(Q38600541)

4 September 2017

PIKfyve activity regulates reformation of terminal storage lysosomes from endolysosomes (English)

1 reference

4 September 2017

4

Guillaume van Niel

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Graça Raposo

series ordinal

3

object named as

Graça Raposo

1 reference

4 September 2017

Christin Bissig

1

1 reference

PubMed ID

28857423

4 September 2017

Ilse Hurbain

series ordinal

2

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4 September 2017

31 August 2017

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4 September 2017

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Phosphatidylinositol 3,5-bisphosphate: low abundance, high significance

4 September 2017

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In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.

21 January 2018

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Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J

21 January 2018

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Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve

21 January 2018

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A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding

21 January 2018

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Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice.

21 January 2018

1 reference

Lysosomes: fusion and function

21 January 2018

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Endolysosomes Are the Principal Intracellular Sites of Acid Hydrolase Activity

21 January 2018

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Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes

21 January 2018

1 reference

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse

21 January 2018

1 reference

FIG4 regulates lysosome membrane homeostasis independent of phosphatase function

21 January 2018

1 reference

Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J

21 January 2018

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A lipid associated with the antiphospholipid syndrome regulates endosome structure and function

21 January 2018

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Recycling Compartments and the Internal Vesicles of Multivesicular Bodies Harbor Most of the Cholesterol Found in the Endocytic Pathway

21 January 2018

1 reference

PIKfyve regulation of endosome-linked pathways

21 January 2018

1 reference

Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death

21 January 2018

1 reference

ESCRTs and Fab1 regulate distinct steps of autophagy

21 January 2018

1 reference

The Fab1/PIKfyve phosphoinositide phosphate kinase is not necessary to maintain the pH of lysosomes and of the yeast vacuole.

21 January 2018

1 reference

AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve

21 January 2018

1 reference

Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors

21 January 2018

1 reference

Electron tomography of early melanosomes: implications for melanogenesis and the generation of fibrillar amyloid sheets

21 January 2018

1 reference

Mucolipidosis type IV protein TRPML1-dependent lysosome formation

21 January 2018

1 reference

Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes

21 January 2018

1 reference

The role of intraorganellar Ca(2+) in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organelles

21 January 2018

1 reference

PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

21 January 2018

1 reference

Reactivation of Lysosomal Ca2+ Efflux Rescues Abnormal Lysosomal Storage in FIG4-Deficient Cells

21 January 2018

1 reference

PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment.

21 January 2018

1 reference

Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis

21 January 2018

1 reference

Neurologic, gastric, and opthalmologic pathologies in a murine model of mucolipidosis type IV

21 January 2018

1 reference

Endo-lysosomal TRP mucolipin-1 channels trigger global ER Ca2+ release and Ca2+ influx

21 January 2018

1 reference

Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1

21 January 2018

1 reference

The signaling lipid PI(3,5)P₂ stabilizes V₁-V(o) sector interactions and activates the V-ATPase

21 January 2018

1 reference

Endocytic delivery to lysosomes mediated by concurrent fusion and kissing events in living cells.

21 January 2018

1 reference

Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cells

21 January 2018

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Pmel17 initiates premelanosome morphogenesis within multivesicular bodies

21 January 2018

1 reference

Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3.

21 January 2018

1 reference

Improving FRET dynamic range with bright green and red fluorescent proteins

21 January 2018

1 reference

The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/TRA.12525

1 reference

4 September 2017

1 reference

PubMed ID

28857423