(Q38537381)

3 September 2017

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title

The hitchhiker's guide to PGC-1α isoform structure and biological functions (English)

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3 September 2017

2

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Jorge L Ruas

series ordinal

3

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author name string

Vicente Martínez-Redondo

series ordinal

1

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3 September 2017

publication date

25 June 2015

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3 September 2017

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3 September 2017

volume

58

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3 September 2017

issue

9

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3 September 2017

page(s)

1969-1977

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A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

3 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Alternative promoters influence alternative splicing at the genomic level

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Alternative isoform regulation in human tissue transcriptomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Metabolic control through the PGC-1 family of transcription coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Linking DNA methylation and histone modification: patterns and paradigms

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Acute exercise remodels promoter methylation in human skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Weight loss after gastric bypass surgery in human obesity remodels promoter methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

RNF34 is a cold-regulated E3 ubiquitin ligase for PGC-1α and modulates brown fat cell metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Isoform-specific increases in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to beta2-adrenergic receptor activation and exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Identification and characterization of an alternative promoter of the human PGC-1alpha gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Alternative splice variant PGC-1α-b is strongly induced by exercise in human skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Resistance exercise training modulates acute gene expression during human skeletal muscle hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Skeletal muscle-specific expression of PGC-1α-b, an exercise-responsive isoform, increases exercise capacity and peak oxygen uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Differential regulation of the expressions of the PGC-1α splice variants, lipins, and PPARα in heart compared to liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Characterization of novel peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) isoform in human liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

The gene coding for PGC-1alpha modifies age at onset in Huntington's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

NT-PGC-1α protein is sufficient to link β3-adrenergic receptor activation to transcriptional and physiological components of adaptive thermogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Twist-1 is a PPARdelta-inducible, negative-feedback regulator of PGC-1alpha in brown fat metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by truncated peroxisome proliferator-activated receptor γ coactivator (PGC)-1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1α-Fndc5 pathway in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Effect of exercise intensity and AICAR on isoform-specific expressions of murine skeletal muscle PGC-1α mRNA: a role of β₂-adrenergic receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

β-Adrenergic stimulation does not activate p38 MAP kinase or induce PGC-1α in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

The truncated splice variants, NT-PGC-1α and PGC-1α4, increase with both endurance and resistance exercise in human skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Truncated splice variant PGC-1α4 is not associated with exercise-induced human muscle hypertrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

The transcriptional coactivator PGC-1α is dispensable for chronic overload-induced skeletal muscle hypertrophy and metabolic remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-015-3671-Z

Effect of exercise intensity on isoform-specific expressions of NT-PGC-1 α mRNA in mouse skeletal muscle

21 January 2018

1 reference

12 December 2020

GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha

1 reference

12 December 2020

Regulation of mitochondrial biogenesis in skeletal muscle by CaMK

1 reference

12 December 2020

Transcriptional Activity of PGC-1α and NT-PGC-1α Is Differentially Regulated by Twist-1 in Brown Fat Metabolism

1 reference

12 December 2020

Role of leptin in peroxisome proliferator-activated receptor gamma coactivator-1 expression

1 reference

12 December 2020

Seven days of muscle re-loading and voluntary wheel running following hindlimb suspension in mice restores running performance, muscle morphology and metrics of fatigue but not muscle strength

1 reference

12 December 2020

10.1007/S00125-015-3671-Z

Identifiers

DOI

1 reference

Dimensions Publication ID

3 September 2017

1023431715

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1 reference