(Q38506744)

3 September 2017

title

Therapeutic implications of down-regulation of cyclophilin D in bipolar disorder (English)

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3 September 2017

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2

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3 September 2017

7

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3 September 2017

Mie Kubota

1

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3 September 2017

Kazuya Iwamoto

3

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3 September 2017

Atsuko Komori

4

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3 September 2017

Mizuho Ishiwata

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3 September 2017

Taeko Miyauchi

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3 September 2017

publication date

15 April 2010

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The International Journal of Neuropsychopharmacology

3 September 2017

published in

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3 September 2017

volume

13

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3 September 2017

issue

10

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3 September 2017

page(s)

1355-1368

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The role of cyclophilin D in learning and memory

3 September 2017

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Oxidative stress is not an obligate mediator of disease provoked by mitochondrial DNA mutations

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Cardiac disease due to random mitochondrial DNA mutations is prevented by cyclosporin A.

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7 January 2021

Mitochondrial DNA mutations cause resistance to opening of the permeability transition pore

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7 January 2021

Cell-type specific regulation of calreticulin and Bcl-2 expression by mood stabilizer drugs

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7 January 2021

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

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7 January 2021

The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

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Attenuation of acute mitochondrial dysfunction after traumatic brain injury in mice by NIM811, a non-immunosuppressive cyclosporin A analog

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Enhancement of anxiety, facilitation of avoidance behavior, and occurrence of adult-onset obesity in mice lacking mitochondrial cyclophilin D

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Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior

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7 January 2021

Presynaptic mitochondrial calcium sequestration influences transmission at mammalian central synapses.

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7 January 2021

Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D.

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Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions

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7 January 2021

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

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7 January 2021

The mitochondrial phosphate carrier interacts with cyclophilin D and may play a key role in the permeability transition

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7 January 2021

Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism

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Abnormal Ca2+ dynamics in transgenic mice with neuron-specific mitochondrial DNA defects.

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7 January 2021

Protective effects of NIM811 in transient focal cerebral ischemia suggest involvement of the mitochondrial permeability transition.

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7 January 2021

Mitochondrial DNA mutations activate programmed cell survival in the mouse heart

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7 January 2021

Increased expression of splicing factor SRp20 mRNA in bipolar disorder patients

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7 January 2021

Long-lasting effects of stress on glucocorticoid receptor gene expression in the rat brain

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7 January 2021

Interplay between Na+/Ca2+ exchangers and mitochondria in Ca2+ clearance at the calyx of Held.

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7 January 2021

Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811.

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7 January 2021

Reduction of brain phosphocreatine in bipolar II disorder detected by phosphorus-31 magnetic resonance spectroscopy

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7 January 2021

Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain

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7 January 2021

Alterations in brain phosphorous metabolism in bipolar disorder detected by in vivo 31P and 7Li magnetic resonance spectroscopy.

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7 January 2021

Multiple deletions of mitochondrial DNA in several tissues of a patient with severe retarded depression and familial progressive external ophthalmoplegia

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7 January 2021

Mitochondrial dysfunction in bipolar disorder

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https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Dose-response curve and optimal dosing regimen of cyclosporin A after traumatic brain injury in rats

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7 January 2021

Molecular neurobiology of bipolar disorder: a disease of 'mood-stabilizing neurons'?

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7 January 2021

Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research

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7 January 2021

Mitochondrial dysfunction as the molecular basis of bipolar disorder: therapeutic implications.

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7 January 2021

Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux

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https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder

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https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

In vivo evidence for ATP-dependent and P-glycoprotein-mediated transport of cyclosporin A at the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: a role of histone deacetylase inhibition

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Elevated cerebrospinal fluid lactate concentrations in patients with bipolar disorder and schizophrenia: implications for the mitochondrial dysfunction hypothesis

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Post-treatment with the cyclosporin derivative, NIM811, reduced indices of cell death and increased the volume of spared tissue in the acute period following spinal cord contusion

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Functional analysis of the promoter of the mitochondrial phosphate carrier human gene: identification of activator and repressor elements and their transcription factors

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https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Induction of immunosuppression by microemulsion cyclosporine in liver transplantation.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

The ability of atypical antipsychotic drugs vs. haloperidol to protect PC12 cells against MPP+‐induced apoptosis

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Regulatory changes in neuroendocrine stress-integrative circuitry produced by a variable stress paradigm

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

The nonimmunosuppressive cyclosporin analogs NIM811 and UNIL025 display nanomolar potencies on permeability transition in brain-derived mitochondria.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Genome-wide expression analysis detects eight genes with robust alterations specific to bipolar I disorder: relevance to neuronal network perturbation

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Alternatively Spliced Genes as Biomarkers for Schizophrenia, Bipolar Disorder and Psychosis: A Blood-Based Spliceome-Profiling Exploratory Study

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

High cyclophilin D content of synaptic mitochondria results in increased vulnerability to permeability transition.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1017%2FS1461145710000362

7 January 2021

10.1017/S1461145710000362

Identifiers

DOI

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3 September 2017

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