(Q38646923)

5 September 2017

New insights into the immunopathology and control of dengue virus infection (English)

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5 September 2017

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Juthathip Mongkolsapaya

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2

object named as

Juthathip Mongkolsapaya

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5 September 2017

1

Gavin Screaton

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5 September 2017

Sophie Yacoub

3

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5 September 2017

Catherine Roberts

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4

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5 September 2017

language of work or name

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1 November 2015

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Nature Reviews Immunology

5 September 2017

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5 September 2017

15

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5 September 2017

745-759

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5 September 2017

12

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https://scigraph.springernature.com/pub.10.1038/nri3916

5 September 2017

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A ligand-binding pocket in the dengue virus envelope glycoprotein

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Structure of the immature dengue virus at low pH primes proteolytic maturation

31 March 2020

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A structural perspective of the flavivirus life cycle

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31 March 2020

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31 March 2020

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Cross-reacting antibodies enhance dengue virus infection in humans

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A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

31 March 2020

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Structural changes and functional control of the tick-borne encephalitis virus glycoprotein E by the heterodimeric association with protein prM

31 March 2020

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Immature Dengue Virus: A Veiled Pathogen?

31 March 2020

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Maturation of flaviviruses starts from one or more icosahedrally independent nucleation centres

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Receptors and routes of dengue virus entry into the host cells

31 March 2020

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Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement

31 March 2020

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Differing influences of virus burden and immune activation on disease severity in secondary dengue-3 virus infections

31 March 2020

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High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever

31 March 2020

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Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms

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A complex interplay among virus, dendritic cells, T cells, and cytokines in dengue virus infections

31 March 2020

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Early Immune Activation in Acute Dengue Illness Is Related to Development of Plasma Leakage and Disease Severity

31 March 2020

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Pathophysiologic and prognostic role of cytokines in dengue hemorrhagic fever

31 March 2020

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Gram-positive and gram-negative bacterial toxins in sepsis: a brief review

31 March 2020

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Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

31 March 2020

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Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate

31 March 2020

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Secreted NS1 of Dengue Virus Attaches to the Surface of Cells via Interactions with Heparan Sulfate and Chondroitin Sulfate E

31 March 2020

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Antagonism of the complement component C4 by flavivirus nonstructural protein NS1.

31 March 2020

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Influence of mast cells on dengue protective immunity and immune pathology

31 March 2020

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Dengue: defining protective versus pathologic immunity

31 March 2020

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Immunodominant T-cell responses to dengue virus NS3 are associated with DHF.

31 March 2020

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Definition of an epitope on NS3 recognized by human CD4+ cytotoxic T lymphocyte clones cross-reactive for dengue virus types 2, 3, and 4.

31 March 2020

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Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever

31 March 2020

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T cell responses in dengue hemorrhagic fever: are cross-reactive T cells suboptimal?

31 March 2020

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Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells

31 March 2020

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A Protective Role for Dengue Virus-Specific CD8+ T Cells

31 March 2020

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Elucidating the role of T cells in protection against and pathogenesis of dengue virus infections

31 March 2020

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Differential targeting of viral components by CD4+ versus CD8+ T lymphocytes in dengue virus infection.

31 March 2020

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Protection from secondary dengue virus infection in a mouse model reveals the role of serotype cross-reactive B and T cells

31 March 2020

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Dominant recognition by human CD8+ cytotoxic T lymphocytes of dengue virus nonstructural proteins NS3 and NS1.2a

31 March 2020

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Early CD69 expression on peripheral blood lymphocytes from children with dengue hemorrhagic fever

31 March 2020

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T cell responses to an HLA-B*07-restricted epitope on the dengue NS3 protein correlate with disease severity

31 March 2020

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Timing of CD8+ T cell responses in relation to commencement of capillary leakage in children with dengue

31 March 2020

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Cross-reactivity and expansion of dengue-specific T cells during acute primary and secondary infections in humans

