(Q45236966)

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Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2.

scientific article published in January 2005

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scholarly article

1 reference

Europe PubMed Central

11 December 2017

Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2. (English)

1 reference

Europe PubMed Central

11 December 2017

author name string

Hiroi T

1

1 reference

Europe PubMed Central

11 December 2017

Wei H

2

1 reference

Europe PubMed Central

11 December 2017

Hough C

3

1 reference

Europe PubMed Central

11 December 2017

Leeds P

4

1 reference

Europe PubMed Central

11 December 2017

Chuang DM

5

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Europe PubMed Central

11 December 2017

language of work or name

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publication date

1 January 2005

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Europe PubMed Central

11 December 2017

The Pharmacogenomics Journal

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Europe PubMed Central

11 December 2017

5

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Europe PubMed Central

11 December 2017

2

1 reference

Europe PubMed Central

11 December 2017

102-111

1 reference

Europe PubMed Central

11 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.tpj.6500296

0 references

Coupling endoplasmic reticulum stress to the cell death program

1 reference

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21 January 2018

The mammalian endoplasmic reticulum as a sensor for cellular stress

1 reference

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21 January 2018

A trip to the ER: coping with stress

1 reference

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21 January 2018

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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21 January 2018

Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells

1 reference

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21 January 2018

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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21 January 2018

BH-3-only BIK functions at the endoplasmic reticulum to stimulate cytochrome c release from mitochondria

1 reference

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21 January 2018

Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders

1 reference

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21 January 2018

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

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21 January 2018

Endoplasmic reticulum: a primary target in various acute disorders and degenerative diseases of the brain

1 reference

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21 January 2018

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx

1 reference

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21 January 2018

Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation.

1 reference

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21 January 2018

beta-amyloid peptide-induced death of PC 12 cells and cerebellar granule cell neurons is inhibited by long-term lithium treatment

1 reference

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21 January 2018

Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium

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21 January 2018

Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons

1 reference

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21 January 2018

Evaluation of neuroprotection by lithium and valproic acid against ouabain-induced cell damage

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21 January 2018

Lithium induces apoptosis in immature cerebellar granule cells but promotes survival of mature neurons.

1 reference

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21 January 2018

Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration.

1 reference

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21 January 2018

Long-term lithium treatment prevents neurotoxic effects of beta-bungarotoxin in primary cultured neurons.

1 reference

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21 January 2018

Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats

1 reference

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21 January 2018

Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model

1 reference

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21 January 2018

Chronic treatment with a low dose of lithium protects the brain against ischemic injury by reducing apoptotic death

1 reference

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21 January 2018

Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington's disease

1 reference

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21 January 2018

Short-term lithium treatment promotes neuronal survival and proliferation in rat striatum infused with quinolinic acid, an excitotoxic model of Huntington's disease

1 reference

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21 January 2018

Effects of chronic lithium treatment on ornithine decarboxylase induction and excitotoxic neuropathology in the rat.

1 reference

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21 January 2018

Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity.

1 reference

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21 January 2018

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

1 reference

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21 January 2018

Chronic lithium treatment antagonizes glutamate-induced decrease of phosphorylated CREB in neurons via reducing protein phosphatase 1 and increasing MEK activities

1 reference

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21 January 2018

A molecular mechanism for the effect of lithium on development

1 reference

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21 January 2018

Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium

1 reference

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21 January 2018

Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3.

1 reference

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21 January 2018

Lithium-induced inhibition of Src tyrosine kinase in rat cerebral cortical neurons: a role in neuroprotection against N-methyl-D-aspartate receptor-mediated excitotoxicity

1 reference

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21 January 2018

Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation

1 reference

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21 January 2018

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase

1 reference

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21 January 2018

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

1 reference

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21 January 2018

The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis.

1 reference

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21 January 2018

Induction of Bip mRNA upon programmed cell death of differentiated PC12 cells as well as rat sympathetic neurons

1 reference

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21 January 2018

Involvement of c-Fos in signaling grp78 induction following ER calcium release.

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21 January 2018

Lithium augments fos protoonocogene expression in PC12 pheochromocytoma cells: implications for therapeutic action of lithium.

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21 January 2018

Long-term biphasic effects of lithium treatment on phospholipase C-coupled M3-muscarinic acetylcholine receptors in cultured cerebellar granule cells.

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21 January 2018

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes

1 reference

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21 January 2018

Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2

1 reference

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21 January 2018

Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

1 reference

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21 January 2018

The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

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Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

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Stress protein GRP78 prevents apoptosis induced by calcium ionophore, ionomycin, but not by glycosylation inhibitor, tunicamycin, in human prostate cancer cells

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Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78

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Lithium inhibits Abeta-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation

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Regulation of c-Jun N-terminal kinase, p38 kinase and AP-1 DNA binding in cultured brain neurons: roles in glutamate excitotoxicity and lithium neuroprotection

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Mitogen-activated protein kinase cascades as regulators of stress responses

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The pathophysiology of mitochondrial cell death

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Increased expression of endoplasmic reticulum stress proteins following chronic valproate treatment of rat C6 glioma cells.

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Chronic valproate treatment increases expression of endoplasmic reticulum stress proteins in the rat cerebral cortex and hippocampus

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21 January 2018

Increase in AP-1 transcription factor DNA binding activity by valproic acid.

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Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers

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Neuroimaging and neuropathological studies of depression: implications for the cognitive-emotional features of mood disorders

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The role of the extracellular signal-regulated kinase signaling pathway in mood modulation.

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Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain.

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Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction.

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10.1038/SJ.TPJ.6500296

1 reference

Europe PubMed Central

11 December 2017

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1 reference

Europe PubMed Central

11 December 2017

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