

author name string

Jeffrey E Lee

1

1 reference

Europe PubMed Central

3 September 2017

Gary B Evans

3

1 reference

Europe PubMed Central

3 September 2017

Peter C Tyler

4

1 reference

Europe PubMed Central

3 September 2017

Richard H Furneaux

5

1 reference

Europe PubMed Central

3 September 2017

Kenneth A Cornell

6

1 reference

Europe PubMed Central

3 September 2017

Michael K Riscoe

7

1 reference

Europe PubMed Central

3 September 2017

P Lynne Howell

9

1 reference

Europe PubMed Central

3 September 2017

language of work or name

0 references

publication date

3 March 2005

1 reference

Europe PubMed Central

3 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

3 September 2017

280

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Europe PubMed Central

3 September 2017

18274-18282

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Europe PubMed Central

3 September 2017

18

1 reference

Europe PubMed Central

3 September 2017

Inhibition of the synthesis of polyamines and macromolecules by 5'-methylthioadenosine and 5'-alkylthiotubercidins in BHK21 cells

1 reference

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Methylthioadenosine, a potent inhibitor of spermine synthase from bovine brain

1 reference

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21 January 2018

Methionine recycling pathways and antimalarial drug design

1 reference

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Structural identification of a bacterial quorum-sensing signal containing boron

1 reference

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The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule

1 reference

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21 January 2018

Structure of E. coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase reveals similarity to the purine nucleoside phosphorylases

1 reference

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21 January 2018

Structure of Escherichia coli 5'-methylthioadenosine/ S-adenosylhomocysteine nucleosidase inhibitor complexes provide insight into the conformational changes required for substrate binding and catalysis

1 reference

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21 January 2018

Structural comparison of MTA phosphorylase and MTA/AdoHcy nucleosidase explains substrate preferences and identifies regions exploitable for inhibitor design

1 reference

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21 January 2018

Structural analyses reveal two distinct families of nucleoside phosphorylases

1 reference

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21 January 2018

The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis

1 reference

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21 January 2018

Purine nucleoside phosphorylase. 2. Catalytic mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Purine nucleoside phosphorylase. Catalytic mechanism and transition-state analysis of the arsenolysis reaction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Transition state analysis for human and Plasmodium falciparum purine nucleoside phosphorylases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

VMD: visual molecular dynamics

1 reference

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21 January 2018

Purine nucleoside phosphorylase: a target for drug design

1 reference

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21 January 2018

One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase

1 reference

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21 January 2018

8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Femtomolar transition state analogue inhibitors of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Expression, purification, crystallization and preliminary X-ray analysis of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

The finer things in X-ray diffraction data collection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Characterization of recombinant Eschericha coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase: analysis of enzymatic activity and substrate specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

S-adenosylmethionine conformations in solution and in protein complexes: conformational influences of the sulfonium group.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Hydrogen bonding and biological specificity analysed by protein engineering

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Low-barrier hydrogen bonds and enzymatic catalysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414471200

21 January 2018

Low-barrier hydrogen bonds and enzymic catalysis

1 reference

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A low-barrier hydrogen bond in the catalytic triad of serine proteases

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21 January 2018

Understanding the rates of certain enzyme-catalyzed reactions: proton abstraction from carbon acids, acyl-transfer reactions, and displacement reactions of phosphodiesters

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21 January 2018

Aromatic-aromatic interaction: a mechanism of protein structure stabilization

1 reference

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Swiss-PDB Viewer (Deep View).

1 reference

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Raster3D: photorealistic molecular graphics

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21 January 2018

Iminoribitol Transition State Analogue Inhibitors of Protozoan Nucleoside Hydrolases†

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21 January 2018

Identifiers

10.1074/JBC.M414471200

1 reference

Europe PubMed Central

3 September 2017

1 reference

Europe PubMed Central

3 September 2017

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