31 March 2020

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Virus-specific T lymphocytes home to the skin during natural dengue infection

31 March 2020

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Dengue virus-specific human T cell clones. Serotype crossreactive proliferation, interferon gamma production, and cytotoxic activity

31 March 2020

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Disquisitions of Original Antigenic Sin. I. Evidence in man

31 March 2020

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The role of T cell antagonism and original antigenic sin in genetic immunization

31 March 2020

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Dengue virus infection elicits highly polarized CX3CR1+ cytotoxic CD4+ T cells associated with protective immunity

31 March 2020

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Human genetic determinants of dengue virus susceptibility

31 March 2020

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CD4+ T cells are not required for the induction of dengue virus-specific CD8+ T cell or antibody responses but contribute to protection after vaccination

31 March 2020

1 reference

CD8+ T Cells Can Mediate Short-Term Protection against Heterotypic Dengue Virus Reinfection in Mice

31 March 2020

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Controversies in dengue pathogenesis

31 March 2020

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Secondary infection as a risk factor for dengue hemorrhagic fever/dengue shock syndrome: an historical perspective and role of antibody-dependent enhancement of infection

31 March 2020

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Leukocyte immunoglobulin-like receptor B1 is critical for antibody-dependent dengue

31 March 2020

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Animal models of dengue virus infection

31 March 2020

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Maternal antibody and viral factors in the pathogenesis of dengue virus in infants

31 March 2020

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Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored

31 March 2020

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Modeling antibody-enhanced dengue virus infection and disease in mice: protection or pathogenesis?

31 March 2020

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Association of FcγRIIa Polymorphism with Clinical Outcome of Dengue Infection: First Insight from Pakistan

31 March 2020

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Asymptomatic dengue infection in a Cuban population confirms the protective role of the RR variant of the FcgammaRIIa polymorphism

31 March 2020

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Susceptibility to dengue hemorrhagic fever in vietnam: evidence of an association with variation in the vitamin d receptor and Fc gamma receptor IIa genes.

31 March 2020

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Antibodies against the envelope glycoprotein promote infectivity of immature dengue virus serotype 2

31 March 2020

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A fusion-loop antibody enhances the infectious properties of immature flavivirus particles

31 March 2020

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An in-depth analysis of original antigenic sin in dengue virus infection

31 March 2020

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The Stoichiometry of Antibody-Mediated Neutralization and Enhancement of West Nile Virus Infection

31 March 2020

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Neutralizing antibodies after infection with dengue 1 virus

31 March 2020

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Research on dengue during World War II

31 March 2020

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Live attenuated tetravalent dengue vaccine

31 March 2020

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Phase 2 clinical trial of three formulations of tetravalent live-attenuated dengue vaccine in flavivirus-naïve adults

31 March 2020

1 reference

Safety and immunogenicity of attenuated dengue virus vaccines (Aventis Pasteur) in human volunteers

31 March 2020

1 reference

From research to phase III: preclinical, industrial and clinical development of the Sanofi Pasteur tetravalent dengue vaccine

31 March 2020

1 reference

Robust and Balanced Immune Responses to All 4 Dengue Virus Serotypes Following Administration of a Single Dose of a Live Attenuated Tetravalent Dengue Vaccine to Healthy, Flavivirus-Naive Adults

31 March 2020

1 reference

Safety and immunogenicity of a recombinant live attenuated tetravalent dengue vaccine (DENVax) in flavivirus-naive healthy adults in Colombia: a randomised, placebo-controlled, phase 1 study

31 March 2020

1 reference

Safety and immunogenicity of a rederived, live-attenuated dengue virus vaccine in healthy adults living in Thailand: a randomized trial

31 March 2020

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Safety and immunogenicity of a recombinant tetravalent dengue vaccine in 9-16 year olds: a randomized, controlled, phase II trial in Latin America.

