(Q38581733)

4 September 2017

Recent trends in preclinical drug-drug interaction studies of flavonoids--Review of case studies, issues and perspectives (English)

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4 September 2017

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Nuggehally R Srinivas

series ordinal

1

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4 September 2017

6 September 2015

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4 September 2017

Phytotherapy Research

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4 September 2017

29

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4 September 2017

11

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4 September 2017

1679-1691

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Intestinal absorption, metabolism, and excretion of (-)-epicatechin in healthy humans assessed by using an intestinal perfusion technique

4 September 2017

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Anti-cancer efficacy of silybin derivatives -- a structure-activity relationship

21 January 2018

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Herb-drug interactions: challenges and opportunities for improved predictions.

21 January 2018

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A phase II study of flavopiridol (Alvocidib) in combination with docetaxel in refractory, metastatic pancreatic cancer

21 January 2018

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Marked decrease of cyclosporin absorption caused by phellamurin in rats

21 January 2018

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Metabolism of flavonoids via enteric recycling: role of intestinal disposition

21 January 2018

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Pharmacokinetics and modeling of quercetin and metabolites

21 January 2018

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Dietary assumption of plant polyphenols and prevention of allergy

21 January 2018

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Effects of the antioxidant baicalein on the pharmacokinetics of nimodipine in rats: a possible role of P-glycoprotein and CYP3A4 inhibition by baicalein

21 January 2018

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Effects of myricetin, an antioxidant, on the pharmacokinetics of losartan and its active metabolite, EXP-3174, in rats: possible role of cytochrome P450 3A4, cytochrome P450 2C9 and P-glycoprotein inhibition by myricetin

21 January 2018

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Effects of quercetin on the bioavailability of doxorubicin in rats: role of CYP3A4 and P-gp inhibition by quercetin

21 January 2018

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Effects of oral epigallocatechin gallate on the oral pharmacokinetics of verapamil in rats

21 January 2018

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Flavonoids and isoflavonoids - a gold mine for metabolic engineering.

21 January 2018

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Baicalin suppresses lung carcinoma and lung metastasis by SOD mimic and HIF-1alpha inhibition

21 January 2018

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Effect of quercetin on CYP3A activity in Chinese healthy participants

21 January 2018

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Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock.

21 January 2018

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Flavonoids and polymer derivatives as CYP3A4 inhibitors for improved oral drug bioavailability

21 January 2018

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Phase I study of flavopiridol in combination with Paclitaxel and Carboplatin in patients with non-small-cell lung cancer

21 January 2018

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Disposition and metabolism of [2-14C]quercetin-4'-glucoside in rats

21 January 2018

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Phytonutrients as therapeutic agents

21 January 2018

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Phase I trial of bortezomib (PS-341; NSC 681239) and "nonhybrid" (bolus) infusion schedule of alvocidib (flavopiridol; NSC 649890) in patients with recurrent or refractory indolent B-cell neoplasms

21 January 2018

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Quercetin significantly decreased cyclosporin oral bioavailability in pigs and rats

21 January 2018

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Potential risk of mulberry-drug interaction: modulation on P-glycoprotein and cytochrome P450 3A.

21 January 2018

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The challenge of developing green tea polyphenols as therapeutic agents

21 January 2018

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Biochanin A inhibits endothelial cell functions and proangiogenic pathways: implications in glioma therapy

21 January 2018

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Disposition of flavonoids via enteric recycling: enzyme-transporter coupling affects metabolism of biochanin A and formononetin and excretion of their phase II conjugates

21 January 2018

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Significant decrease of cyclosporine bioavailability in rats caused by a decoction of the roots of Scutellaria baicalensis

21 January 2018

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Effects of silibinin, inhibitor of CYP3A4 and P-glycoprotein in vitro, on the pharmacokinetics of paclitaxel after oral and intravenous administration in rats

21 January 2018

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Enhanced bioavailability of etoposide after oral or intravenous administration of etoposide with kaempferol in rats

21 January 2018

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Effects of baicalein on the pharmacokinetics of tamoxifen and its main metabolite, 4-hydroxytamoxifen, in rats: possible role of cytochrome P450 3A4 and P-glycoprotein inhibition by baicalein

21 January 2018

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Enteric disposition and recycling of flavonoids and ginkgo flavonoids

21 January 2018

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The cyclin-dependent kinase inhibitor flavopiridol potentiates doxorubicin efficacy in advanced sarcomas: preclinical investigations and results of a phase I dose-escalation clinical trial

21 January 2018

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Disposition of flavonoids impacts their efficacy and safety

21 January 2018

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Epigallocatechin-3-gallate (EGCG) for clinical trials: more pitfalls than promises?

