(Q38568978)

English

Adenosine 3',5'-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors

scientific article published on 25 August 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Adenosine 3',5'-cyclic monophosphate (cAMP)-dependent phosphoregulation of mitochondrial complex I is inhibited by nucleoside reverse transcriptase inhibitors (English)

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

author name string

Kaleb C Lund

1

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Kendall B Wallace

2

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

publication date

25 August 2007

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Toxicology and Applied Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

226

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

1

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

94-106

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2390784

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Selective fluorescent imaging of superoxide in vivo using ethidium-based probes

1 reference

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6 September 2017

Energy converting NADH:quinone oxidoreductase (complex I).

1 reference

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6 September 2017

Cell culture models for the investigation of NRTI-induced mitochondrial toxicity. Relevance for the prediction of clinical toxicity

1 reference

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Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism

1 reference

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Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence

1 reference

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6 September 2017

Activity profiles of deoxynucleoside kinases and 5'-nucleotidases in cultured adipocytes and myoblastic cells: insights into mitochondrial toxicity of nucleoside analogs

1 reference

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Kinase signaling cascades in the mitochondrion: a matter of life or death.

1 reference

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Molecular genetics of complex I-deficient Chinese hamster cell lines

1 reference

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6 September 2017

Direct, DNA pol-gamma-independent effects of nucleoside reverse transcriptase inhibitors on mitochondrial bioenergetics

1 reference

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6 September 2017

Phosphorylation of thymidine and AZT in heart mitochondria: elucidation of a novel mechanism of AZT cardiotoxicity

1 reference

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6 September 2017

Characterization of dynamic and steady-state protein phosphorylation using a fluorescent phosphoprotein gel stain and mass spectrometry

1 reference

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6 September 2017

Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I).

1 reference

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6 September 2017

The phosphorylation of subunits of complex I from bovine heart mitochondria.

1 reference

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6 September 2017

Hepatoma HepG2 cells as a model for in vitro studies on mitochondrial toxicity of antiviral drugs: which correlation with the patient?

1 reference

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6 September 2017

Proton pumping by NADH:ubiquinone oxidoreductase. A redox driven conformational change mechanism?

1 reference

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6 September 2017

The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification

1 reference

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6 September 2017

Topology of superoxide production from different sites in the mitochondrial electron transport chain

1 reference

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6 September 2017

Evidence of undiscovered cell regulatory mechanisms: phosphoproteins and protein kinases in mitochondria.

1 reference

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6 September 2017

Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase

1 reference

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6 September 2017

Mitochondrial toxicity and HIV therapy

1 reference

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6 September 2017

Mutation in the NDUFS4 gene of complex I abolishes cAMP-dependent activation of the complex in a child with fatal neurological syndrome

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6 September 2017

Pronucleotides: toward the in vivo delivery of antiviral and anticancer nucleotides

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6 September 2017

Clinical manifestations and management of antiretroviral nucleoside analog-related mitochondrial toxicity

1 reference

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6 September 2017

Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity.

1 reference

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6 September 2017

cAMP-dependent phosphorylation of the nuclear encoded 18-kDa (IP) subunit of respiratory complex I and activation of the complex in serum-starved mouse fibroblast cultures

1 reference

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6 September 2017

Differential effects of antiretroviral nucleoside analogs on mitochondrial function in HepG2 cells

1 reference

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6 September 2017

Molecular mechanism of the short-term cardiotoxicity caused by 2',3'-dideoxycytidine (ddC): modulation of reactive oxygen species levels and ADP-ribosylation reactions

1 reference

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6 September 2017

Role of reactive oxygen species and poly-ADP-ribose polymerase in the development of AZT-induced cardiomyopathy in rat.

1 reference

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6 September 2017

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

1 reference

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6 September 2017

Diverging substrate specificity of pure human thymidine kinases 1 and 2 against antiviral dideoxynucleosides

1 reference

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6 September 2017

DNA Polymerases versus HIV Reverse Transcriptase in AIDS Therapy

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6 September 2017

Intracellular zidovudine (ZDV) and ZDV phosphates as measured by a validated combined high-pressure liquid chromatography-radioimmunoassay procedure

1 reference

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6 September 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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6 September 2017

Zidovudine inhibits protein kinase C activity in human chronic myeloid (K562) cells.