31 March 2020

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Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial

31 March 2020

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Immunogenicity and safety of tetravalent dengue vaccine in 2-11 year-olds previously vaccinated against yellow fever: randomized, controlled, phase II study in Piura, Peru

31 March 2020

1 reference

Immunogenicity and safety of recombinant tetravalent dengue vaccine (CYD-TDV) in individuals aged 2-45 y: Phase II randomized controlled trial in Singapore

31 March 2020

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Live-attenuated, tetravalent dengue vaccine in children, adolescents and adults in a dengue endemic country: randomized controlled phase I trial in the Philippines

31 March 2020

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Efficacy of a tetravalent dengue vaccine in children in Latin America.

31 March 2020

1 reference

Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial

31 March 2020

1 reference

Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease

31 March 2020

1 reference

Evaluation of protective efficacy and immune mechanisms of using a non-structural protein NS1 in DNA vaccine against dengue 2 virus in mice

31 March 2020

1 reference

Protective immunity to DENV2 after immunization with a recombinant NS1 protein using a genetically detoxified heat-labile toxin as an adjuvant.

31 March 2020

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Sequential dengue virus infections detected in active and passive surveillance programs in Thailand, 1994-2010.

31 March 2020

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Reduced risk of disease during postsecondary dengue virus infections

31 March 2020

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Analysis of repeat hospital admissions for dengue to estimate the frequency of third or fourth dengue infections resulting in admissions and dengue hemorrhagic fever, and serotype sequences.

31 March 2020

1 reference

Evaluation of interferences between dengue vaccine serotypes in a monkey model.

31 March 2020

1 reference

Assessment of bivalent and tetravalent dengue vaccine formulations in flavivirus-naïve adults in Mexico

31 March 2020

1 reference

A single dose of any of four different live attenuated tetravalent dengue vaccines is safe and immunogenic in flavivirus-naive adults: a randomized, double-blind clinical trial

31 March 2020

1 reference

Safety and Immunogenicity of a Live Attenuated Tetravalent Dengue Vaccine Candidate in Flavivirus-Naive Adults: A Randomized, Double-Blinded Phase 1 Clinical Trial

31 March 2020

1 reference

Trials and tribulations on the path to developing a dengue vaccine

31 March 2020

1 reference

Genotype-specific neutralization and protection by antibodies against dengue virus type 3.

31 March 2020

1 reference

Monoclonal Antibodies That Bind to Domain III of Dengue Virus E Glycoprotein Are the Most Efficient Blockers of Virus Adsorption to Vero Cells

31 March 2020

1 reference

Characterization of an antigenic site that contains a dominant, type-specific neutralization determinant on the envelope protein domain III (ED3) of dengue 2 virus

31 March 2020

1 reference

Characterization of Dengue Virus Complex-Specific Neutralizing Epitopes on Envelope Protein Domain III of Dengue 2 Virus

31 March 2020

1 reference

Monoclonal antibody mapping of the envelope glycoprotein of the dengue 2 virus, Jamaica

31 March 2020

1 reference

The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1

31 March 2020

1 reference

Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2.

31 March 2020

1 reference

Type- and Subcomplex-Specific Neutralizing Antibodies against Domain III of Dengue Virus Type 2 Envelope Protein Recognize Adjacent Epitopes

31 March 2020

1 reference

Functional analysis of antibodies against dengue virus type 4 reveals strain-dependent epitope exposure that impacts neutralization and protection

31 March 2020

1 reference

Natural Strain Variation and Antibody Neutralization of Dengue Serotype 3 Viruses

31 March 2020

1 reference

Antibody Recognition and Neutralization Determinants on Domains I and II of West Nile Virus Envelope Protein

31 March 2020

1 reference

Antibodies to Envelope Glycoprotein of Dengue Virus during the Natural Course of Infection Are Predominantly Cross-Reactive and Recognize Epitopes Containing Highly Conserved Residues at the Fusion Loop of Domain II

31 March 2020

1 reference

Induction of Epitope-Specific Neutralizing Antibodies against West Nile Virus

31 March 2020

1 reference

Humoral Immune Responses of Dengue Fever Patients Using Epitope-Specific Serotype-2 Virus-Like Particle Antigens

