(Q44264548)

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Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity.

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16 December 2019

Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity (English)

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16 December 2019

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Ryota Hashimoto

1

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16 December 2019

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Nobuyuki Takei

2

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16 December 2019

Kazuhiro Shimazu

3

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16 December 2019

Lori Christ

4

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16 December 2019

Bai Lu

5

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16 December 2019

publication date

1 December 2002

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16 December 2019

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7

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Neuropharmacology

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16 December 2019

43

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16 December 2019

7

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16 December 2019

1173-1179

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16 December 2019

Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration.

1 reference

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Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation.

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Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration

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Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium

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Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

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7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

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7 January 2021

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

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7 January 2021

The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

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7 January 2021

Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

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Neuroprotective effects of lithium in cultured cells and animal models of diseases.

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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7 January 2021

CREB is a regulatory target for the protein kinase Akt/PKB

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7 January 2021

Neural plasticity to stress and antidepressant treatment

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7 January 2021

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

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7 January 2021

Calcium regulation of the brain-derived neurotrophic factor gene

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7 January 2021

Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain

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7 January 2021

Site-specific phosphorylation of neurofilament-L is mediated by calcium/calmodulin-dependent protein kinase II in the apical dendrites during long-term potentiation

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7 January 2021

Visual stimulation-induced phosphorylation of neurofilament-L in the visual cortex of dark-reared rats

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7 January 2021

Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation.

1 reference

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7 January 2021

Neurotrophins: roles in neuronal development and function

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Lithium treatment in ovo: effects on embryonic heart rate, natural death of ciliary ganglion neurons, and brain expression of a highly conserved chicken homolog of human MTG8/ETO.

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7 January 2021

Lithium delays the radiation-induced apoptotic process in external granule cells of mouse cerebellum

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7 January 2021

Pulse exposure of cultured rat neurons to aluminum-maltol affected the axonal transport system.

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7 January 2021

Chronic lithium treatment antagonizes glutamate-induced decrease of phosphorylated CREB in neurons via reducing protein phosphatase 1 and increasing MEK activities

1 reference

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7 January 2021

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor

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7 January 2021

Lithium attenuates p53 levels in human neuroblastoma SH-SY5Y cells

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7 January 2021

Neurotrophins and synaptic plasticity

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7 January 2021

Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms

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7 January 2021

BDNF protein measured by a novel enzyme immunoassay in normal brain and after seizure: partial disagreement with mRNA levels

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7 January 2021

Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments.

1 reference

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7 January 2021

Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats

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7 January 2021

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx

1 reference

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7 January 2021

Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain.

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7 January 2021

Trk receptors: mediators of neurotrophin action

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Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice.

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Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons

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Phosphoinositide 3-OH kinase (PI3K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis

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7 January 2021

Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.

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7 January 2021

Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus.

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Nerve growth factor signaling, neuroprotection, and neural repair

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Brain-derived neurotrophic factor induces rapid and transient release of glutamate through the non-exocytotic pathway from cortical neurons.

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BDNF and NT-3 but not CNTF counteract the Ca2+ ionophore-induced apoptosis of cultured cortical neurons: involvement of dual pathways.

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beta-amyloid peptide-induced death of PC 12 cells and cerebellar granule cell neurons is inhibited by long-term lithium treatment

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Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington's disease

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Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

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Identifiers

10.1016/S0028-3908(02)00217-4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12504924%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12504924%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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