21 January 2018

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The Influence of Single-Dose and Short-Term Administration of Quercetin on the Pharmacokinetics of Midazolam in Humans

21 January 2018

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Antioxidant and anti-inflammatory properties of the citrus flavonoids hesperidin and hesperetin: an updated review of their molecular mechanisms and experimental models.

21 January 2018

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Flavonoids at the pharma-nutrition interface: Is a therapeutic index in demand?

21 January 2018

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Novel insights into the pharmacology of flavonoids

21 January 2018

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Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin--a mini-review

21 January 2018

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Effect of morin on pharmacokinetics of piracetam in rats, in vitro enzyme kinetics and metabolic stability assay using rapid UPLC method

21 January 2018

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Investigation of CYP3A4 and CYP2D6 Interactions of Withania somnifera and Centella asiatica in Human Liver Microsomes

21 January 2018

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Phase I study of the cyclin-dependent kinase inhibitor flavopiridol in combination with paclitaxel in patients with advanced solid tumors.

21 January 2018

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Reduced bioavailability of tamoxifen and its metabolite 4-hydroxytamoxifen after oral administration with biochanin A (an isoflavone) in rats.

21 January 2018

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Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells

21 January 2018

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Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using felodipine and hesperetin in combination in Wistar rats and everted rat gut sacs in vitro

21 January 2018

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Tigecycline and cyclosporine interaction-an interesting case of biliary-excreted drug enhancing the oral bioavailability of cyclosporine

21 January 2018

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Baicalin, an emerging multi-therapeutic agent: pharmacodynamics, pharmacokinetics, and considerations from drug development perspectives

21 January 2018

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Biochanin a: understanding the complexities in the paradoxical drug-drug interaction potential

21 January 2018

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High serum concentrations of cyclosporin related to administration of tigecycline

21 January 2018

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Phase I clinical and pharmacokinetic study of flavopiridol administered as a daily 1-hour infusion in patients with advanced neoplasms

21 January 2018

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Glucuronidation and subsequent biliary excretion of mycophenolic acid in rat sandwich-cultured hepatocytes

21 January 2018

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Phase I clinical and pharmacokinetic trial of the cyclin-dependent kinase inhibitor flavopiridol

21 January 2018

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Flavonoids from fruit and vegetables: a focus on cardiovascular risk factors

21 January 2018

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Quercetin pretreatment increases the bioavailability of pioglitazone in rats: involvement of CYP3A inhibition

21 January 2018

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Isoflavones: estrogenic activity, biological effect and bioavailability

21 January 2018

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Modulatory effects of quercetin and rutin on the activity, expression and inducibility of CYP1A1 in intestinal HCT-8 cells.

21 January 2018

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Effect of silibinin on the pharmacokinetics of nitrendipine in rabbits

21 January 2018

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Inhibitory effect of silybin on pharmacokinetics of imatinib in vivo and in vitro.

21 January 2018

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Bioavailability and pharmacokinetics of genistein: mechanistic studies on its ADME.

21 January 2018

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Quercetin and rutin reduced the bioavailability of cyclosporine from Neoral, an immunosuppressant, through activating P-glycoprotein and CYP 3A4.

21 January 2018

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Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport

21 January 2018

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Interactions between the flavonoid biochanin A and P-glycoprotein substrates in rats: in vitro and in vivo

21 January 2018

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Icariin: does it have an osteoinductive potential for bone tissue engineering?

21 January 2018

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Puerarin: a review of pharmacological effects

21 January 2018

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An in vitro method to simulate phenolic compound release from the food matrix in the gastrointestinal tract

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PTR.5447

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4 September 2017

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PubMed ID

26343418