31 March 2020

1 reference

Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope

31 March 2020

1 reference

Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus

31 March 2020

1 reference

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins

31 March 2020

1 reference

Antibodies targeting dengue virus envelope domain III are not required for serotype-specific protection or prevention of enhancement in vivo

31 March 2020

1 reference

Structural Analysis of a Dengue Cross-Reactive Antibody Complexed with Envelope Domain III Reveals the Molecular Basis of Cross-Reactivity

31 March 2020

1 reference

A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus

31 March 2020

1 reference

Structural Changes in Dengue Virus When Exposed to a Temperature of 37 C

31 March 2020

1 reference

Dengue structure differs at the temperatures of its human and mosquito hosts

31 March 2020

1 reference

DENGUE VIRUS. Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers

31 March 2020

1 reference

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus.

31 March 2020

1 reference

An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies

31 March 2020

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Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen

31 March 2020

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The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity

31 March 2020

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In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection

31 March 2020

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Persistence of circulating memory B cell clones with potential for dengue virus disease enhancement for decades following infection

31 March 2020

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Human monoclonal antibodies derived from memory B cells following live attenuated dengue virus vaccination or natural infection exhibit similar characteristics

31 March 2020

1 reference

The structural basis for serotype-specific neutralization of dengue virus by a human antibody

31 March 2020

1 reference

A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface

31 March 2020

1 reference

Recognition determinants of broadly neutralizing human antibodies against dengue viruses

31 March 2020

1 reference

Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354

31 March 2020

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A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins

31 March 2020

1 reference

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

31 March 2020

1 reference

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

31 March 2020

1 reference

Cardiovascular manifestations of the emerging dengue pandemic.

31 March 2020

1 reference

Clinical features of dengue in a large Vietnamese cohort: intrinsically lower platelet counts and greater risk for bleeding in adults than children

31 March 2020

1 reference

Dengue therapeutics, chemoprophylaxis, and allied tools: state of the art and future directions

31 March 2020

1 reference

Emerging flaviviruses: the spread and resurgence of Japanese encephalitis, West Nile and dengue viruses

31 March 2020

1 reference

Therapeutic efficacy of antibodies lacking Fcγ receptor binding against lethal dengue virus infection is due to neutralizing potency and blocking of enhancing antibodies [corrected].

31 March 2020

1 reference

Isolation of dengue virus-specific memory B cells with live virus antigen from human subjects following natural infection reveals the presence of diverse novel functional groups of antibody clones

31 March 2020

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Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions

31 March 2020

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31 March 2020

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12 December 2020

Dengue virus-specific, HLA-B35-restricted, human CD8+ cytotoxic T lymphocyte (CTL) clones. Recognition of NS3 amino acids 500 to 508 by CTL clones of two different serotype specificities.

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12 December 2020

Phase I trial of 16 formulations of a tetravalent live-attenuated dengue vaccine

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12 December 2020

Evidence That Maternal Dengue Antibodies Are Important in the Development of Dengue Hemorrhagic Fever in Infants

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12 December 2020

Predominance of HLA-restricted cytotoxic T-lymphocyte responses to serotype-cross-reactive epitopes on nonstructural proteins following natural secondary dengue virus infection

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12 December 2020

Cytokine storm of graft-versus-host disease: a critical effector role for interleukin-1.

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12 December 2020

The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein

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12 December 2020

Flavivirus serology by Western blot analysis

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12 December 2020

Risk factors in dengue shock syndrome: a prospective epidemiologic study in Rayong, Thailand. I. The 1980 outbreak

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12 December 2020

Dengue virus-specific, human CD4+ CD8- cytotoxic T-cell clones: multiple patterns of virus cross-reactivity recognized by NS3-specific T-cell clones

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12 December 2020

Identifiers

DOI

10.1038/NRI3916

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Dimensions Publication ID

5 September 2017

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