1 reference

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14 September 2017

Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2390784

14 September 2017

Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis

1 reference

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14 September 2017

Cyclic adenosine monophosphate-dependent phosphorylation of mammalian mitochondrial proteins: enzyme and substrate characterization and functional role.

1 reference

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27 September 2017

A rapid and sensitive method for simultaneous determination of lamivudine and zidovudine in human serum by on-line solid-phase extraction coupled to liquid chromatography/tandem mass spectrometry detection

1 reference

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The transition between active and de-activated forms of NADH:ubiquinone oxidoreductase (Complex I) in the mitochondrial membrane of Neurospora crassa

1 reference

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23 June 2018

Mitochondrial sensitivity to AZT.

1 reference

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23 June 2018

Evidence for rapid consumption of millimolar concentrations of cytoplasmic ATP during rigor-contracture of metabolically compromised single cardiomyocytes

1 reference

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23 June 2018

Direct effects of nucleoside reverse transcriptase inhibitors on rat cardiac mitochondrial bioenergetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2390784

31 August 2018

AZT induces oxidative damage to cardiac mitochondria: protective effect of vitamins C and E.

1 reference

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31 August 2018

Regulation of NADH/CoQ oxidoreductase: do phosphorylation events affect activity?

1 reference

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31 August 2018

Contribution of the phosphorylable complex I in the growth phase-dependent respiration of C6 glioma cells in vitro

1 reference

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31 August 2018

Analysis of the subunit composition of complex I from bovine heart mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2390784

31 August 2018

Inhibition of phosphate transport in rat heart mitochondria by 3'-azido-3'-deoxythymidine due to stimulation of superoxide anion mitochondrial production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2390784

31 August 2018

Azidothymidine causes functional and structural destruction of mitochondria, glutathione deficiency and HIV-1 promoter sensitization

1 reference

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31 August 2018

Generation of reactive oxygen species by the mitochondrial electron transport chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2390784

31 August 2018

Serine (threonine) phosphatase(s) acting on cAMP-dependent phosphoproteins in mammalian mitochondria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2390784

31 August 2018

Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2390784

31 August 2018

Catalytic activity of NADH-ubiquinone oxidoreductase (complex I) in intact mitochondria. evidence for the slow active/inactive transition.

1 reference

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31 August 2018

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1 reference

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31 August 2018

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1 reference

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31 August 2018

AZT causes tissue-specific inhibition of mitochondrial bioenergetic function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2390784

31 August 2018

Mechanisms of toxicity of 3'-azido-3'-deoxythymidine. Its interaction with adenylate kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2390784

31 August 2018

Inhibition of nucleoside diphosphate kinase in rat liver mitochondria by added 3′-azido-3′-deoxythymidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal skeletal and cardiac muscle mitochondria induced by zidovudine (AZT) in human muscle in vitro and in an animal model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and bioavailability of zidovudine in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug monitoring of antiretroviral therapy for HIV-1 infection: method validation and results of a pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear-encoded 18 kDa (IP) AQDQ subunit of bovine heart complex I is phosphorylated by the mitochondrial cAMP-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Ca2+ ions on the slow active/inactive transition of the mitochondrial NADH-ubiquinone reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of proteins phosphorylated by the cAMP-dependent protein kinase of bovine heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP-dependent protein kinase and phosphoproteins in mammalian mitochondria. An extension of the cAMP-mediated intracellular signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mass spectrometric identification of a novel phosphorylation site in subunit NDUFA10 of bovine mitochondrial complex I

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Editorial response: hyperlactatemia and hepatic steatosis as features of mitochondrial toxicity of nucleoside analogue reverse transcriptase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 24-kDa subunit of the bovine mitochondrial NADH:ubiquinone oxidoreductase is a G protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of acidosis and ATP depletion on cardiac muscle electron transfer complex I

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of transhydrogenase reaction catalyzed by the mitochondrial NADH-ubiquinone oxidoreductase (Complex I) imply more than one catalytic nucleotide-binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/17904600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.TAAP.2007.08.015

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

4 September 2017

ResearchGate publication ID

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