(Q38569499)

4 September 2017

title

Age-related changes in natural killer cell repertoires: impact on NK cell function and immune surveillance (English)

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4 September 2017

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2

Markus Uhrberg

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4 September 2017

Angela R Manser

1

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4 September 2017

publication date

19 August 2015

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Cancer Immunology, Immunotherapy

4 September 2017

published in

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4 September 2017

volume

65

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4 September 2017

issue

4

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4 September 2017

page(s)

417-426

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https://scigraph.springernature.com/pub.10.1007/s00262-015-1750-0

4 September 2017

exact match

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cites work

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Reduced release and binding of perforin at the immunological synapse underlies the age-related decline in natural killer cell cytotoxicity.

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Human NK cells proliferate and die in vivo more rapidly than T cells in healthy young and elderly adults

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Reciprocal age related change in natural killer cell receptors for MHC class I.

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Effect of age and CMV on NK cell subpopulations

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Ageing is associated with a decline in peripheral blood CD56bright NK cells

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Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education

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NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs

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CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset.

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Education of hyporesponsive NK cells by cytokines

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The abundant NK cells in human secondary lymphoid tissues require activation to express killer cell Ig-like receptors and become cytolytic

21 January 2018

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Impaired cytotoxicity associated with defective natural killer cell differentiation in myelodysplastic syndromes

21 January 2018

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Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset

21 January 2018

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CD56brightCD16- killer Ig-like receptor- NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation.

21 January 2018

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Different rates of telomere shortening and telomerase activity reduction in CD8 T and CD16 NK lymphocytes with ageing.

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Natural killer cell development and maturation in aged mice.

21 January 2018

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The aged nonhematopoietic environment impairs natural killer cell maturation and function

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Human-specific evolution of killer cell immunoglobulin-like receptor recognition of major histocompatibility complex class I molecules

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Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis

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HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

21 January 2018

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Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

21 January 2018

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ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor

21 January 2018

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Licensing of natural killer cells by host major histocompatibility complex class I molecules

21 January 2018

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A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules

21 January 2018

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Human NK cell education by inhibitory receptors for MHC class I.

21 January 2018

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Neonatal NK-cell repertoires are functionally, but not structurally, biased toward recognition of self HLA class I.

21 January 2018

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A model for the differentiation of human natural killer cells. Studies on the in vitro activation of Leu-11+ granular lymphocytes with a natural killer-sensitive tumor cell, K562

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21 January 2018

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The impact of CMV infection on survival in older humans

21 January 2018

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Imprint of human cytomegalovirus infection on the NK cell receptor repertoire

21 January 2018

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Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors

21 January 2018

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NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs

21 January 2018

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Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus.

21 January 2018

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CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients.

21 January 2018

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Human cytomegalovirus infection is associated with increased proportions of NK cells that express the CD94/NKG2C receptor in aviremic HIV-1-positive patients.

21 January 2018

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Early human cytomegalovirus replication after transplantation is associated with a decreased relapse risk: evidence for a putative virus-versus-leukemia effect in acute myeloid leukemia patients

21 January 2018

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Epidemiology, classification and prognosis of adults and children with myelodysplastic syndromes.

21 January 2018

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Insufficient stromal support in MDS results from molecular and functional deficits of mesenchymal stromal cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00262-015-1750-0

The host environment is responsible for aging-related functional NK cell deficiency

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00262-015-1750-0

Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00262-015-1750-0

In vivo kinetics of human natural killer cells: the effects of ageing and acute and chronic viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-015-1750-0

Human NK cells display major phenotypic and functional changes over the life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-015-1750-0

10.1007/S00262-015-1750-0

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

4 September 2017

1051704048

0 references

1 reference