(Q38547024)

4 September 2017

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title

Releasing 'brakes' to nerve regeneration: intrinsic molecular targets (English)

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4 September 2017

Anand Krishnan

1

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4 September 2017

Arul Duraikannu

series ordinal

2

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4 September 2017

Douglas W Zochodne

series ordinal

3

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4 September 2017

language of work or name

English

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publication date

14 July 2015

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European Journal of Neuroscience

4 September 2017

published in

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4 September 2017

volume

43

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4 September 2017

issue

3

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4 September 2017

page(s)

297-308

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Rb/E2F regulates expression of neogenin during neuronal migration

4 September 2017

cites work

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Activation of casein kinase II and inhibition of phosphatase and tensin homologue deleted on chromosome 10 phosphatase by nerve growth factor/p75NTR inhibit glycogen synthase kinase-3beta and stimulate axonal growth

21 January 2018

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ErbB2 signaling in Schwann cells is mostly dispensable for maintenance of myelinated peripheral nerves and proliferation of adult Schwann cells after injury.

21 January 2018

1 reference

Are p27 and p21 cytoplasmic oncoproteins?

21 January 2018

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Dynamic changes of Jab1 and p27kip1 expression in injured rat sciatic nerve.

21 January 2018

1 reference

Peripheral axon regrowth: new molecular approaches

21 January 2018

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PTEN inhibition to facilitate intrinsic regenerative outgrowth of adult peripheral axons.

21 January 2018

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Disruption of E3 ligase NEDD4 in peripheral neurons interrupts axon outgrowth: Linkage to PTEN.

21 January 2018

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Enhancing adult nerve regeneration through the knockdown of retinoblastoma protein

21 January 2018

1 reference

New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?

21 January 2018

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Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination

21 January 2018

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p53 post-translational modification: deregulated in tumorigenesis

21 January 2018

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The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration

21 January 2018

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Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth.

21 January 2018

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Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation

21 January 2018

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Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development

21 January 2018

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A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

21 January 2018

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p53 in recombination and repair

21 January 2018

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HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300 and P/CAF-dependent p53 acetylation

21 January 2018

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p27(Kip1) is a microtubule-associated protein that promotes microtubule polymerization during neuron migration.

21 January 2018

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Epigenetic induction of the Ink4a/Arf locus prevents Schwann cell overproliferation during nerve regeneration and after tumorigenic challenge.

21 January 2018

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CREB is a novel nuclear target of PTEN phosphatase

21 January 2018

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Role of the integrin-linked kinase (ILK) in determining neuronal polarity

21 January 2018

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Growth and turning properties of adult glial cell-derived neurotrophic factor coreceptor α1 nonpeptidergic sensory neurons

21 January 2018

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PTEN, a widely known negative regulator of insulin/PI3K signaling, positively regulates neuronal insulin resistance

21 January 2018

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The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

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Noxa is a critical mediator of p53-dependent motor neuron death after nerve injury in adult mouse

21 January 2018

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Inhibition of cyclin-dependent kinase activity triggers neuronal differentiation of mouse neuroblastoma cells

21 January 2018

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Developmental expression of mouse Krüppel-like transcription factor KLF7 suggests a potential role in neurogenesis

21 January 2018

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Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system

21 January 2018

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Impaired axonal regeneration by isolectin B4-binding dorsal root ganglion neurons in vitro.

21 January 2018

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Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

21 January 2018

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Retracted: Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines

21 January 2018

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Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats

21 January 2018

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The growth factor SVH-1 regulates axon regeneration in C. elegans via the JNK MAPK cascade

21 January 2018

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Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction

21 January 2018

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PTEN deletion enhances the regenerative ability of adult corticospinal neurons

21 January 2018

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SCYL1BP1 modulates neurite outgrowth and regeneration by regulating the Mdm2/p53 pathway

21 January 2018

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Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation.

21 January 2018

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Neural plasticity after peripheral nerve injury and regeneration

21 January 2018

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p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex

21 January 2018

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Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway

21 January 2018

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Apoptosis in Schwann cell cultures is closely interrelated with the activity of the ubiquitin-proteasome proteolytic pathway

21 January 2018

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Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system

21 January 2018

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Jab1 regulates Schwann cell proliferation and axonal sorting through p27.

21 January 2018

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A novel function for p53: regulation of growth cone motility through interaction with Rho kinase

21 January 2018

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c-Jun N-terminal kinase 1 (JNK1) is required for coordination of netrin signaling in axon guidance

21 January 2018

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Synergistic regulation of Schwann cell proliferation by heregulin and forskolin

21 January 2018

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Plasticity of motor systems after incomplete spinal cord injury

21 January 2018

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(-)-Epigallocatechin-3-gallate (EGCG) attenuates peripheral nerve degeneration in rat sciatic nerve crush injury.

21 January 2018

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Dynamic changes of p27(kip1) and Skp2 expression in injured rat sciatic nerve.

21 January 2018

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CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

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Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity

21 January 2018

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Accelerated axon outgrowth, guidance, and target reinnervation across nerve transection gaps following a brief electrical stimulation paradigm.

21 January 2018

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Regeneration of diabetic axons is enhanced by selective knockdown of the PTEN gene

21 January 2018

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A role for the retinoblastoma protein as a regulator of mouse osteoblast cell adhesion: implications for osteogenesis and osteosarcoma formation

21 January 2018

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Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β

21 January 2018

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Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

21 January 2018

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Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity

21 January 2018

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Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats.

21 January 2018

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A p53-CBP/p300 transcription module is required for GAP-43 expression, axon outgrowth, and regeneration

21 January 2018

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The tumor suppressor p53 transcriptionally regulates cGKI expression during neuronal maturation and is required for cGMP-dependent growth cone collapse

21 January 2018

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p21Cip1/WAF1 regulates radial axon growth and enhances motor functional recovery in the injured peripheral nervous system

21 January 2018

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Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.

21 January 2018

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Blinded by the Light: The Growing Complexity of p53

21 January 2018

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Schwann cells direct peripheral nerve regeneration through the Netrin-1 receptors, DCC and Unc5H2.

21 January 2018

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The Sp1 family of transcription factors is involved in p27(Kip1)-mediated activation of myelin basic protein gene expression

21 January 2018

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Satellite cell proliferation in the adult rat trigeminal ganglion results from the release of a mitogenic protein from explanted sensory neurons

21 January 2018

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Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism

21 January 2018

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microRNA-222 targeting PTEN promotes neurite outgrowth from adult dorsal root ganglion neurons following sciatic nerve transection

21 January 2018

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The challenges and beauty of peripheral nerve regrowth

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/EJN.13018

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4 September 2017

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