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Correlating conformational shift induction with altered inhibitor potency in a multidrug resistant HIV-1 protease variant.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
title
Correlating conformational shift induction with altered inhibitor potency in a multidrug resistant HIV-1 protease variant
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
main subject
multiple drug resistance
1 reference
based on heuristic
inferred from title
author
Ian Mitchelle S De Vera
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
author name string
Mandy E Blackburn
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Gail E Fanucci
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
language of work or name
English
0 references
publication date
28 September 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
number of pages
3
1 reference
based on heuristic
inferred from page(s)
published in
Biochemistry
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
volume
51
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
issue
40
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
page(s)
7813-7815
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
cites work
HIV-1 Protease: Structural Perspectives on Drug Resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
The higher barrier of darunavir and tipranavir resistance for HIV-1 protease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
Nine crystal structures determine the substrate envelope of the MDR HIV-1 protease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
Rotamer libraries of spin labelled cysteines for protein studies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
Solution structure of HIV-1 protease flaps probed by comparison of molecular dynamics simulation ensembles and EPR experiments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
Effect of the Active Site D25N Mutation on the Structure, Stability, and Ligand Binding of the Mature HIV-1 Protease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
HIV-1 protease: structure, dynamics, and inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
Recent advances and applications of site-directed spin labeling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
HIV-1 protease flaps spontaneously open and reclose in molecular dynamics simulations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
Crystal structures of a multidrug-resistant human immunodeficiency virus type 1 protease reveal an expanded active-site cavity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
Drug resistance in HIV-1 protease: Flexibility-assisted mechanism of compensatory mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
Curling of flap tips in HIV-1 protease as a mechanism for substrate entry and tolerance of drug resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
Sequence requirements of the HIV-1 protease flap region determined by saturation mutagenesis and kinetic analysis of flap mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
HIV protease: a novel chemotherapeutic target for AIDS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
The three-dimensional structure of the aspartyl protease from the HIV-1 isolate BRU
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
6 September 2017
HIV-1 protease mutations and protease inhibitor cross-resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
23 June 2018
Subtype polymorphisms among HIV-1 protease variants confer altered flap conformations and flexibility
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
23 June 2018
"Wide-open" 1.3 A structure of a multidrug-resistant HIV-1 protease as a drug target
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
23 June 2018
Highly drug-resistant HIV-1 clinical isolates are cross-resistant to many antiretroviral compounds in current clinical development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
23 June 2018
Reaction path and free energy calculations of the transition between alternate conformations of HIV-1 protease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
23 June 2018
Drug pressure selected mutations in HIV-1 protease alter flap conformations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
31 August 2018
Secondary mutations M36I and A71V in the human immunodeficiency virus type 1 protease can provide an advantage for the emergence of the primary mutation D30N.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4768727
retrieved
31 August 2018
Dynamics of "flap" structures in three HIV-1 protease/inhibitor complexes probed by total chemical synthesis and pulse-EPR spectroscopy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23009326
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Monitoring inhibitor-induced conformational population shifts in HIV-1 protease by pulsed EPR spectroscopy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23009326
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1021/BI301010Z
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
PMC publication ID
4768727
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
PubMed publication ID
23009326
1 reference
stated in
Europe PubMed Central
PMC publication ID
4768727
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23009326%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
ResearchGate publication ID
231177268
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